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Benefit of aspirin plus moderate-intensity oral anticoagulation compared with aspirin alone after acute coronary syndromesThe role of combination therapy with an oral anticoagulant and aspirin for patients recovering from an acute coronary syndrome is still being debated. The results of our meta-analysis showed that treatment with aspirin plus warfarin at international normalized ratio values between 2 and 3 significantly reduces the risk of major adverse events compared with aspirin alone but also increases the risk of major bleeding. For every 100 patients receiving combination therapy, approximately 3 major adverse events are prevented and 1 major hemorrhage occurs.
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FoundationOne CDx: A Broad Companion Diagnostic Test for Cancer TumorsVincent Miller, MD, chief medical officer of Foundation Medicine, discusses FoundationOne CDx, an FDA-approved diagnostic that is clinically validated for solid tumors.
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When to Perform Reconstructive Surgery in Children with Facial Birth DefectsBirth defects can set a family up for a lifetime of challenges, but thanks to some amazing advances in modern cosmetic surgery, there are options available to improve a child's quality of life.
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HIV/AIDS: Progress in TreatmentIn this podcast, Dr. Church reviews the developments of new treatments for HIV.
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Left ventricular apical ballooning syndrome: A case report of an unusual syndromeA 65-year-old woman with a history of anxiety disorder, dyslipidemia, and recently diagnosed celiac sprue was transferred to the heart center after presenting to a peripheral community hospital with marked fatigue, progressively worsening dyspnea on exertion, and bilateral lower extremity swelling with associated bilateral arm tingling.
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The Deceptive Income of PhysiciansPhysicians are among the most well-compensated professionals in the US, right? Well, it depends on how you look at it.
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Cell Phone-based Telemonitoring Helps Cancer: Patients Adhere to Treatment RegimensWireless technologies like cell phones and radio frequency identification can help improve treatment compliance and quality of life for cancer patients.
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Monitoring Hospital Care Through HCAHPSThe National Association for Healthcare Quality (NAHQ), the Agency for Healthcare Research and Quality (AHRQ), the Leapfrog Group, the Joint Commission, the Institute for Healthcare Improvement (IHI), and the Centers for Medicare and Medicaid Services (CMS) are just a few of the many national and local payers and regulatory agencies that have developed indicators to monitor quality of care.
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Can You Collect Disability Benefits For Burnout?Physician's applying for disability due to "burnout" need to be prepared to combat insurance companies seeking to trivialize and downplay the situation.
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Medication adherence and meaningful clinical markers in diabetes mellitusDiabetes mellitus is a chronic disease for which nonadherence to therapy is frequent.
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Impaired coronary blood flow reserve in prehypertension and functionDespite the fact that prehypertension has been shown to be associated with atherosclerosis and target-organ damage, no studies evaluating coronary flow reserve (CFR) among prehypertensive patients have been done. We assessed CFR in normotensive subjects, in subjects with prehypertension, and in newly diagnosed and never-treated subjects with established hypertension. We found that CFR was decreased in prehypertensive subjects, although not as significantly as in subjects with hypertension.
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Taxane-related Peripheral Neuropathy Associated with Better OutcomesFor patients with early breast cancer, peripheral neurotoxicity is an unfortunate side effect of treatment with taxanes, but there may be a silver lining.
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Novel Therapy First to Extend Survival in Advanced MelanomaThe results of a randomized phase III study showed that when ipilimumab (also known as MDX-010) was administered with or without the gp100 peptide vaccine, it extended survival by 34% compared with the gp100 peptide vaccine alone in patients with previously treated advanced melanoma.
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Dronedarone: Boon or bust?Atrial fibrillation affects over 2.2 million Americans and is estimated to affect up to 10 million by 2050.
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Proposed Physician Fee Schedule Update Implements Reform ProvisionsCMS published its annual regulatory update to the Medicare Physician Fee Schedule, including rules implementing key provisions of the Affordable Care Act.
