Addiction

The FDA has granted an orphan drug designation to Antidote Therapeutics, Inc.’s ATI-1013 for the treatment of Buerger’s disease.

The director of Pain Management and Palliative Care at the Englewood Hospital & Medical Center in Englewood, NJ, explains how analgesics may come to the forefront of pain management care.

How issues with pain in patients with Lyme disease or opioid-induced constipation can be managed in a timely, efficient manner.

New research finds patients hospitalized for alcohol dependence have lower rates of survival if they are also infected with hepatitis C.

The 30-person panel, including physicians and patients, recommended a median 12.5 tablets of 5mg opioid for 20 common procedures.

From 1999 to 2014, prevalence of opioid use disorder among women giving birth increased 333% nationally, according to a report from the Centers for Disease Control and Prevention.

The FDA accepted the NDA for NKTR-181, a drug with slowed entry into the brain that attenuates the dopamine release underlying euphoria.

Recent reports have suggested a higher-than-expected rate of problematic drinking among the elderly, prompting an examination of a number of factors that could be utilized as future predictors of alcohol-related outcomes.

New research finds patients with HIV and chronic pain are aware that opioids are addictive, yet most don’t receive common addiction-prevention monitoring.

Researchers identified 6 types of potentially inappropriate prescriptions, all of which were associated with higher hazards for all-cause mortality, 4 with non-fatal overdose, and 5 with fatal overdose.

The condition is characterized by a display of persistent or recurrent gaming behavior, online or offline, and can appear in continuous, episodic, and recurrent patterns.

The buprenorphine and naloxone sublingual film is approved for the treatment of opioid abuse disorder in combination with counseling and psychosocial support.

The guidelines included indications and contraindications, evidence supporting its use, and the use of nonparenteral forms of ketamine.

The NDA for the investigative long-acting subcutaneous buprenorphine injection was turned down in lieu of more data in January.

Physicians who received non-research opioid-related payments from the pharmaceutical industry in 2014 had 9.3% more opioid claims in 2015 than physicians who did not.

After 3 months, half of the patients reported no substance abuse, while the number of patients using drop to 2 (10%).

The therapy regimen is tolerable, safe, and effective for patients attempting to detoxify for an extended opioid agonist treatment.

Those who frequently use illicit drugs in public places were more likely to witness overdoses, and thus should be targeted for naloxone treatment training.

The Global Burden of Disease study found that US mortality has improved since 1990 — but has been caused by worse health measures.

The long-acting, single-dose nerve block can now be used for popularizing procedures such as total shoulder arthroplasty or rotator cuff repair.

Researchers observed that prescribing rates were cut by about 6% in at-risk populations from states with legalization laws in place.

A study has shown that those who underestimated their prescription rates decreased opioid prescriptions by 2.2 patients more over the next 12 months after being notified of their data.

A CDC analysis found that overall drug overdose death rates increased by 21.5%, but those involving synthetic opioids more than doubled.

A new study found that NAS rates have increased 433% from 2004 to 2014.

If approved, NTX-011 may help combat the nationwide opioid epidemic.

The president's remarks in New Hampshire Monday called for judicial action and a law enforcement-centric approach to the opioid epidemic.

Non-opioids fared better for patients with chronic back pain, or hip or knee osteoarthritic pain, in a 12-month study.

In addition to the outbreak, kratom is expected to have a similar risk of addiction, abuse and death as an opioid, the agency announced earlier this month.

Rare Disease Report sat down with acute intermittent porphyria patient Nichol Kirby who was diagnosed in 2015 and accused of being a drug seeker looking to feed an opioid addiction.

This would be the first and only non-opioid, non-addictive medication for management of opioid withdrawal.