Asthma

Trial results on novel multi-dose powder inhaler were revealed at AAAAI 2017.

Luz Fonacier, MD, Winthrop University Hospital, detailed the process of looking at eczema and contact dermatitis in an allergist's practice.

In an ideal world, interventions would have a pilot study before RCT.

Which recommendations decrease asthma morbidity in children with asthma?

Matthew Perzanowski, PhD, discusses allergic asthma environmental factors.

Relationship persists between dysfunctional breathing and poor asthma.

People who have trouble sleeping are likely to develop asthma.

Patients with severe allergic asthma should try omalizumab therapy.

Genetic biomarkers can be linked to severity and development of asthma.

Traffic-related air pollution could impact childhood asthma prevalence.

The expanded indication was granted under the FDA's priority review program.

Killing cockroaches from infested homes reduced asthma morbidity.

Surprising links exist between kids with asthma, parental influence, & anxiety.

Kids with asthma are four times more likely to have kidney stones.

An increase in asthma attacks in November could be linked to the weather.

The FDA approved two breath-activated inhalers to treat asthma.

FDA approved Symbicort for kids 6 to 12 years with uncontrolled asthma.

Previous studies have shown that “the gut microbiota differs in composition and diversity during the first months of life in children who later do or do not have allergic disease," but researchers who focused on immunoglobulin A prevalence made a different finding.

People most at risk of needing adrenaline auto-injectors tend not to know how to use them properly, studies have found. Physicians are blamed for the lapses.

The pros identified included the possibility of EMDs improving adherence, that the devices might help motivate patients through creating a sense of independence and accountability, and that the data generated could help in building a trusting relationship between clinician and patient.

Smoking teens, rogue genes, and mashed-up hookworms are among the many diverse, fascinating, and important asthma topics that came out of 2016.

Using data from the Inner-City Asthma Consortium, researchers were able to identify the factors that contribute to more than half the variance in asthma severity, including allergic sensitization and, significantly, environmental tobacco smoke.

Only 5-10% of asthma sufferers have "severe" asthma, but account for about 50% of the social cost of the disease. The current focus in research is on finding therapies to treat specific components of the inflammation.

A new article in the Journal of Allergy and Clinical Immunology argues that genetic studies of asthma, expected to be game-changers, have “delivered neither meaningful clinical diagnostic tools nor useful insights into disease pathogenesis.”

A study out of the University of Pittsburgh identifies significant comorbidity and negative outcomes in those with insomnia and asthma, and finds that even asthmatics who report no nighttime breathing disturbances still face a predisposition to sleeplessness.

Individuals with atopic asthma were recently found to have a distinctive bronchial bacterial microbiome that not only differs from those without asthma, but between asthmatics with phenotypes more responsive or resistant to inhaled corticosteroids.

An inhaled corticosteroid and long-acting beta2-agonist bronchodilator combination was found more beneficial for patients with Asthma-Chronic Obstructive Pulmonary Disease Overlap Syndrome (ACOS) than for those with COPD alone.

A recent survey of asthma treatment in intensive care units of children's hospitals in the US reveals wide variability between institutions in both medication and ventilation interventions.

Studies that found no connection are outliers, the authors of the new meta-analysis write. They believe the findings have been consistent enough to assert a certain link between pollution exposure and juvenile asthma, but they note that many important questions remain.

Severe asthma persists in nonsmoking and smoking patients on currently recommended therapy despite suppressed tissue inflammation within the proximal airway wall, according to a recent report.