Atherosclerotic Cardiovascular Disease

A systematic review and meta-analysis suggested the relative risk per Gy increased for all cardiovascular disease and for the four major subtypes of cardiovascular disease.

Data from the PROMISE II study detail the effects of transcatheter arterialization procedures with the LimFlow System for reducing the rate of amputation in people with chronic limb-threatening ischemia.

An analysis of more than 9000 adults aged 40 and older without known cardiovascular disease is shedding new light on the risk of myocardial infarction and mortality associated with subclinical coronary atherosclerosis.

High blood pressure and low fitness levels were each associated with an increased risk of CVD mortality independently of established and emerging risk factors in new findings.

An analysis of NHANES from 2013 - March 2020 suggest individuals with an indication for statin therapy for primary prevention based on 10-year risk saw low overall use across risk categories and race and ethnicity strata.

Erin Michos, MD, MHS, discusses her choices for top studies in lipidology from the American College of Cardiology 2023 Scientific Sessions.

A multinational study provides new insight into the impact of suboptimal sleep duration on risk of incident peripheral artery disease.

New research from Intermountain Healthcare presented at ACC 2023 examines the prognostic value of disproportionate CAC scores for 1 or more vessels relative to the value of total CAC score for predicting major adverse cardiovascular events.

With ACC 2023 in the rearview, the HCPLive editorial team compiled perspectives on the meeting’s top piece of news from half a dozen clinicians specializing in various subspecialties across the spectrum of cardiovascular care.

In a Q&A at ACC 2023, Drs. Alexandra Murphy and Birgit Vogel of Mount Sinai discuss sex-specific predictors of MACE and the need for individualization of care to achieve equity in cardiovascular health.

A genome-wide genetic association study using mendelian randomization provides insight into the causal relationships between HDPs and coronary artery disease and ischemic stroke later in life.

An analysis of actigraphy data obtained from the MESA Sleep Ancillary Study indicates irregularities in sleep patterns, particularly in duration and timing of sleep, were linked to increased markers of subclinical atherosclerosis, including increased coronary artery calcium burden.

An analysis of the UK Biobank suggests individuals with celiac disease had an incidence rate of 9.0 CVD cases per 1000 person years compared with 7.4 per 1000 person years in people with no celiac disease.

Given the growing evidence that patients with gout are at an increased risk of developing cardiovascular disease, accurately screening patients and identifying potential risk factors is of critical importance.

The late-breaking findings suggest the potential prognostic benefit of highly purified EPA in patients with chronic CAD with a low EPA/AA ratio.

Announced on May 13, the Onyx Frontier DES carries the same clinical indications as Medtronic's Resolute Onyx DES and will be available in 2.0 mm sizes as well as 4.50-5.00 mm sizes that can be expanded to 6.00 mm.

Data from the DISCHARGE trial provides evidence demonstrating computed tomography could be a safe alternative to catheterization in patients with stable chest pain and suspected CAD.

An analysis of nearly 1000 patients from Spain is providing clinicians with insight into factors that could help predict negative outcomes among patients with stable coronary artery disease.

Deepak Bhatt, MD, MPH, provides perspective on the results of the REDUCE-IT PAD analysis he presented at the American Heart Association 2021 Scientific Sessions.

Arnold Meshkov, MD, explores how discoveries and the advent of new technologies have influenced diagnosis of atherosclerosis throughout history.

Leveraging data from 3 European cohorts, investigators detail the risk of incident coronary heart disease and mortality associated with iron deficiency in the general population.

An analysis of data from the COMPASS study suggests the addition of low-dose rivaroxaban to aspirin resulted in benefits, irrespective of concomitant therapies or comorbidities.

A cross-sectional analysis of data suggests more than 20% of patients with coronary artery disease report experiencing angina at least once a month while 12.5% report experiencing angina daily or weekly.

An analysis of data from 10k women in the Lifetime Risk Pooling Project presented at EPI Lifestyle 2021 suggests premature menopause was associated with a 40% increase in risk of coronary heart disease.

A new analysis of claims data performed by clinicians at Penn Medicine suggests less than 1% of patients with ASCVD initiated therapy with a PCKS9 inhibitor from 2015-2019.

Results of a 305-patient trial indicate ischemic leg pain could serve as a threshold for whether or not a patient with peripheral artery disease will see a meaningful improvement in walking score from their walking routine.

An analysis of more than 1.2 million patients from an STS database suggests women were 14-22% less likely to undergo guideline-recommended revascularization procedures than their male counterparts.

An analysis of data and blood samples from more than 28k women provides insight into the predictive value of more than 50 biomarkers for predicting risk of premature coronary heart disease in aging women.

A randomized trial provides further insight into the effects of intensive lifestyle interventions on coronary plaque progression in patients with nonobstructive coronary artery disease.

An analysis of data from 3 major studies details associations between diets characterized by intake of pro versus anti-inflammatory foods with incidence of cardiovascular disease.