C Difficile Infection

Electroacupuncture also resulted in a greater relief for the majority of OIC symptoms and improved the quality of life for this patient population and had no effects on cancer pain and its opioid treatment dosage.

Patients who were PCR positive or likely colonized in the two-step era were 20 times less likely to be associated with treatment for CDI, without adversely impacting patient outcomes.

FMT was cost-effective compared to vancomycin in both the general CDI population, as well as the subset of patients with IBD. However, it was less cost-effective in compared to fidaxomicin.

There was a 2.35-fold risk increase in PCCRC in the lowest ADR group compared to the highest.

HCV RNA positivity was significantly more prevalent in the male patient than it was for females in both adults and the general population after excluding high-risk groups.

There were no serious adverse events in the group of patients treated with colesevelam.

From new ACG GERD guidelines to the efficacy of colonoscopies, our latest issue addresses topics changing practice and stirring conversation.

A review of changes to clinical, dietary and screening strategies for patients with GERD.

A northern Europe-based trial highlights the potential impact of streamlined and community-supported colonoscopy screening for cancer.

A recent randomized controlled trial showed the limitations of either option, despite being a cornerstone of care.

Analysis from a multicenter, randomized, double-blind, parallel group study comparing the drugs as induction and maintenance therapies in biologic-naïve patients.

There have been only 12 unique studies evaluating this treatment for the primary and secondary prevention of CDI, with only 1 conducted prospectively.

Only 2 of the households sampled featured an owner and pet who both tested positive for C. difficile.

The treatment was well-tolerated, with all serious treatment emergent adverse events considered not related to the treatment.

The results show 2.56% of the CDI group developed prostate cancer, compared to 7.79% in the control group in patients matched by age range and Charlson Comorbidity Index.

Standard infusion group had more patients with P. aeruginosa isolates from blood and respiratory cultures, ICU status at the start of therapy and longer duration of treatment.

The results show adherence to 6 quality indicators was linked to improvements in the post-intervention cohort with significant increases in C difficile testing, CRP testing, testing for latent tuberculosis, thromboprophylaxis, adequate corticosteroids prescription, and limitation of narcotics prescribed.

The results also show a decrease in antibiotic use, hospital length of stay, and overall cost to the patient.

Thus far, the phase 2 data on CP101 was generally positive for the treatment of recurrent C difficile infections.

Older age and use of various medications, including antibiotics, proton pump inhibitors, and corticosteroids were associated with a higher risk of developing C difficile infections.

The 2 strains identified were highly similar and exhibited differences of only 2 single-nucleotide polymorphisms.

SARS-CoV-2 infections cause microbiome dysbiosis in patient and possibly an increase in opportunistic pathogens and a decrease in beneficial bacteria.

The new polymerase chain reaction method was evaluated for specificity, sensitivity, and repeatability using 69 C difficile isolates and 74 fecal samples.

MDR colonization was associated with MDR infection and colonization and infection was linked to higher numbers and duration of antibiotic use.

The company announced they will no longer pursue approval for the treatment despite positive data from recent phase 2 trials.

Patients with COVID-19 and CDI had a higher incidence of sepsis, shock, ICU admission, and acute kidney injuries.

Individuals with level 3 care needs, participants with hypertension or stroke and residents who used canes were at a higher risk of developing norovirus-related diarrhea.

Hospital lengths of stay, costs, and readmissions were all reduced after implementing an antimicrobial stewardship program.

Mattresses, toilet floors, and room floors were places where C difficile was commonly detected in areas inhabited by C difficile infection positive populations.

The number of 30-day hospital readmissions because of CDI increased between 2010-2017.