November 19th 2024
Muvalaplin, an oral treatment, reduced Lp(a) by up to 85% in a 12-week Phase 2 trial presented at AHA 2024.
Fish Consumption and ACS: A Meta-Analysis
March 30th 2015The American Heart Association was one of the first organizations to advocate dietary changes to decrease the risk of coronary heart disease (CHD). The organization's first recommendation appeared in 1957 advising a decrease in the amount of fat intake to decrease atherosclerosis risk. Today, a different approach is recommended, which considers the diet as a whole, with recommendations of what to both include and avoid. Among other nutritional and lifestyle recommendations, the AHA advises the consumption of 2 servings of fish weekly for both men and women.
Testosterone Replacement Therapy Not Associated with Increased Risk of Cardiovascular Events in Men
March 9th 2015Study results show that men with stable coronary heart disease or acute coronary syndrome who received testosterone replacement therapy did not experience higher rates of major adverse cardiovascular events than men who did not receive testosterone replacement therapy.
Medication-Free Strategies Can Prevent Coronary Heart Disease
February 3rd 2015Drug therapy is recognized as an effective way to lower lipids and control hypertension, and for its effect on reducing the incidence of myocardial infarction. However, the impact of personal habits, such as eating, drinking, smoking, and exercise, on the incidence of coronary heart disease without reliance on prescription medications and their potential side effects may be less well established.
How a Maine Program Reduced Heart Disease
Community-wide programs to help residents reduce their risk factors for cardiovascular disease (CVD) have had sporadic success. In rural Maine, however, such an effort has had sustained results lasting over a 40-year period, N. Burgess Record, MD and colleagues report in the Journal of the American Medical Association.
What's the Story with Statins and Stroke Prevention? - A Q&A with Koto Ishida, MD
There have been some disappointing studies and contradictory recommendations on using statins to treat stroke. HCPLive's Gale Scott interviewed Koto Ishida, MD, medical director of the NYU Langone Comprehensive Stroke Care Center, about the implications for clinicians.
Dangerous Liaisons: Elder Abuse and Metabolic Syndromes
December 22nd 2014Around 10% of elders experience some form of elder abuse (physical, sexual or emotional abuse; neglect, exploitation, or abandonment), and elders who are abused appear to have a high level of comorbidity. Evidence suggests that patients who have experienced elder abuse are at higher risk of cardiovascular-related mortality.
Statins for Everyone: Maybe, Maybe Not
December 12th 2014The 2013 American College of Cardiology/American Heart Association guideline for management of low-density lipoprotein cholesterol to reduce atherosclerotic cardiovascular disease risk identified adults who could benefit from moderate- to high-intensity statin use.
Zigzag Calorie Cycling: A Novel Path to Weight Loss
December 3rd 2014Also known as alternate day fasting, "zigzag" caloric cycling calls for the dieter to eat the number of calories required to maintain weight one day, and then 25% of his or her energy needs on the fast day. Studies have shown that individuals who are compliant with this pattern can lose 4% to 8% of their body weight over 8 to 12 weeks.
The Burden of Disease in Homozygous Familial Hypercholesterolemia
November 4th 2014Homozygous familial hypercholesterolemia (HoFH) is a rare and severe hereditary lipid disorder. Patients with HoFH generally have very high serum levels of low-density lipoprotein cholesterol (LDL-C) that is treatment-resistant. HoFH puts affected patients at extremely high risk of premature onset coronary heart disease, and many patients die before they reach their mid-30s.
Bariatric Surgery: Bypass, Band, or Sleeve at 2 Years
November 4th 2014As the number of bariatric surgeries increase, clinicians require more and better data about its long-term outcomes. As we know, as more people take a medication or undergo a surgical procedure, the better the quality of the collective data. It's the strength in numbers concept. In the case of bariatric surgery, many clinicians have questions about treatment failure rates and they suspect that reports of sustained weight loss may be overly optimistic.
Delving Into Adherence With Multiple Sclerosis Therapies
September 16th 2014Adherence is defined as conforming to the recommendations made by the provider with respect to timing, dosage, and frequency of medication taking, and following these recommendations is important for patients with multiple sclerosis (MS) to fully benefit from disease-modifying therapies (DMTs).