Endocrinology

Manufacturers of prescription testosterone products must change their drug labels to include a warning about increased risk of heart attacks and strokes. The labeling change, announced today by the US Food and Drug Administration (FDA) addresses the use of testosterone by men whose decreased level of the hormone is due to aging.

Researchers from the Division of Endocrinology and Metabolism at the University of California, San Francisco analyzed the impact of virtual consultations on the spectrum and volume of endocrine consults. They measured access to endocrine care and downstream health care utilization. Their results indicate that virtual consultation offers many advantages for endocrinologists.

Type 1 diabetes mellitus is an autoimmune disease in which the body destroys all or part of its own roughly 1 billion β cells and cannot regenerate these critical endocrine components. Researchers have turned their attention to immunotherapies for treatment, postulating that targeting the immune system might restore β-cell function. It appears that combination therapies may be needed since clinical trial results have not met expectations based on animal studies.

Multicenter phase II study will also evaluate pharmacokinetics of omega-3 carboxylic acids and omega-3-acid ethyl esters administered to patients with varying degrees of EPI.

Study results show that treatment with atorvastatin lowers LDL-cholesterol levels and reduces the volume of noncalcified and high-risk plaques in HIV-infected patients with subclinical atherosclerosis.

Sanofi's Toujeo (insulin glargine [rDNA origin] injection, 300 U/mL) is a once-daily, long-acting basal insulin product designed to improve glycemic control in adults with type 1 and/or type 2 diabetes.

Among the approximately 382 million people who have type 2 diabetes (T2DM) worldwide, approximately 20% live in South-East Asia and 65.1 million live in India. Asian populations are racially, demographically, culturally and socioeconomically heterogeneous. Researchers have identified unique trends in Asians diagnosed with T2DM.

The most common causes of lipodystrophy are insulin injection, antiretroviral drugs, and hereditary disorders. Some patients with insulin-related lipodystrophy also develop metabolic dysfunction, including insulin resistance, elevated free fatty acids level, abnormal adipocytokine secretion, and ectopic fat deposition.

New research suggests that low testosterone levels in older men are less likely to lead to cardiovascular disease than a sign of underlying problems that are the real cause.

A team from MedUni Vienna has demonstrated that testosterone increases the number of proteins that transport serotonin into the brain.

A review of painful diabetic neuropathy treatments concluded that, while there is no one true effective treatment for all forms of neuropathic pain, many options are still to be explored.

Reports had suggested that mitochondria in adipocytes may potentially have central roles in regulating substrate metabolism, energy expenditure, and the disposal of reactive oxygen species.

Joint inflammation could be reduced in rheumatoid arthritis patients by targeting a specific enzyme, according to research from the Washington University School of Medicine in St. Louis.

Several studies have reported that controlling blood pressure with medication improves cardiovascular outcomes.

The National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) reported that one in 10 American adults had some level of chronic kidney disease (CKD), and that kidney disease is the 9th leading cause of death in the US.

In recent years, growing understanding of diabetes has led to its recognition as a multifaceted disease that cannot simply be dichotomized into its 2 most common subgroups.

A bill before the territory's legislature would fine parents if their children are persistently overweight. Fines could reach as high as $800.

What disorders can give rise to pigmentary changes like this in an obese young man?

Several trials have been conducted, and many more are yet to be completed, that have the goal of addressing whether intensive blood glucose control and intensive blood pressure (BP) control have any long-term benefit on all-cause mortality and major cardiovascular events. Contradictory data have been published with respect to the short- and long-term benefits of aggressive BP and blood glucose control versus conventional treatments for BP and glucose control. This review presents the main points of some of the important trials to date on this subject.

The Food and Drug Administration said Friday it has approved the use of Lucentis (ranibizumab injection) 0.3 mg to treat diabetic retinopathy (DR) in patients with diabetic macular edema (DME).

How valid is the information and advice dispensed by Dr. Oz and other TV doctors?

Hypophysitis is a rare, complex condition in which inflammation infiltrates the pituitary gland. It used to be considered a condition solely affecting peripartum women, but better diagnostics have identified this condition in other patients.

Weightlifting and exercise are beneficial in an educational group for breast cancer survivors, researchers from the University of Pennsylvania determined in a recent study.

Each year, the American Heart Association's (AHA's) Scientific Sessions is the organization's largest yearly gathering of healthcare professionals and researchers in the field of cardiovascular disease and stroke. Providing 5 days of comprehensive education with more than 4000 presentations by world leaders in cardiovascular disease, the AHA 2014 Scientific Sessions featured the results of landmark and long-awaited clinical trials.

Drug therapy is recognized as an effective way to lower lipids and control hypertension, and for its effect on reducing the incidence of myocardial infarction. However, the impact of personal habits, such as eating, drinking, smoking, and exercise, on the incidence of coronary heart disease without reliance on prescription medications and their potential side effects may be less well established.

As electronic health records become more prevalent in the healthcare community, the number of software options doctors can choose from seems to range as widely as the practices themselves.

One day following sigmoidoscopy for an anal stricture, this 61-year-old obese woman was admitted to the emergency department in shock. Earlier that morning, she had a barium enema without evidence of free air inferior to the diaphragm. Acute abdominal pain developed several hours later.

As the National Institute of Health's National Diabetes Education Program (NDEP) institutes a new strategic plan, the group also welcomes a new leader who is familiar with the goals of the program.

The Food and Drug Administration has approved a new medication to improve glycemic control in adults with type 2 diabetes.

This observational cohort study from New Zealand found that "gossipy" magazines are often subtly taken from your waiting room, while the "non-gossipy" magazines remain.