Epilepsy

The FDA has expanded approval for the Embrace smartband to be used by children aged 6 years and older with epilepsy.

Prenatal exposure to the antiepileptic drug valproate is associated with increased risk for ADHD independent of its link to congenital malformations.

Antiepileptic drug levels that remain subtherapeutic—despite the correct dose and proper adherence—can improve with adjustment for pharmacokinetics.

Higher incidences of epilepsy in children with congenital heart disease prompted a neurocardiology team to call for increased perioperative EEG monitoring.

Investigators found significant differences among patient income quartile zip codes, as well as different age cohorts.

A series of newly marketed therapies—from cannabidiol to smartwatches—showed where the future of epilepsy care may grow.

Evidence for dietary, immunological, surgical, and other emerging treatments for pediatric refractory status epilepticus is found to be mostly anecdotal.

A form of artificial intelligence could 1 day be a diagnostic tool for disorders like epilepsy.

Highly-purified cannabidiol (CBD) marketed as Epidiolex can lower the chances of seizures in adults and children with epilepsy.

Patients with epilepsy who live in high crime areas of Chicago had 3 times the rate of seizures as those in low crime neighborhoods.

The ethically dubious physician says he has no regrets. Here’s why.

Children with autism spectrum disorder abnormal EEG results were more similar to children with epilepsy than to children with normal EEG results.

Finalizing a changing diagnosis of an epilepsy syndrome was associated with greater likelihood of a sustained seizure-free period, a new study has found.

If CVS and Aetna are truly charting the future of healthcare in this country, then it’s long past-time that their actions align to their rhetoric.

In this retrospective study, 18.5% of children became drug-free while on the ketogenic diet.

Outcomes with lacosamide monotherapy for focal seizures in real-world practice were similar to clinical trials but varied with antiepileptic drug history.

Research into epilepsy and HRV has been ongoing for more than 30 years, so why hasn’t it been integrated into clinical practice?

Ezogabine was not marked as an antidepressant but seemed to be an effective treatment in a small study.

Seizures were well controlled for up to 6 years in some patients with epilepsy receiving perampanel for partial onset seizures.

Eslicarbazepine in combination with lamotrigine is better tolerated than when combined with carbamazepine for focal seizures.

Levetiracetam found superior to carbamazepine and valproate sodium in reducing Rolandic discharges on EEG of children with Rolandic epilepsy.

Cannabidiol (Epidiolex), the first FDA-approved plant-derived cannabinoid medicine in the United States, is now available by prescription for patients with seizures associated with Lennox-Gastaut syndrome or Dravet syndrome.

Aquestive Therapeutics’ clobazam (SYMPAZAN) oral film has been approved by the US Food and Drug administration (FDA) for the treatment of seizures associated with Lennox-Gastaut syndrome (LGS) in patients aged 2 years or older.

This approval marks the first and only oral film approved by the FDA for the treatment of seizures associated with Lennox-Gastaut syndrome.

In absence of head-to-head trials between 2nd and 3rd generation antiepileptic drugs, a meta-analysis was used to identify suitable agents for monotherapy.

Other risk factors included the age of conception, with women younger than 18 or older than 37 being at greatest risk.

Switching antiepileptic drug manufacturer was found to increase the risk of seizure recurrence in a German population, contrary to findings in the US.

The effect of a carbapenem on VPA is significant and may result in reduced efficacy and increased seizure activity. Because of the mechanism of this interaction, increasing the dose of the VPA will unlikely achieve therapeutic plasma concentrations.

Investigators used EHR data to identify epilepsy patients at risk for obstructive sleep apnea and refer them for polysomnography.

Outcomes can worsen for pregnant women with epilepsy when antiepileptic drug concentrations fall below 65% of preconception amounts.