Geriatrics

In older patients receiving medication intensification, no differences were seen in the risk of severe hyperglycemia, severe hypoglycemia, or death at 1 year.

In research presented virtually at IDWeek 2021, investigators with the US Centers for Disease Control and Prevention conducted a review of nursing home antibiotic stewardship citation deficiencies in order to improve implementation.

Age, antibiotic use, and proton pump inhibitor use was associated with an increase in C difficile infections.

RT001 and RT176 were the most prevalent C difficile ribotypes found from C difficile isolates using PCR testing.

A total of 269 participants were considered potentially overtreated, while 109 participants were appropriately on target, and 56 participants potentially undertreated.

The machine learning model outperformed a comparison logistic regression model in identifying high-risk patients for HBV.

CDI rates remained down in 2020 despite an increase in antibiotic use during the pandemic.

There were 4 errors found involving wrong medications or injections in the wrong eye at KPNC in 2019 and 2020.

Older individuals are at an increased risk of more severe COVID-19 outcomes.

Trigger avoidance-only strategies don’t actually help migraine patients improve. These are the proactive behaviors that do.

Research suggests that men and women of all ages in mainland China recorded similar results of untreated osteoporosis and vertebral and clinical fractures, all of which are becoming more prevalent over time.

Data show skeletal muscle relaxant associated with increased risk of fall-related injury (OR 1.28) and all-cause hospitalization (OR 1.11).

Higher depressive and manic (symptoms were associated with lower GAF, most strongly among the older participants.

It’s time to stop just recommending trigger avoidance strategies to patients. These are the proactive behaviors that will actually help improve migraine.

Previous research has shown that COVID-19 can impact ocular health.

Metabolomic and preclinical studies have indicated that branched-chain amino acids may protect against neurodegenerative diseases.

While the nerve disease is not life threatening, patients may experience considerable poor quality of life and emotional distress.

Patients included in the high-dose group demonstrated statistically significant improvements compared to placebo for MDS-UPDRS total score.

Nearly half of all never C difficile cases are found in nursing home communities.

The overall 90-day cumulative incidences of a first CDI episode was 1.9%.

The risk was generally did not depend on whether the initial fracture was deemed traumatic or nontraumatic.

A new Polish study calls for greater focus on asthma and the link to delirium in older patients, who may face greater mortality risk.

The approval for Biogen’s disease-modifying, anti-amyloid agent aducanumab follows a long regulatory journey.

Patients treated with ustekinumab had significantly more prior biologic use than patients treated with vedolizumab.

A large proportion of HCV patients remain undiagnosed, particularly in the older population.

Older patients who maintained the multi-domain rehabilitation program saw improvements in various markers of physical function.

Females and older patients had higher rates of hospitalizations with CDI than males and younger patients.

An FDA-approved device, provided to eligible patients with age-related macular degeneration, showed ability to detect CNV risks over 5 years.

Late life depression is a known risk factor for dementia, impacting 8-16% in the US.

The study presented at the 2021 AAN Meeting follows the complete response letter issued by the FDA to Acadia Pharmaceuticals due to deficiencies in their sNDA.