Major Depressive Disorder

Only 3.03% of the SPI group reported suicidal behaviors, compared to 5.29% of those receiving usual care during the 6-month follow-up period.

An analysis of pediatric ICU interactions found that physicians are far more likely to get a beneficial response from families when they show empathy to their emotions.

Previously, the benefit of exercise in mediating both CVD and depression was documented, but the association between midlife fitness with later depression and death from heart disease had not been.

An NYU study showed that physicians at small, independent primary care practices report much lower rates of burnout—13.5% compared to the 54.4% national average.

People of good conscience, including many physicians, are sharply divided on the ethics of MAID/PAS. Unfortunately, much of the support for this practice is founded on several myths and misconceptions regarding existing MAID laws and practices, according to Ronald Pies, MD.

A study of low-income mothers found that participants who experienced problem-solving sessions reported 11% lower stress compared to controls.

People living with mental illness face great adversity. One of their greatest challenges is the seemingly intractable problem of stigma.

Cannabidiol (Epidiolex) is the first drug containing a marijuana-derived substance to receive FDA approval.

Though the rate of suicidal ideation in pediatric patients with T1D is not significant from general population, girls reported twice as frequent rates.

An interactive parent-child therapy appears to reduce depression in children 3-6 years old. Interestingly, the therapy also improved symptoms of clinical depression in participating parents.

Between 2013 and 2016, diagnoses of major depression jumped by 33% overall, and by 63% and 47% among adolescents and millennials, respectively.

A national discussion on a public health crisis is slowing down before it can even really start — again.

Researchers found that patients with depression were at increased risk of cognitive decline long before dementia could be diagnosed.

The therapy's currently-planned phase 3 trials for major depressive disorder, postpartum depression disorder are being converted into pivotal studies after a meeting with the FDA.

Depression in men–but not women–reduces the chances of pregnancy for infertile couples, a new study suggests.

The CDC reported that suicide rates have increased by at least 30% in half of all US states.

The therapy, when combined with oral antidepressant, reported a 70% reduction in relapse risk for depression versus standard-of-care.

The solution from Sage Therapeutics may become the first treatment indicated for women with postpartum depression.

The youths’ perception of discrimination was related to a higher risk of MDD over the course of 30 days, then at 12 months, and then over the course of their lifetimes.

Response to ketamine treatment in mood disorders may be better predicted based on baseline cognitive impairment.

Analyzing post-mortem brain tissue of subjects with major depressive disorder, researchers found that 52 genes were expressed differently in women and men.

The use of the popular smartphone application Pokémon GO—and possibly similar games—could have potential therapeutic benefits for those with mental illness.

If approved, therapy would be the first of its kind to target Glx for the treatment of bipolar depression.

The mean level of anxiety has increased 5 points since 2017 on a 100-point scale, with Baby Boomers reporting a 7-point jump over the last year.

The drug is approved for adults with depression, but exceptionally high placebo responses rendered its effects in children not statistically significant.

Women who continued using antipsychotic medications during pregnancy had an absolute risk of 4.2% to 12% of developing gestational diabetes.

Patients that had their medication selection guided by the GeneSight pharmacogenomic testing were 50% more likely to achieve remission and 30% more likely to achieve treatment response.

John Greden, MD, discussed the challenges physicians face in diagnosing, identifying, and treating depression, and the populations that are still severely underserved.

Darrell Kirch, MD, spoke at the APA’s annual meeting about the impact physician burnout has had and what can be done to address it and to improve clinician well-being.

Firearm use in the not guilty by reason of insanity population is more closely related to substance use and personality disorder than psychotic or mood disorders.