The HCPLive Infectious Disease condition center page is a comprehensive resource for clinical news and insights on respiratory health. This page consists of interviews, articles, podcasts, and videos on the research, treatment and development of therapies for asthma, COPD, interstitial lung disease, COVID-19, and more.
December 9th 2024
In this month's episode of Lungcast, Jacob Sands, MD, discusses the American Lung Association’s recently newly-released 2024 State of Lung Cancer report.
Infant Gut Bacteria May Reveal Asthma and Allergy Risk
Previous studies have shown that “the gut microbiota differs in composition and diversity during the first months of life in children who later do or do not have allergic disease," but researchers who focused on immunoglobulin A prevalence made a different finding.
Pros and Cons of Electronic Monitoring Devices for Inhaler Adherence
The pros identified included the possibility of EMDs improving adherence, that the devices might help motivate patients through creating a sense of independence and accountability, and that the data generated could help in building a trusting relationship between clinician and patient.
Researchers Identify Factors in Asthma Severity Variance
Using data from the Inner-City Asthma Consortium, researchers were able to identify the factors that contribute to more than half the variance in asthma severity, including allergic sensitization and, significantly, environmental tobacco smoke.
Researchers Examine Biologic Use for Severe Asthma
Only 5-10% of asthma sufferers have "severe" asthma, but account for about 50% of the social cost of the disease. The current focus in research is on finding therapies to treat specific components of the inflammation.
Bringing Together Big Data and the Scientific Process to Treat Asthma
A new article in the Journal of Allergy and Clinical Immunology argues that genetic studies of asthma, expected to be game-changers, have “delivered neither meaningful clinical diagnostic tools nor useful insights into disease pathogenesis.â€
Life at the Corner of Asthma and Insomnia
A study out of the University of Pittsburgh identifies significant comorbidity and negative outcomes in those with insomnia and asthma, and finds that even asthmatics who report no nighttime breathing disturbances still face a predisposition to sleeplessness.
Corticosteroid Success Linked to Differences in Bronchial Microbiome
December 7th 2016Individuals with atopic asthma were recently found to have a distinctive bronchial bacterial microbiome that not only differs from those without asthma, but between asthmatics with phenotypes more responsive or resistant to inhaled corticosteroids.
Meta-Analysis Asserts Link Between Traffic Pollution and Childhood Asthma
Studies that found no connection are outliers, the authors of the new meta-analysis write. They believe the findings have been consistent enough to assert a certain link between pollution exposure and juvenile asthma, but they note that many important questions remain.
AerobiKa Device Well Tolerated in Children with Asthma, but Disease Scores Unaffected
AerobiKa, a vibratory positive expiratory pressure device meant to reduce mucus plugging, “did not demonstrate statistical significance in terms of improved clinical asthma score or reduced hospitalization rate.â€
Discontinuing Omalizumab Can Exacerbate Asthma
November 22nd 2016Patients who discontinued long-term treatment with omalizumab (Xolair/Genentech and Novartis) were more likely to experience an episode of severe asthma exacerbation during a one-year monitoring period than those who continued the treatment, in a recent study to determine whether therapeutic effect persists after discontinuation.