Algae-Based Injectable Implant Device Improved Heart Function
Injecting globs of a biopolymer based on brown algae into the heart muscle of patients with advanced heart disease helped halt or reverse disease. The procedure is meant to thicken the ventricle wall. That reduces pumping stress.
Novel Reversal Agent Found Effective
An investigational drug called andexanet alfa that can reverse the anticoagulant effects of FXa inhibitors met all primary and secondary efficacy endpoints, researchers said in a late-breaking clinical trial report at the AHA meeting in Orlando.
Evaluating the Risk/Benefit Profile of Ticagrelor
November 10th 2015Analysis of data from the PEGASUS-TIMI 54 trial showed high rates of treatment discontinuation due to adverse events such as bleeding and dyspnea, with the highest rate occurring in the first year of treatment. Patients who stuck with treatment experienced a reduction in cardiovascular death, myocardial infarction, and stroke.
PROACT-4 Trial on Benefits of Troponin Testing for Acute Cardiovascular Disease
November 10th 2015Chest pain is one of the most common reasons that patients visit the emergency room, and the use of troponin testing can help cut down the time between first medical contact to final patient disposition.
OK to Give tPA to Stroke Patients on NOACs
Intravenous administration of tissue plasminogen activator (tPA) appears safe in selected patients who were already on novel oral anticoagulants (NOACs) a team reported at the American Heart Association Annual Scientitific Session in Orlando, FL.
CHA2DS2-VASc Scores Useful Even When Patients Do Not Have Atrial Fibrillation
The scoring system known as CHA2DS2-VASc is commonly used as a clinical guideline for assessing ischemic stroke risk in patients with atrial fibrillation (AF). A research team from Santiago, Chile found it can also predict vascular dysfunction and cardiovascular events in high-risk patients who do not have AF.
Can Telomere Length Predict Stroke Risk?
Independent of cardiac risk factors, including chronological age and blood pressure preserved telomere length "represents healthy cellular aging," Dhananjay Vaidya and colleagues at Johns Hopkins University reported in an abstract.
No Evidence HPV Vaccine Causes CRPS or POTS in Young Women
A committee of the European Medicines Agency has completed a long-anticipated review finding no evidence that human papillomavirus (HPV) vaccines trigger complex regional pain syndrome (CRPS) or postural orthostatic tachycardia syndrome (POTS).
Pathology Between Gout and Cardiovascular Events Remains a Mystery
The presence of urate crystal precipitation does not necessarily indicate a greater risk of cardiovascular complications for patients with increased levels of monosodium urate, which is the defining characteristic of gout.
ATRIA Score Accurately Identifies Patients at Low Risk for Stroke
A new tool for assessing the risk of thromboembolic events in patients with atrial fibrillation performed better than the existing standard in a large retrospective analysis. ATRIA risk scores were less likely than CHA2DS2-VASc scores to mistakenly characterize patients as "high risk" and, therefore, to lead to the overuse of anticoagulation.