Quitting Smoking, Not Cutting Back, Linked to Better Lung Health
Smokers who quit had lower disease risk than the group identified as stable, low-rate smokers.
Dupilumab Manages Asthma Symptoms, Reduces OCS Dosing in QUEST, VENTURE Trials
Sanofi and Regeneron reported promising results from a pair of pivotal phase 3 trials for the investigative add-on therapy.
Socioeconomic Status, Racial Disparity at the Heart of US Pollution
From food deserts to hazardous jobs that inhibit exposure and limit the means to prevent it, people of low SES are at greatest environmental health risk.
Prenatal Vitamin C Can Protect Infants' Lungs from Mother's Smoking Habits
Researchers intend to follow observed infants into early childhood to gauge the vitamin's influence on pediatric asthma rates.
Acute Blood Allergy Testing Associated with Fewer Pediatric Asthma Hospitalizations
Children given immunocap radioallergosorbent tests when hospitalized for asthma avoided re-hopsitalization twice as long as children not given the test.
Flavonoids May Slow Lung Function Decline Specifically in Never, Ex-Smoker Population
A type of flavonoid found in dark-pigmented fruits like red grapes and blueberries may slow the lung function decline that occurs with aging.
Fluticasone Furoate Gets FDA Approval for Pediatric Asthma Maintenance
The inhaled corticosteroid from GSK is indicated for pediatric asthma patients aged 5-11 years old.
Mediterranean Diet Limits Deaths Associated with Pollution Exposure
Older people adhering to the antioxidant-rich diet were less likely die from cardiovascular conditions when exposed to greater ambient air pollution.
Mepolizumab COLUMBA Study Reports Consistent 3-Plus Year Benefits
The monoclonal antibody reported quick and consistent exacerbation rate reduction in patients with severe eosinophilic asthma.
Trelegy Ellipta IMPACT Results Bolster Results Versus Dual Therapies
The once-daily, triple-drug inhaler therapy reported improvements in exacerbation rate and risk to first event.
Multidisciplinary Pulmonology Clinic Improves Low-Income Patient Access
Over 16 months, a greater rate of patients reported returning visits, proper inhaler use understadning, and overall satisfcation.
Inpatient Opioid Use May Increase Outpatient Opioid Prescription Use
Reducing use of opiates near the end of hospital stay, especially 24 hours prior to discharge, may reduce outpatient prescription of opioids.
In Utero Household Air Pollution Exposure Increases Infants' Risk of Poor Lung Function
Infants whose mothers were exposed to carbon monoxide in the second and third trimester were at highest risk for reduced lung function when they were tested at 1 month of age.
CPAP Shows Heart Rate Reduction for OSA Patients with Prediabetes
The therapy showed reduction in nighttime resting heart rate comparable to that of beta blockers.
Increased Risk of Asthma Development Linked to Ozone Exposure at Birth
The hazard ratios for ozone measured at bone as a single pollutant showed statistically significant higher risks for development of asthma, allergic rhinitis and eczema.
Are Inhaled Statins a Viable Option for Asthmatics?
Simvastatin may reduce inflammation, fibrosis, bronchial constriction, mucus
What Is Asthma/COPD Overlap Syndrome?
Doctors need to conduct clinical trials and define the disease.
How Does Obstructive Sleep Apnea Affect Arterial Inflammation?
Neomi Shah, MD, MPH, studied patients with sleep apnea to uncover its effect on arterial inflammation.
Can Simvastatin Prevent Delirium in Ventilated Patients?
Valerie Page, MB, BCh, FRCA, recounts a study of simvastatin on delirium patients.
Prenatal Pollution Exposure and Asthma Development in Children
How Mepolizumab Helps EGPA Patients
Michael Wechsler, MD, MMSc, recounts the phase III trial of Mepolizumab on patients with eosinophilic granulomatosis with polyangiitis (EGPA).
Mepolizumab Reduces Remissions in EGPA Patients
Drug meets all primary and secondary end points in phase III study.
Revefenacin Continues to Show Lung Function Improvements for COPD
Revefenacin improved trough FEV1 versus placebo in two phase 3 trials for COPD.
Benralizumab Highly Effective for Severe Asthma
Benralizumab led to a 75% reduction in the use of oral corticosteroids for severe asthma.
PBI-4050 Slows FVC Decline in Idiopathic Pulmonary Fibrosis
PBI-4050 slowed or stopped declines in lung function in patients with IPF.
Fluticasone Furoate/Vilanterol Reduces Night-Time Awakenings in Asthma Patients
Asthma patients woke up less often and improved faster with FF/VI
Ambulatory Oxygen Improves Health Status in ILD Patients
Ambulatory oxygen improved symptoms, performance, and recovery time in fibrotic ILDs.
P2X3 Inhibitor Effectively Reduces Frequency of Chronic Cough
MK-7264 reduced cough frequency by 37% for patients with chronic cough.
Immune Biomarkers May Predict Survival for Patients With IPF
ICOS and CD28 expression levels on CD4 T cells effectively predicted survival for patients with idiopathic pulmonary fibrosis.
Antibiotic Therapy Fails For a Quarter of Adults with Pneumonia
Older patients and sick patients are at increased risk.