News

Research has established that various parts of the trigeminal system are responsible for peripheral symptoms of migraine. Treatment with corticosteroids reduces the symptoms of migraine, but the treatment is associated with long-term side effects.

Ambrisentan and tadalafil as one lowers risk of clinical failure in patients with pulmonary arterial hypertension.

Early diagnosis continues to be one of the biggest challenges associated with rheumatoid arthritis (RA); however, researchers have identified a genetic marker that can predict tissue damage severity that could lead to better treatments.

Specialists agree that a condition unofficially known as asthma-COPD overlap syndrome (ACOS) exists, according to a survey completed by Marc Miravitlles, MD, and colleagues. The participants were 26 specialists in either asthma or chronic obstructive pulmonary disease (COPD practicing in Spain. They first completed a structured questionnaire, and then attended an in-person work meeting that followed the Metaplan technique.

People with pulmonary arterial hypertension may benefit from initial combination therapy with ambrisentan and tadalafil, according to a recent study published in the New England Journal of Medicine

Close relatives or friends often serve as surrogate decision-makers for patients in intensive care units. Physicians are usually comfortable answering their medical questions. But what happens when spiritual or religious issues arise in the context of end-of-life decisions?

New research on the link between diabetes and pancreatitis has shown a strong association between the severity of pancreatic dysfunction and subsequent risk of developing type 2 diabetes mellitus.

Women seek medical care more frequently than men after treatment for asthma in the emergency department, according to findings published in the Annals of Allergy, Asthma & Immunology.

The US Food and Drug administration today issued a warning that the type 2 diabetes medicines sitagliptin (Januvia/Merck) linagliptin (Tradjenta/BI), and alogliptin (Nesina/Takeda) "may cause joint pain that can be severe and disabling."

Ebola can persist in wastewater, plastic, and steel and the virus has even gone undetected in a blood test. But how many physicians are actually prepared to properly assess a patient with a potential case of the deadly disease? A team from the Massachusetts General Hospital (MGH) found that physicians least likely to encounter patients with Ebola were more likely to use excessive approaches.

A long-term study of alemtuzumab for treatment of Behçet disease (BD) yields promising evidence that the monoclonal antibody can successfully treat refractory and relapsing courses of the disease.

Stress resulting from frequent migraine headaches may contribute to the development of medical and psychological comorbidities that can result in an ugly cycle of more migraines, according to a study in the Journal of Pain Research.

Two comprehensive reviews in the Indian Journal of Psychiatry looked at the use of pharmacologic therapy for psychiatric conditions during pregnancy and lactation. One review looked at mood stabilizers and the other focused on antidepressants, anxiolytics, and hypnotics.

A Japanese study suggests that parental bonding style during childhood is associated with the prevalence of chronic pain in adults in the general population and that the association is more robust for paternal bonding than for maternal bonding.

Three recent studies – in three very different publications – add to a growing cache of evidence showing that music can have significant benefits for patients with pain.

Patients suffering from psoriasis have a higher risk of developing arrhythmia – even after controlling for other risk factors, according to a study published in the Journal of the American Academy of Dermatology.

Reproducing study results can be difficult in any scientific field, but a study in the journal Science showed that confirming research in psychology is particularly challenging.

While a common method used to treat low back pain may provide immediate relief, its effects do not extend for a substantial period of time, a new analysis has found.

Consistently using low-dose aspirin and non-aspirin non-steroidal anti-inflammatory drugs (NSAIDs) could successfully diminish the risk of colorectal cancer (CRC) – the third most common cancer in the US.

The US Food and Drug Administration last night announced it has approved evolocumab (Repatha/Amgen), an injectable drug for some patients who are unable to get their LDL cholesterol under control. Statins are a cheaper and generally effective treatment, but the new class of drugs is expected to help people who cannot tolerate them, for whom they do not work, and for people with heterozygous familial hypercholesterolemia.

Researchers report that nearly one in four patients with hepatitis C are denied initial approval for treatment.

Yoga has shown to improve heart health and benefit patients with rheumatoid arthritis. Even those with breast cancer have gotten in on the action. A new study in Evidence-Based Complementary and Alternative Medicine provides evidence that yoga offers progressive beneficial anti-stress benefits to members of a prison population.

A recent review in Chronic Wound Care Management and Research suggests that wound pruritus is not well understood and is often poorly treated, despite nearly a century of clinical investigation. Irritations of the skin can be as distressing for patients as pain, the authors noted; yet, there is no established treatment protocol for wound pruritus.

A new study in Nutrition Journal shows that patients suffering from systemic lupus erythematosus (SLE) demonstrated significant improvement by taking fish oil supplements.

The US Food and Drug Administration approved a new glycemic control treatment for type 2 diabetes for adults, a combination product made of empagliflozin (Jardiance/ Boehringer Ingelheim) and metformin hydrochloride. It will be marketed as Synjardy in a joint venture with Eli Lilly.

A new review and meta-analysis finds that - despite the lack of drug-specific antidotes to arrest major bleeds - novel oral anticoagulants are associated with a lower risk of fatal bleeds than warfarin in patients with atrial fibrillation.

Mobility is great. Hypermobility? Less great. In the joints, hypermobility leads to musculoskeletal pain – and often times, lots of it. A recent review in the Journal of Pain Research outlined several of the challenges in treating generalized joint hypermobility (GJH) and found many difficult questions and few easy answers.

The US Food and Drug Administration (FDA) updated labeling for rilpivirine, marketed under the name Edurant, for the treatment of the human immunodeficiency virus (HIV). The changes have been made in the dosage and administration, warnings and precautions, adverse reactions, and clinical information sections.

Recent study results suggest Internet-based cognitive behavioral therapy (ICBT) could be useful for adolescents with anxiety disorders along with standard treatment delivered in child and adolescent psychiatric clinics.

Researchers seek to determine whether depression subtype is an useful predictor of which medication regimen might be most effective in treating patients with those subtypes.