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The signs and symptoms of rheumatoid arthritis were improved at 3 months after various doses of the JAK 3 inhibitor decernotinib were administered.

Mouse models of multiple sclerosis were able to halt disease progression after targeting the nucleus of inflammatory cells.

Obesity rates have climbed nearly 50 percent since 1997, with as much as 30 percent of the population classified as obese. There is strong belief within the health care industry that obesity should be treated as a primary medical condition, with physicians playing a major role. Evidence suggests that patients are more likely to lose weight when they are advised by their primary care physicians to do so.

Analysis of data from a previous study indicates that opioid use may increase the risk of heart attack by triggering atrial fibrillation.

Research indicates that, despite the relative simplicity of dabigatran regimens, physicians and pharmacists must follow up with patients repeatedly to maximize the chances they'll adhere to prescriptions.

University of Toronto researchers have found a novel role for a cell membrane-anchored mediator in cancer pain. They suggest that the serine protease TMPRSS2-a gene previously shown to play a key role in some of the most aggressive forms of androgen-fuelled cancers-appears to be the trigger behind the most severe forms of cancer pain.

Boehringer Ingelheim announced Tuesday the US Food and Drug Administration (FDA) approved once-daily Stiolto Respimat (tiotropium bromide and olodaterol) Inhalation Spray to treat airflow obstruction in patients suffering from chronic obstructive pulmonary disease (COPD), including chronic bronchitis and/or emphysema.

People with a rare inherited condition known as "congenial insensitivity to pain" (CIP), which makes it impossible for them to feel pain, may hold the answer to providing pain relief for patients suffering with chronic pain.

GLP-1 receptor antagonists have been associated with thyroid cancer in rodents, and in fact carry a boxed warning about the potential for cancer in humans. This leads many clinicians to ask if they should be concerned about using these drugs in patients who have or develop specific types of thyroid cancer

Dementia is linked to comorbid diabetes and psychiatric conditions like depression, according to research from University College London.

Seizures and other neurological problems traced to pork tapeworms are a new health threat for the US, the CDC reports.

A recent study examined the cost of biologic and non-biologic DMARDs under Medicare Part D and stand-alone coverage plans.

A salmonella outbreak traced back to sushi made with raw tuna has infected a total of 53 individuals so far.

Early diagnosis and treatment is the key to preventing long-term joint damage in patients with psoriatic arthritis.

Sitagliptin appears to have beneficial systemic and adipose anti-inflammatory effects in combination antiretroviral therapy-treated HIV-positive adults with impaired glucose tolerance. The drug may prevent cardiovascular problems by reducing inflammation linked to heart disease and stroke in this patient population.

Achillion Pharmaceuticals has joined forces with Janssen Pharmaceuticals to develop a short-duration oral regimen to treat chronic hepatitis C, the companies announced.

The results of the largest study of its kind to date indicate that new antipsychotic medications-including quetiapine, olanzapine, and risperidone-do not appear to put women at additional risk of developing gestational diabetes, hypertensive disorders, or major blood clots that obstruct circulation, all conditions that often develop during pregnancy or with the use of older antipsychotic medications.

Stiff and swollen joints may land some relief due to a newly discovered anti-inflammatory chemical compound.

Fatal drownings happen even in strong, healthy swimmers in lifeguarded pools. A New York City health department investigation points to an under-reported cause: deliberate breath-holding as part of informal contests or self-imposed training regimens.

In addition to causing pain and discomfort and requiring antibiotics, a Danish study revealed that infections can negatively affect cognitive ability.

The FDA says the investigational drug combination of daclatasvir (Daklinza/ Bristol-Myers Squibb) and sofosbuvir (Sovaldi/Gilead ) may now be given to patients who have hepatitis C infections with either advanced cirrhosis or infections that have come back after patients received a liver transplant.

The US Food and Drug Administration today approved 3-month paliperidone palmitate (Invega Trinza/Janssen) a longer-lasting version of Janssen's paliperidone palmitate product marketed as Invega Sustenna, a treatment that works for only 1 month per injection.

Preventing the replication of the hepatitis C virus (HCV) may be a future reality thanks to an important exploration.

Antibiotic resistance is a worldwide threat with potentially disastrous consequences. In the wake of a recent report claiming Salmonella is becoming less sensitive to medication, a new study shows how misdiagnoses are contributing to the growing problem.

In the US, there is a relationship between the weather and West Nile virus (WNV) disease prevalence-which could be used to forecast outbreaks-according to an article published in The American Journal of Tropical Medicine and Hygiene.

With a new study showing that 4 out of 10 US adults know someone who has battled prescription painkiller abuse during the last 5 years, concerns about the rising epidemic are more prominent than ever.

Historically, surgical times were tracked to help operating suite managers schedule operating rooms. For the last 25 years or so, quality managers have watched surgical times with respect to patient outcomes. They've come to a growing realization that faster is not always better and slower may not represent careful, deliberate technique.

Researchers in the US and Sweden recently reported that coffee consumption in the years prior to multiple sclerosis symptom onset has a significant protective effect.

Cases of prescription opioid misuse, abuse, and addiction are still on the rise, claiming thousands of lives each year.

Cruise ships are not the only place where vacationers can get the dreaded norovirus. A US Centers for Disease Control and Prevention report today documents an outbreak in a recreational lake in Oregon and warns that swimming in lakes can be hazardous.