Clinical Quiz: Nonstatin Therapies for LDL-C Lowering

Author(s):

Key Takeaways

Statins are essential for LDL-C management, but intolerance requires alternative approaches for dyslipidemia treatment.
Bempedoic acid and ezetimibe combinations are effective non-statin therapies for patients intolerant to statins.
The 2022 ACC Expert Consensus Decision Pathway offers guidance on non-statin therapies for managing atherosclerotic cardiovascular disease risk.

This clinical quiz will test your knowledge on the use of non-statin therapies for LDL-C lowering based on the American College of Cardiology's 2022 Expert Consensus Decision Pathway on the Role of Nonstatin Therapies for LDL-Cholesterol Lowering in the Management of Atherosclerotic Cardiovascular Disease Risk.

In LDL-C management, statins have remained a cornerstone of care since their advent decades ago. However, despite mountains of data demonstrating class's profound effect on LDL-C lowering and favorable safety profile, many patients are statin-intolerant and require a more nuanced approach to the management of their dyslipidemia.

Decades ago, this presented a major issue for some, but, in recent years, addition of new therapies, including bempedoic acid and combination with ezetimibe, have proven to be reliable options for these patients. In this clinical quiz, we test your knowledge on use of non-statin therapies for lowering LDL-C based on the American College of Cardiology's 2022 Expert Consensus Decision Pathway on the Role of Nonstatin Therapies for LDL-Cholesterol Lowering in the Management of Atherosclerotic Cardiovascular Disease Risk.

Which of the following is NOT considered a nonstatin therapy for LDL-cholesterol lowering?

References:

Writing Committee, Lloyd-Jones DM, Morris PB, et al. 2022 ACC Expert Consensus Decision Pathway on the Role of Nonstatin Therapies for LDL-Cholesterol Lowering in the Management of Atherosclerotic Cardiovascular Disease Risk: A Report of the American College of Cardiology Solution Set Oversight Committee [published correction appears in J Am Coll Cardiol. 2023 Jan 3;81(1):104]. J Am Coll Cardiol. 2022;80(14):1366-1418. doi:10.1016/j.jacc.2022.07.006