Opinion

Video

Treatment Response to PPAR Agonists and Other Therapies in PBC

Key Takeaways

  • PBC involves autoimmune-mediated destruction of intrahepatic bile ducts by autoreactive T lymphocytes, leading to cholestasis.
  • Accumulation of toxic bile acids due to cholestasis causes hepatocellular damage and inflammation.
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The panel of experts discuss how to determine the effectiveness of treatment in primary biliary cholangitis (PBC), focusing on key clinical markers, biochemical responses, and patient outcomes.

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