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GOLD 2025 Report: Addressing Heart Disease in COPD

Panelists discuss how the coexistence of heart disease and chronic obstructive pulmonary disease (COPD) requires careful management as these conditions significantly impact each other. In stable COPD, cardiovascular complications are a leading cause of mortality, whereas acute exacerbations can worsen heart function. Key treatable traits in COPD-associated pulmonary hypertension include hypoxemia, inflammation, and right ventricular dysfunction. Management focuses on optimizing respiratory and cardiac function through appropriate medication selection, oxygen therapy when indicated, and careful monitoring of both conditions to prevent deterioration.

Video content above is prompted by the following:

  • Why is appropriate treatment of heart disease important in COPD? What are key considerations regarding those with stable COPD and those with acute exacerbations?
  • What are some of the “treatable traits” associated with pulmonary hypertension in COPD, and how should patients be treated?
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