Role of LDL-C in ASCVD

Author(s):

Key Takeaways

LDL-C is a key contributor to ASCVD by promoting plaque formation in arterial walls.
Lifestyle factors like poor diet, inactivity, and smoking elevate LDL-C levels.
Genetic predispositions, such as familial hypercholesterolemia, significantly impact LDL-C levels.
Effective ASCVD prevention and treatment require understanding both lifestyle and genetic influences on LDL-C.

Panelists discuss how elevated LDL-C levels significantly contribute to ASCVD development through both modifiable lifestyle factors and genetic predisposition, making it a critical target for cardiovascular disease prevention.

EP: 1.Prevalence of Cardiovascular Disease

EP: 2.AHA Guidelines and Patient Mortality

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EP: 3.Role of LDL-C in ASCVD

EP: 4.Pediatric Lipid Screening

EP: 5.Lp(a) in Pediatrics

EP: 6.DCRM Recommendations for Lipid Testing and LDL-C Management

EP: 7.Other Lipid Biomarkers

EP: 8.LDL-C Management in Subpopulations

EP: 9.Cost Considerations for LDL Reduction Therapies

EP: 10.Familial Hypercholesterolemia Testing

EP: 11.Role of Lp(a) in ASCVD Risk

EP: 12.Data Analysis: State of LDL-C Control in Patients With ASCVD

EP: 13.Pediatric Lipid Treatment Recommendations

EP: 14.International Lipid Expert Panel Recommendations and RACING Trial

EP: 15.SPORT Trial

EP: 16.Novel Nonstatin LLTs for Lowering LDL-C and CVD Risk

EP: 17.CLEAR-Outcomes Data: Primary Prevention With Bempedoic Acid

EP: 18.Barriers Associated With Controlling LDL-C

EP: 19.Final Insights

Video content above is prompted by the following:

What role does low-density lipoprotein-C (LDL-C) play in ASCVD?
What lifestyle and genetic factors contribute to developing high blood levels of LDL-C?