Gale Scott

Intravenous administration of tissue plasminogen activator (tPA) appears safe in selected patients who were already on novel oral anticoagulants (NOACs) a team reported at the American Heart Association Annual Scientitific Session in Orlando, FL.

Blocking IL-23p19 with an investigational Boehringer-Ingelheim compound called BI 655066 got better results than ustekinumab (Stelara/Janssen) in patients with moderate to severe plaque psoriasis

Other than joint replacement, not much works in treating osteoarthritis of the knee. A Brazilian research team said it has had success with intra-articular injections of ozone.

A biologic agent called SB5 worked as well adalimumab,researchers reported at the American College of Rheumatology meeting in San Francisco, CA.

Heart disease is the number one killer of US women, but a national survey found cardiovascular health is not on most women's radar.

For overweight adults with type 2 diabetes, study results show that even light walking was linked to an average 10-point drop in blood pressure.

There are many anti-thrombotics available. An industry study showed apixaban had the best record of dissolving clots without causing major bleedign.

Tissue plasminogen activator (tPA) can dissolve lethal clots in the lungs but also carries a risk of excessive bleeding. Tennessee researchers reported on a new approach that worked better in a mouse study.

Iron buildup in the brain may be related to the development of neurodegenerative diseases. Researchers have found the mechanism leading to this iron accumulation, at least in mice.

Reducing the risk that stroke patients face of falling can be a matter of chosing proper oral anticoagulants.Researchers said edoxaban is less risky than warfarin.

The scoring system known as CHA2DS2-VASc is commonly used as a clinical guideline for assessing ischemic stroke risk in patients with atrial fibrillation (AF). A research team from Santiago, Chile found it can also predict vascular dysfunction and cardiovascular events in high-risk patients who do not have AF.

Independent of cardiac risk factors, including chronological age and blood pressure preserved telomere length "represents healthy cellular aging," Dhananjay Vaidya and colleagues at Johns Hopkins University reported in an abstract.

A New York City research team believes that clinical SLE disease is associated with microbiome imbalances, specifically with decreases in the diversity and blooms of specific operational taxonomic units in the intestine.

Patients who had bariatric surgery and lost weight were likely to also see improvement in symptoms of psoriasis and psoriatic arthritis, NYU Langone researchers report.

Estimates on the prevalence of systemic lupus erythematosus (SLE) in the US vary widely. To remedy that situation, the US Centers for Disease Control and Prevention supported four health departments and the Indian Health Service in efforts to get better data.

A Swiss team found that tocilizumab (Actemra/Genentech) was effective in treating newly diagnosed or relapsed patients with giant cell arteritis.

A UK team reporting at the American College of Rheumatology Annual Meeting in San Francisco, CA said it found that adalimumab (Humira/AbbVie) helped patients who had active JIA-associated uveitis

Study results show treatment with tofacitinib imrpveos symptoms in patients with ankylosing spondylitis.

A multinational group known as GRAPPA has compiled a new set of treatment recommendations for psoriasis and psoriatic arthritis.

Giant cell arteritis is effectively treated with glucocorticoids, but they have side effects and patients tend to relapse. Researchers evaluated abatacept combined with prednisone and saw fewer relapses.

A research team in the UK looked at how well rituximab (Rituxan/Genentech) improved the Sjogren's Syndrome symptoms of fatigue and dry mouth.

Although gout has historically been thought to be a rare in patients with SLE, a recent case series suggests that the incidence of gout in SLE may be greater than previously thought, University of Michigan researchers report.

Reporting at the American College of Rheumatology Annual Meeting in San Francisco, a team from Japan reported on a novel humanized monoclonal antibody called E6011, one that targets fractalkine-CX3CR1, with a research goal of stopping the chemokine's accumulation in inflamed tissues in rheumatoid arthritis.

The FDA approved a new combination tablet that provides once-a-day dosing for patients with HIV-1 infection.

Asthma treatment approved as "add-on" for patients with severe asthma.

Short winter days can trigger seasonal affective disorder. Vermont researchers said they got longer lasting therapeutic results with cognitive behavioral therapy than with light therapy--apparently because people tire of using the lights.

Childhood pertussis carries an increased risk of developing epilepsy, Danish researchers report.

There are many varieties of type 2 diabetes, a new genotype analysis shows. Tracking these genotype variations in common diseases is possible using data from electronic medical records (EMRs), according to researchers at the Icahn School of Medicine at Mount Sinai in New York City.

Don't eat in the barn is the takeaway from an E.coli outbreak that hospitalized children in Washington State. Sixty cases were identified after a school field trip to a dairy farm where food was served in a cattle barn.

Sudoku puzzles may serve as a "brain workout" but in a case reported in Germany, the exercise proved too strenuous. Solving the puzzles gave a 25-year-old man seizures.