Giuliana Grossi

Coverage restrictions on biosimilars were observed in highly prevalent diseases but were less likely in biosimilars that generate an annual list price savings of more than $15,000 per patient.

Compared with nasal masks, oronasal masks are associated with a more collapsible upper airway, requiring higher therapeutic CPAP levels, according to the study.

Hyporesponse to erythropoiesis-stimulating agents was associated with increased rates of red blood cell transfusions and poorer outcomes in patients with chronic kidney disease, highlighting the need for alternative anemia treatments.

The longitudinal study finds prevalent obstructive sleep apnea, insomnia, and sleepiness could differentially mediate or moderate the effect of multiple sclerosis on cognition.

Insomnia shows associations with higher rates of outpatient visits, hospitalizations, and fills for medications, longer hospital length of stay, and higher hospitalization costs.

Results show ISR is a promising behavioral treatment for insomnia, which can reduce sleep latency, increase total sleep time as well as sleep efficiency, and may serve as an alternative to traditional treatments.

The cross-sectional analysis found a significant association between greater insomnia severity and worsened quality of life, decreased productivity, and increased healthcare resource utilization.

A new study has found individuals with depression and insomnia show significantly less activity in the prefrontal cortex during verbal fluency tests, suggesting that sleep quality is an important indicator in fNIRS screening.

New data quantify the exposure to wildfire particulate matter among schoolchildren in California, finding that interventions in a small number of schools may reduce the overall burden of wildfire PM2.5 exposure.

Results reveal changes in sleep problems across adolescence are associated with internalizing and externalizing symptoms, highlighting the need to address this early.

New data demonstrate suvorexant and lemborexant were equally effective in improving sleep status, but lemborexant may cause side effects less frequently.

The petition with the US DEA is aiming to remove dual orexin receptor antagonist medications from the Controlled Substances Act due to negligible potential for abuse.

The monthly prophylactic injection reduces bleeds by interfering with the production of specific proteins for both types of hemophilia with or without inhibitors.

Investigators found girls with depression and anxiety responded especially well to melatonin treatment, suggesting the potential of sleep interventions in reducing the risk of self-harm.

Digital Cognitive Behavior Therapy for Insomnia (CBT-I) is equally effective in treating insomnia in individuals with or without co-occurring chronic fatigue, according to a recent study.

New data demonstrate a concerning link between particulate matter ≤2.5 μm exposure and the risk of prolonged symptoms of COVID-19 in young adults.

Is the prevalence of cardiac involvement in patients with sarcoidosis underestimated? Advanced imaging could lead to illuminating discoveries.

Future research could explore the factors contributing to this disparity and identify effective interventions to reduce tobacco use in this population.

Investigators developed and validated a tool for daily assessment of asthma control that can be utilized in clinical trials as an endpoint.

The ANTICOVID clinical trial finds high-dose prophylactic anticoagulation reduces risk of de novo thrombosis in COVID-19 pneumonia.

Phase 2/3 data show significant improvement in lymphoproliferation as measured by the reduction in lymph node size and increase in naïve B cells in patients with activated phosphoinositide 3-kinase delta syndrome.

The results of a comprehensive meta-analysis indicate a high prevalence of comorbidities among asthma patients, emphasizing the importance of effective treatment strategies.

Data from a meta-analysis show late gadolinium enhancement (LGE) on cardiac MRI scans and elevated fluorodeoxyglucose (FDG) uptake on PET scans are both strong predictors of major adverse cardiac events for cardiac sarcoidosis.

Data also show significant improvements in quality of life and respiratory symptoms in patients with evidence of type 2 inflammation who were treated with dupilumab.

Proposed biosimilar AVT04 shows comparable efficacy to ustekinumab.

“These findings are exciting for us, and our overarching goal is to develop microbial biotherapeutics to treat food allergies," Mustafa Özçam says in an interview with HCPLive.

Where access to healthcare is limited, the impact of diagnostic bias based on skin tone can result in a greater burden of disease and even more deaths, especially for Black individuals.

As little as 39 minutes less sleep per night for 1 week can have an impact on the quality of life of children.

New data demonstrates that onasemnogene abeparvovec is an effective treatment option for symptomatic and presymptomatic patients with spinal muscular atrophy (SMA).

“We have now seen consistently across the program the potential to quite meaningfully reduce Phe levels in patients with PKU," lead investigator Dr. Jerry Vockley says in a statement.