Despite rampant opioid misuse, abuse, and diversion self-reported by chronic pain patients in a study presented at the American Pain Society 33rd Annual Scientific Meeting, primary care providers tended to downgrade the patients' risk for engaging in those drug-related aberrant behaviors, indicating a gap between physicians' objective risk assessment for opioid abuse and the actual extent of the problem.
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Perceptions of Pain Education at Top-rated Medical Schools Conflict with Reality
May 3rd 2014Medical and nursing schools that reported extensively incorporating the topic of pain care into prelicensure curricula do not offer more robust pain management education programs than those indicating minimal or moderate pain course integration.
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Analgesic Requirements for Pain Related to Acute Pancreatitis
May 2nd 2014Patients who are hospitalized for pain related to acute pancreatitis pose unique challenges for achieving adequate analgesia, which is particularly true for those admitted with preexisting chronic pain and prior opioid use.
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Opioid-induced Constipation Is More Than a Tolerability Issue
May 2nd 2014Though constipation as a side effect of opioid therapy is generally considered a tolerability issue that can be treated with over-the-counter laxatives, opioid-induced constipation may still lead to serious gastrointestinal complications.
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Restoring the Path to Multidisciplinary Chronic Pain Management
May 2nd 2014Although the concept of delivering chronic pain care through multidisciplinary clinics is less than half a century old, John Loeser, MD, believes the model has already surpassed its peak in the United States, mainly due to financial reasons.
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Cancer-related Pain Experience Differs by Race, Ethnicity
May 1st 2014With the co-occurrence of chronic pain and cancer amassing from improved cancer survival rates, it is increasingly important for healthcare professionals to understand how the conditions interrelate and influence patients' quality of life.
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Vitamin D Supplementation May Reduce Pain, Improve Sleep in Knee Osteoarthritis Patients
May 1st 2014Expanding upon previous investigations of the associations among low vitamin D levels, chronic pain, and poor sleep within the general and non-pain populations, a research poster presented at the American Pain Society 33rd Annual Scientific Meeting suggests correcting inadequate vitamin D levels in middle-aged to older patients with knee osteoarthritis may reduce their clinical pain and improve sleep quality.
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Long-term Botox Treatment Sustains Prevention of Chronic Migraine Headaches
May 1st 2014Although the benefit of Botox (onabotulinumtoxinA) for preventing headaches in adults with chronic migraine has been extensively established in clinical trials, limited data exists on the injections' effectiveness for the indication beyond 5 treatment cycles.
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Trial of Novel Heart Failure Drug Terminated Early Based on ‘Compelling Efficacy'
April 2nd 2014Citing interim results that met parameters for efficacy in reducing cardiovascular mortality, an independent group of experts has put an early stop to a late-stage study on Novartis's novel oral medication for chronic heart failure.
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Cancer Survival Complicates Chronic Pain Management
March 10th 2014As long-term cancer survival rates continue to surge, an increasing percentage of patients with cancer-related pain are progressing to the chronic pain arena, which necessitates more contemporary treatment approaches to cancer pain management.
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Pain Experts Poke Holes in Published Clinical Treatment Guidelines
March 10th 2014Although they have all participated in the development of treatment guidelines for a variety of pain conditions, 3 comprehensive pain experts openly acknowledged and discussed the practical limitations of published evidence-based recommendations during the closing session of the American Academy of Pain Medicine 2014 Annual Meeting.
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With Behavioral Support in Place, Opioid Dose Reduction Does Not Exacerbate Pain or Function
March 9th 2014Reducing high-dose opioid therapy does not worsen pain severity, functional ability, or aberrant drug-related behaviors in chronic pain patients when concurrent biopsychosocial services are offered.
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Predicting Positive and Negative Symptom Exaggeration in Chronic Pain Patients
March 9th 2014Sometimes, chronic pain patients intentionally magnify or downplay their physical and mental symptoms during office visits. Despite that fact, little attention in the clinical setting is paid to underlying motives for positively or negatively biased self-reports.
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Mindfulness-based Pain Care Provides Opioid Taper Support
March 8th 2014Even if a chronic pain patient had been taking opioid medications exactly as prescribed, it would still be possible for the patient to experience negative cognitive and emotional responses to dose tapering that could amplify sensory pain and lead to opioid addiction.
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Researchers Emphasize Routine Urine Drug Testing to Ensure Opioid Compliance, Enhance Pain Care
March 8th 2014In light of the fact that many physicians continue to rely on observational analysis and patient self-reporting to monitor opioid addiction or misuse, results from a scientific poster reinforced the benefits of routine urine drug testing in improving compliance with prescribed opioid medications and ultimately enhancing pain care.
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Guidelines for Knee Osteoarthritis Management Miss Treatment Targets
March 8th 2014Though different sets of treatment recommendations for knee osteoarthritis send conflicting messages to practicing physicians, James W. Atchison, DO, pointed out that the guidelines focus solely on the knee, while pain management specialists focus on the whole person.
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Opioid-Induced Constipation Is Not Adequately Reported by Chronic Non-Cancer Pain Patients
March 7th 2014Preliminary research data revealed a significantly higher incidence of opioid-induced constipation among patients taking opioid analgesics for chronic non-cancer pain than self-reported constipation complaints suggest.
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Grouping Fibromyalgia Patients by Symptom Incidence, Severity May Improve Treatment Outcomes
March 7th 2014Although fibromyalgia lacks an effective standardized treatment, one part of the problem is the condition's diverse constellation of symptoms that include chronic widespread pain, fatigue, and even depression.
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Brintellix Tackles Cognitive Dysfunction Related to Major Depression
December 13th 2013In addition to treating episodes of major depression, Brintellix (vortioxentine) has demonstrated superiority to placebo on measures of cognitive function in adult patients with major depressive disorder (MDD).
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Meniscus Extrusion Predicts Radiographic Osteoarthritis Change Better Than Cartilage Volume Loss
October 30th 2013Although change in knee joint space narrowing depicted on radiographs is considered the gold standard for monitoring osteoarthritis progression and knee cartilage volume loss, the method doesn't account for extrusion of the medial meniscus, which new research suggests can better predict radiographic osteoarthritis change over time.
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Biologics Beat Triple DMARDs Therapy on Cost, But No Winner in Debate on Efficacy, Safety in RA
October 30th 2013During their "Great Debate" keynote session of the American College of Rheumatology (ACR) 2013 Annual Meeting in San Diego, CA, two leading rheumatologists took direct aim at each other's significant clinical trial data to provide rationale for choosing biologics over triple therapy - or vice versa - as the treatment of choice for rheumatoid arthritis (RA).
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Tocilizumab Treatment Associated with Cardiovascular Improvements in RA Patients
October 29th 2013Though rheumatoid arthritis (RA) patients have a significantly higher risk of developing cardiovascular disease (CVD) compared to the general population, results from a pair of studies show that the biologic disease modifier Actemra (tocilizumab) may actually improve the cardiovascular (CV) profiles of RA patients.
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5-Year Efficacy Data Shows Golimumab Yields Long-Term RA Improvements
October 29th 2013As a follow-up to the initial establishment of Simponi (golimumab)'s safety and efficacy in rheumatoid arthritis (RA), researchers presented final 5-year data evaluating the tumor necrosis factor (TNF) blocker's effects in RA patients taking methotrexate and those naïve to the biologic agent.
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Studies Say Vitamin D Deficiency Doesn't Increase Odds of RA, But May Worsen OA Symptoms
October 28th 2013Though previous reports have described a link between vitamin D deficiency and an increased risk of rheumatoid arthritis (RA) development, a trio of studies has now offered clinical support to the contrary belief.
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