Authors



Lexa W. Lee

Latest:

Updates in Surgery: Percutaneous Coronary Intervention, Perioperative Biomarkers, and Troponin

During a follow-on session at the 2013 Southern Hospital Medicine Conference, Steven Cohn, MD, discussed the effect of PCI on subsequent non-cardiac surgery outcomes, monitoring specific hormone levels as indicators of cardiovascular risk, and other hot topics in perioperative medicine.


Anita Deswal, MD, MPH

Latest:

Outcomes in women vs men with heart failure and preserved ejection fraction

The epidemiologic finding that women with heart failure have better overall survival than men may be because of the higher prevalence of diastolic heart failure or heart failure with preserved ejection fraction (HF-PEF) among women.




Antoni Ribas, MD

Latest:

Melanoma: Improving Clinical Outcomes Through Advances in Immunotherapeutics and Targeted Therapy

Metastatic melanoma has limited treatment options, but advances in the understanding of the oncogenic mutations that drive this cancer and how the immune system can be better modulated to fight melanoma provide a new generation of active approaches for patients.



associate professor of medicine, Division of Cardiology, Johns Hopkins Hospital, Baltimore, Maryland, an

Latest:

Thoracic and abdominal aorticatherosclerosis

It was not until Virchow identified the cellular contributions to thrombosis that physicians began to visualize arteries as dynamic tissues.



Todd Kislak

Latest:

A Tour of Hospital Medicine in the Blogosphere

With the ranks of hospitalists already over 20,000 strong and growing every day, hospital medicine is the fastest-growing medical specialty in the history of American healthcare


epidemiology, Division of Cardiology, The Johns Hopkins University, Baltimore, Maryland.

Latest:

Uncovering masked hypertension: Is the blood pressure really normal?

A number of studies have documented the incremental predictive ability of 24 hour ambulatory blood pressure (BP) monitoring over traditional office or casual BP monitoring for predicting adverse cardiovascular events.


Brian Bigger, Ph.D.

Latest:

A Sense of Urgency in Sanfilippo Therapy Development

With no real standard-of-care for Sanfilippo syndrome patients, Brian Bigger, Ph.D., discusses the sense of urgency he and his colleagues feel while researching.



Stefan H. Ostermayer, MD

Latest:

Transcatheter occlusion of the left atrial appendage to prevent stroke in atrial fibrillation

We conducted 2 feasibility studies to assess the performance and safety of the percutaneous left atrial appendage (LAA) transcatheter occlusion system for the prevention of stroke in high-risk patients with nonrheumatic atrial fibrillation. Results showed that percutaneous LAA occlusion can be performed using the device at acceptable risk. This procedure may be particularly useful for patients at increased risk of ischemic stroke with a contraindication to anticoagulation therapy.


Martin Dunkelgrun, MD1

Latest:

Are statins cardioprotective in patients undergoing major vascular surgery?

We evaluated the cardioprotective effects of intensive statin therapy before major vascular surgery in a prospective study of 359 subjects. After multivariate analysis, lower low-density lipoprotein (LDL) cholesterol was associated with decreased myocardial ischemia, troponin T release, and 30-day and late cardiac events. Furthermore, higher doses of statins were associated with better cardiac outcome, even after adjusting for LDL cholesterol.



Frank J. Domino, MD

Latest:

What Role Do Muscle Building Supplements Play in Testicular Cancer

With muscle supplements being a popular addition to exercise regiments their potential health risks also remain a concern.



Benjamin Bier, MS IV

Latest:

Taking Steps to Reduce Cardiovascular Outcomes in a High-risk Population

Family physicians should place as great an emphasis on walking as they do on monitoring medication and laboratory data, and strongly recommend increased ambulatory activity to their patients.


Robert J. Goldberg, PhD1,2

Latest:

Survival after heart failure

We conducted a multi-hospital population-based study of 2445 residents of a large New England metropolitan area hospitalized with acute heart failure and found that the long-term prognosis for these patients remains poor. More than one third of patients died in the first year after hospital discharge,and nearly 4 of 5 patients died over the 5-year follow-up period. Several demographic and clinical factors were associated with an adverse prognosis. It is important to know the factors that negatively affect long-term survival after hospital discharge for decompensated heart failure so that treatment can be directed toward specific high-risk groups.


W. Gregory Hundley, MD

Latest:

Contemporary cardiac imaging in hypertrophic obstructive cardiomyopathy

Features of hypertrophic obstructive cardiomyopathy (HOCM) include obstruction at the left ventricular outflow tract (caused by a markedly thickened proximal interventricular septum) and systolic anterior motion of the mitral valve. The case discussed here illustrates several classic features of this disease including clinical presentation, diagnostic workup, and noninvasive and invasive management.


Martin Osranek, MD, MSc

Latest:

Atrial fibrillation after cardiac surgery

We assessed preoperative cardiac physiology using echocardiography in patients undergoing cardiac surgery to identify predictors of postoperative atrial fibrillation. Subjects with enlarged left atrial volume had a 5-fold greater risk of postoperative atrial fibrillation, independent of age and other risk factors, than those without enlarged left atrial volume. Left atrial volume appears to be a powerful tool to stratify patients according to risk before surgery and to effectively target preventive therapy.







Susan Weisman

Latest:

A Caregiver's Perspective: Light Chain (AL) Amyloidosis Treatment

Susan Weisman, a light chain (AL) amyloidosis caregiver for her husband since 2009, touches on a few of her husband's treatments in an approximate timeline.


Marica Frellick

Latest:

AHA 2010: Prescription Omega-3 Useless in Atrial Fibrillation

Researchers find no benefit from prescription omega-3 in patients with paroxysmal atrial fibrillation who do not have significant heart disease.


Quynh-Van Tran, PharmD

Latest:

Effect of Inadequate Response to Treatment in Patients With Depression

This study sought to assess the effects of inadequate response to antidepressant treatment on healthcare resource utilization and on work productivity in patients diagnosed as having major depressive disorder.

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