Cardiology

The supplemental BLA seeks FDA approval for alirocumab (Praulent) as a treatment to reduce overall risk of major adverse cardiovascular events.

Interestingly, increased distress led to a higher risk of stroke for women, while distressed men had a higher risk of heart attack.

Mice treated with ACE inhibitors demonstrated preservation of cognitive function, preserved dendritic complexity, a normal spine number, and significantly less microglial activation.

The risk of acute coronary syndrome recurring after hospitalization was not found to be increased in individuals infected with HIV.

Though previous research showed telemonitoring and pharmacist consultation helped patients manage blood pressure for about one year, researchers have been unsure whether it would provide sustained, long-term benefits in at-risk patients.

Deaths due to drug overdoses and suicides have contributed to decreasing US life expectancy, but other factors indicate that there is a deeper root cause driving these trends.

The CDC reports that, while tobacco use has decreased, cardiovascular disease risk factors and rates of cardiovascular management are still in need of improvement.

Preliminary findings from WTC Health Program are the first to make the connection among workers at "Ground Zero."

Ticagrelor 60 mg and 90 mg tablets have been indicated for lowering the risk of heart attack, or death from heart attack or stroke in patients with acute coronary syndrome.

Study of abrupt versus gradual reduction of nicotine informs FDA-proposed rule on reducing cigarette nicotine to "minimally addictive" levels.

The heart rhythm specialist with the UVA Advanced Imaging group discussed his team's early successes with Medtronic's heart ablation vest.

In a phase 2/3 trial, the Bayer Pharmaceuticals therapy demonstrated protection from bleeding and patient safety for up to a median of 1.9 years.

Is there a link between vitamin D deficiency and mortality in patients with heart failure? A new study may have the answer. 

Stem cell research from the University of Michigan reveals dangerous cardiac effects of a gene mutation in patients with Dravet syndrome.

How the conflicting results of the ASCEND trial are actually much more determinant than they appear, and critical in the scope of treating comorbidities in patients with diabetes.

In a 15,000-plus patient analysis that spanned more than 7 years, aspirin reduced vascular risks in patients—but also increased their rate of major bleeding events.

Patients administered the FDA-approved therapy reported tripled rates of weight-loss, along with noninferiority for risk of major cardiovascular events, over 1 year and an extension period.

The update reported significant improvements in future cardiovascular risks in patients at risk for chronic angina initially referred for CTA plus standard care, versus those only referred to standard care.

In an analysis of 118 clinical trials since 2001, investigators found females and minorities comprised just 27% and 22% of the total patient population, respectively.

Compared to those with LDL cholesterol levels 160 mg/dL had a 70-90% increased risk.

A new study suggests that subclinical RV dysfunction may cause exercise-induced dyspnea in compensated subjects with PAH.

Treating patients with methamphetamine-associated PAH presents unique challenges including the pros and cons of placing venous access ports.

The celebrity chef-turned-producer wants to champion healthcare access, both on the screen and in person. Where does he start?

This combination of telmisartan, amlodipine, and chlorthalidone reduced blood pressure to target levels in 69.5% of patients at 6 months, compared to 55.3% of patients receiving usual care.

Galafold differs from common enzyme replacement therapy in that it increases the activity of the body’s deficient enzyme.

For patients with acute coronary syndrome and depression, taking escitalopram to treat depression resulted in significantly fewer major cardiac events compared to patients given placebo.

Women and men are more likely to survive when treated by female doctors compared to male doctors, but the difference in heart attack survival is greater for women.

Researchers were able to rule out myocardial infarction in 30% of patients immediately, and another 25% of patients at 1 hour. By 3 hours, the assay had successfully ruled out MI in 83.8% of patients, versus the 80.4% ruled out under the conventional assay.

Research suggests that elevated glycemia, low blood pressure, and low BMI may be identifying markers for dementia risk and possible targets for management or prevention.

The optimal duration of dual antiplatelet therapy remains unclear, despite being proven efficacious for roughly 2 decades.