The HCPLive Cardiology condition center page is a comprehensive resource for clinical news and insights on cardiovascular and cardiometabolic diseases. This page consists of interviews, articles, podcasts, and videos on the research, treatment and development of therapies for heart disease and cardiovascular events, as well as associated diabetes, renal failure, and more...
September 19th 2024
EDG-7500 was well-tolerated in healthy patients in Phase 1 while achieving gradient relief without LVEF reductions in the Phase 2 CIRRUS-HCM trial.
September 12th 2024
September 10th 2024
Elevating Care for PAH: Applying Recommended Management Approaches to Maximize Outcomes
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‘REEL’ Time Patient Counseling™: Navigating the Complex Journey of Diagnosing and Managing Fabry Disease
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Expert Illustrations & Commentaries™: Envisioning Novel Therapeutic Approaches to Managing ANCA-associated Vasculitis
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Clot-prevention Therapies: No Clear Answer
Dual antiplatelet blood-thinning therapy (DAPT) immediately after stenting with a drug-eluting device has been shown to prevent major cardiac events and stent thrombosis in most patients. Current American College of Cardiology and American Heart Association guidelines recommend 12 months of therapy post-stenting. But out of concern over potential risks of continuing the drugs longer, or even indefinitely, the US Food and Drug Administration (FDA) asked device manufacturers to study the longer-term consequences of the therapy.
Pharmacogenetics Helps Fine-Tune Warfarin Dosing in Kidney Disease
November 16th 2014Though warfarin has long been the mainstay of anticoagulation in atrial fibrillation (AF), dosing is complicated by a host of factors, and the drug has a famously narrow therapeutic range. One way to fine-tune warfarin therapy is to account for genetic variation.
Consider Individual Risks, Benefits for Anticoagulation in Chronic Kidney Disease
November 15th 2014Anticoagulation is recommended for members of the general population with atrial fibrillation, but its significant risks must be weighed carefully in the medically fragile chronic kidney disease population.
Atrial Fibrillation Associated with Accelerated Renal Disease; Ablation May Help
November 15th 2014Treatment of atrial fibrillation (AF) in patients with CKD may help prevent disease progression. Ablation has been shown produce marked improvement in kidney function as measured by eGFR. A prospective study of individuals undergoing catheter ablation for AF showed that most patients remained AF-free, and that eGFR improved significantly for those with persistent or longstanding persistent AF.
Cinacalcet May Reduce Cardiovascular Risk for Older Kidney Disease Patients: EVOLVE Re-Analysis
November 14th 2014Secondary hyperparathyroidism can occur in CKD when the kidney loses its ability to produce active metabolites of vitamin D, and reduces phosphorus excretion. Cinacalcet seeks to interrupt the progression to severe unremitting hyperparathyroidism by mimicking calcium to the calcium-sensing receptors that control parathyroid hormone levels.
Understanding ANCA-Associated Vasculitis
Affecting just one in every 100,000 people, ANCA-associated vasculitis is not one of the more common conditions nephrologists will encounter. However, without proper treatment it can have serious adverse effects on a patient's life.
Cardiac Regeneration Provides Hope for Future Heart Patients
Heart failure and other cardiac events can leave lasting effects on the lives of patients. Scientists are working on ways to help make the recovery process easier and smoother by generating cells that can help the healing process.
Most Stable Heart Patients Do Not Need Beta-Blockers
Taking beta blockers-a common drug regimen for patients with clinically stable coronary heart disease (SCHD)-likely does not have a benefit or outweigh these drugs' risk for most patients, a University of Florida team report.
Age-related Diseases don't Occur Earlier in HIV-infected Patients
November 13th 2014Despite previous research suggesting HIV patients have an increased likelihood of suffering from a heart attack, kidney failure, or cancer, Johns Hopkins Bloomberg School of Public Health investigators showed the age they encounter these conditions were similar to their uninfected counterparts.
Diabetes & Low T: Treat Testosterone Deficiency?
November 12th 2014Low testosterone is a common condition among men with diabetes-diabetic men are approximately twice as likely as others to develop low testosterone and hypogonadism. Because its symptoms mimic other conditions, patients often fail to report concerns and clinicians may fail to diagnose "Low T."
It is well known that patients who get primary percutaneous coronary intervention (PCI) after an ST segment elevation myocardial infarction usually survive. But a new study from Denmark looked at a large population of such patients over several years to track just how many deaths there were each year and from what cause.
Associations Between Atrial Fibrillation and Silent Cerebral Infarctions
A meta-analysis of many older studies may explain the recent observation that patients with atrial fibrillation (AF) frequently suffered cognitive impairment without suffering from any signs of stroke.
Study: Moderate Drinking's Not Heart-Protective for Most
Moderate alcohol consumption can protect against coronary heart disease. But according to a study of 618 Swedes with coronary artery disease, that is true only for those who have a particular genetic makeup, a mere 15% of the general population.
Traditional Dieting, Alternate Day Fasting Similar For Weight Loss in Head-to-Head Trial
November 9th 2014A small but rigorous 6-month randomized, controlled parallel arm trial comparing alternate day fasting and daily calorie restriction showed that each approach can result in significant weight loss for individuals who are overweight or have obesity, with similar adherence between the two methods of dieting.
Less Medication, Better Glycemic Control Seen in Low Saturated Fat Diet for Type 2 Diabetes
November 9th 2014For individuals with type 2 diabetes mellitus, a low carbohydrate, low saturated fat diet in combination with exercise resulted in superior glycemic control with less medication use than did a higher carbohydrate diet
Algorithms Not Sole Factor in Prescribing for Obese Patients
November 6th 2014There is currently no algorithm to guide clinicians in deciding which medication to choose to help promote weight loss in individuals with obesity. Rather, clinicians must take stock of a variety of factors when making treatment decisions for a particular patient.
New Device Beats Placebo, Produces Durable Results in Moderately Obese Patients
November 6th 2014An intragastric dual-balloon device was well tolerated and proved effective for patients with moderate levels of obesity, owing in part to its ability to conform to stomach anatomy, according to Jaime Ponce, MD, Medical Director for the Bariatric Surgery program at Hamilton Medical Center, in Dalton, Georgia.