Chronic Pain

Study results suggest that lidocaine injection might be better than ischemic compression in treating chronic pelvic pain in women.

Total hip arthroplasty (THA) reduces use of analgesics, hypnotics and anxiolytics to extend the positive effects of surgery according to a Norwegian study of pre- and post-operative prescription trends in the Nov. 14 issue of Pain.

A recent review provides a sobering picture of the missing clinical links in research regarding current pharmacological treatment for chronic postoperative pain.

An estimated 20% to 35% of children worldwide suffer from chronic pain, according to the American Pain Society, but treating the condition has added challenges for the younger population.

New research further supports the understanding that patients with hemophilia suffer from pain and mobility issues, and it went on to uncover which joints are most greatly affected by the condition.

Pain crises are common in those with sickle cell disease, but now new research may have identified biomarkers for patients whose pain becomes chronic.

If copper clothing is on your list of options to treat chronic pain, you might want to rethink that one.

The world's first and only non-rechargeable, upgradeable spinal cord stimulation system could change the way that physicians treat chronic pain.

Patients with rheumatoid arthritis who received sarilumab plus a DMARD who did not respond to anti-TNF medications showed statistically significant and clinically meaningful changes from baseline in fatigue, morning stiffness, pain, productivity, and participation at week 24.

A recent study suggests that pain is inadequately treated in emergency departments, for a variety of reasons.

The US Food and Drug Administration (FDA) has approved Belbuca (buprenorphine) buccal film (developed by Endo Pharmaceuticals and BioDelivery Sciences) for treating chronic pain in patients for whom existing alternatives don't work.

Canadian researchers suggest that quality-controlled herbal cannabis, if used by cannabis-experienced patients as part of a monitored treatment program over one year, appears to be reasonably safe for the treatment of chronic pain.

On the battlefield soldiers can suffer any number of injuries that can lead to a lifetime of painful injuries. How doctors approach that care can affect the quality of life their patients enjoy long after their time in the service is done.

Like every year, PAINWeek, which kicks off this week in Las Vegas, will include dozens of presentations on abuse and diversion. It is a topic that is always front and center for pain management practitioners, and one for which there are no easy answers.

The source of neuropathic pain is a biological process called endoplasmic reticulum (ER) stress, according to findings published in the journal Proceedings of the National Academy of Sciences (PNAS).

Lidocaine metabolite N-ethylglycine (EG) relieves hyperalgesia and allodynia in animal models for chronic pain, suggests a study in Pain. The finding is an indicator that use of Glycine transporter 1 substrates might constitute a new drug target for the modulation of glycinergic inhibition in pain signaling.

Canada-based researchers examined the effectiveness of opioids for the long-term management of chronic neuropathic pain and found less than encouraging results, according to a study in The Journal of Pain.

A recent study in the Journal of Pain Research found that placing an electrical stimulation device properly doesn't necessarily increase the pain threshold for health patients subjected to transcutaneous electrical nerve stimulation (TENS). The finding is important because TENS is among many nonpharmacological interventions for pain around which clinical opinion on effectiveness is split.

Stress resulting from frequent migraine headaches may contribute to the development of medical and psychological comorbidities that can result in an ugly cycle of more migraines, according to a study in the Journal of Pain Research.

A Japanese study suggests that parental bonding style during childhood is associated with the prevalence of chronic pain in adults in the general population and that the association is more robust for paternal bonding than for maternal bonding.

Three recent studies – in three very different publications – add to a growing cache of evidence showing that music can have significant benefits for patients with pain.

While a common method used to treat low back pain may provide immediate relief, its effects do not extend for a substantial period of time, a new analysis has found.

Mobility is great. Hypermobility? Less great. In the joints, hypermobility leads to musculoskeletal pain – and often times, lots of it. A recent review in the Journal of Pain Research outlined several of the challenges in treating generalized joint hypermobility (GJH) and found many difficult questions and few easy answers.

Not only have researchers from Mount Sinai Hospital discovered that common antidepressants can help treat neuropathy, but they also identified the gene associated with pain and depression.

Leflunomide, marketed under the brand name Arava, is a safe and effective treatment for early rheumatoid arthritis, according to a study in International Journal of Rheumatic Diseases.

Patients with fibromyalgia typically experience widespread chronic pain and a new study adds to the evidence that emotional impact is prominent as well.

Female mice models felt pain differently than their male counterparts, according to a study published in Nature Neuroscience.

Researchers from Kyoto University's Institute for Integrated Cell-Material Sciences (iCeMS) may have found a way to control cell functions in order to alleviate intractable pain.

Data concerning general outcomes and indicating performance of general pain clinics remain sparse, according to a study in the Journal of Pain and Research. The United Kingdom study suggests that this lack of standardized measurements negatively impacts the ability to judge the overall effectiveness of pain clinics, both in the UK and in other parts of the world.

A recent study in The Journal of Headache and Pain sheds some additional light on the chronobiological experience of patients with cluster headache (CH). However, it still leaves lingering mysteries around the pattern of pain CH that patients typically experience, the triggers of those headaches, and the mechanisms and interactions that drive headache frequency and severity.