Dermatology

Arthritis drugs, such as tofactitinib and other Janus kinase inhibitors, may be effective treatments for vitiligo.

The healthcare technology company Philips has launched BlueControl 2.0, a device created to treat patients afflicted with psoriasis.

Antibiotic resistance, a grave concern spanning across all medical specialties, can be especially disconcerting in dermatology.

The Food and Drug Administration expanded the approved use of ipilimumab so that it will include a new indication as adjuvant therapy for patients with stage III melanoma. The approval is big news, because it's the first new FDA-approved adjuvant option for late-stage melanoma in two decades.

An analysis of 35 years of cohort data provides fresh information about the biggest risk factors for cardiovascular disease in patients with psoriatic arthritis.

Everyone is constantly awaiting "the next best thing." This concept also holds true in the arena of skin cancer treatment.

Study results indicate a novel combination of the BRAF inhibitor vemurafenib plus cediranib, an investigational drug that targets the mitogen-activated protein kinase enzymes MEK1 and MEK2, may be effective in treating malignant melanoma.

Research suggests support groups help teenagers with diagnosed allergies adhere consistently to guidelines that protect them against anaphylaxis and other reactions.

How expensive? Study results show that families with children who are allergic to staple food items pay out thousands of extra dollars each year in direct and indirect costs.

Although asthma increases the risk of anaphylaxis in children with milk allergies and reduces the chance that immunotherapy will prove fully successful, study results show that the majority of patients who undergo immunotherapy for a milk allergy can achieve a protective dose.

Earlier this year, a skin patch designed to reduce the risk of anaphylaxis and other severe reactions to peanuts became the first allergy treatment ever granted a Breakthrough Therapy Designation by the FDA.

The US Food and Drug Administration has approved the first-in-class oncolytic immunotherapy talimogene laherparepvec (T-VEC; lmlygic) to treat unresectable cutaneous, subcutaneous, and nodal lesions in patients with melanoma recurrent after initial surgery.

A meta-study of randomized controlled trials indicates that older TNF-inhibitors such as etanercept or infliximab treat psoriatic arthritis more effectively than newer TNF-inhibitors.

There really is an app for everything.

A retrospective review suggests that patients who have cervicofacial rhytidectomy (face lift) after radiotherapy are likely to have increased complication rates over patients who have not had radiotherapy.

A topical foam product combining calcipotriene and betamethasone dipropionate has been approved for the treatment of plaque psoriasis in adults age 18 and older.

Studies show that laser- and light-based therapies can be effective as adjunct therapy in the treatment of hidradenitis suppurativa. Originally introduced to reduce the size of pores in acne treatment, laser- and light-based therapy is showing potential in other forms of dermatologic treatment.

Secukinumab was more effective than placebo in patients with psoriatic arthritis in a second phase 3 trial, strengthening the case for approval as a treatment for the disease.

New York Giants tight end Daniel Fells remains in a New York hospital in serious condition following the discovery of a severe infection of methicillin-resistant Staphylococcus aureus (MRSA) in his ankle.

Psoriasis patients are susceptible to artery inflammation, increasing their risk for cardiovascular disease.

Researchers reported that treatment with isotretinoin is not only associated with significant clinical improvement in patients with moderate to severe acne, but it also did not cause worsening of depression or suicidal thoughts in any of the patients in the study.

The use of filtered sunlight is both safe and noninferior to conventional phototherapy for the treatment of neonatal hyperbilirubinemia. This is important because severe neonatal hyperbilirubinemia can lead to fatal complications, and because in some cases, existing guidelines for managing neonatal hyperbilirubinemia explicitly discourage the use of sunlight for the treatment.

A German cohort study in Archives of Dermatological Research found that antipsoriatic drugs for treatment of moderate-to-severe psoriasis are generally safe over the long-term.

Phototherapy with ultraviolet A-1 (UVA-1) has been considered a promising treatment option for patients afflicted with alopecia areata.

A recently published article in JAMA Dermatology explored the curious relationship between psoriasis and depression, since psoriasis has been considered a risk factor for depression, and depression a trigger for psoriasis.

Patients with advanced melanoma are living longer when treated with a combination of two targeted therapies, dabrafenib and trametinib than those solely given another drug, vemurafenib.

Pachyonychia congenita (PC), a rare skin disorder, can cause an inordinate amount of neuropathic pain, a study in Clinical and Experimental Dermatology confirms. In the chilling words used by the researchers, "The health states observed in this sample are at a level that the average US citizen would forfeit one-third of their remaining lifespan to avoid."

Treating moderate to severe plaque psoriasis is certainly no picnic for patients' pockets.

Individuals afflicted with psoriasis and psoriatic arthritis are also at higher risk for new-onset migraines.

Patients with cutaneous melanoma metastases responded favorably to combination treatment with intralesional interleukin 2 (IL-2) and topical imiquimod and a retinoid cream.