Endocrinology

Lower testosterone levels may lead men to have less sex with fewer partners, but a new study suggests low levels in both men and women may also increase relationship quality overall.

In an April 2014 study published in Diabetologia, researchers in Germany reviewed phase 3 clinical trial data from all pharmaceutical companies that produced GLP-1 receptor agonists and DPP-4 inhibitors.

New research may explain how and why low in utero testosterone exposure reduces testosterone levels in adult men and increases their consequent risks of obesity, diabetes, and heart disease.

The medical literature reports up to 6% of all deaths in type 1 diabetic patients younger than age 40 are caused by "dead-in-bed" syndrome.

Study results to be presented at the 2014 AAN annual meeting show asymptomatic carotid stenosis may also contribute to impaired memory, cognitive function, and decision making.

A hormone known as IGF-1 may serve as the link between depression and memory loss in older adults.

The nausea and vomiting that accompanies and compromises what should be a happy time for most expecting mothers is poorly understood.

Researchers from the University of North Carolina School of Medicine are contesting a February 2014 Centers for Disease Control and Prevention report that indicated childhood obesity is stabilizing and has dropped 43% among 2- to 5-year-olds.

A new study from the University of North Texas Health Science Center suggests that testosterone replacement therapy may damage brain function in some white men, but not in men of Mexican heritage.

Study shows no correlation between stroke risk among atrial fibrillation patients and the likelihood that they'd receive prescriptions for risk-reducing medication during hospitalization.

In this edition of Clinical Forum, we asked Cardiology Review editorial board members and an invited guest to comment on the controversial new cholesterol guidelines and risk calculator issued by the American Heart Association (AHA) and American College of Cardiology (ACC) in November 2013.

The European Medicines Agency has announced it will evaluate all medications containing testosterone for cardiovascular risk.

The authors of this review believe the efficacy of a drug is important, but it is not the full story.

A review of the relationship between body mass index, metabolic syndrome, and cardiovascular disease and all-cause mortality.

Clinicians have been able to review these guidelines in detail and also take a closer look at how they relate to their patients and practice, the resulting answers are enlightening

Researchers believe the less-invasive nature of transcatheter aortic-valve replacement systems allows patients to mobilize and recover in as little as one week, which contributes to the device's greater survival benefit compared to open-heart surgery.

The US Food and Drug Administration has approved Tanzeum (albiglutide), a once-weekly subcutaneous injection for the treatment of type 2 diabetes in adults.

The Institute of Medicine recently released a list of core social and behavioral health factors it suggests should be captured in all electronic health records to help healthcare providers more effectively influence patient outcomes.

Study results show testosterone therapy reduces total cholesterol, low-density lipoprotein cholesterol, and triglycerides while boosting high-density lipoprotein cholesterol.

A tool for diagnosing and monitoring diabetes has received 510(k) clearance from the US Food and Drug Administration.

The ACC/AHA cholesterol guideline can be a powerful tool for making multifactorial measures of cardiovascular disease risk assessment, particularly in African American populations, but clinicians should be aware of its limitations.

Clinicians should consider a patient's risk of hypoglycemia, the duration of time with the disease, age, comorbidities, vascular complications, and other factors when setting treatment goals.

Several studies have shown good results with Roux-en-Y gastric bypass and laparoscopic gastric banding when combined with lifestyle modifications in severely overweight patients with type 2 diabetes.

Study of farnesoid-x receptor agonist demonstrates protective effects on bacterial translocation from the small intestine in rat model of cholestatic liver disease.

A 57-year-old man presented to clinic with this persistent skin lesion on his thumb. Three months ago, he lanced the lesion, producing some purulence and blood. Since then, it has bled almost daily and has not healed. He was treated with silver nitrate by another clinician after one month, but the lesion persists. His past medical history is significant for diabetes and his family history is significant for 2 cousins with melanoma.

In the field of women's health, the publication of the 2002 Women's Health Initiative (WHI) study was such a defining event that clinicians talk about menopausal hormone therapy "before WHI" and "after WHI."

It is worrisome that "high-impact" data read by most healthcare providers and then further interpreted and distributed by lay news organizations may have funder bias.

Obese women who smoke may not be able to fully perceive creaminess and sweetness, according to a study published in Obesity.

Initiating testosterone therapy in healthy older men substantially increases their risk of myocardial infarction, according to a cohort study published in PLOS One.

Study results show that more than one-third of men with diabetes have low serum testosterone levels, and that risk of low testosterone increases with age.