Endocrinology

The AleCardio trial was halted early due to safety concerns and lack of efficacy. Investigators reported patients with diabetes and acute coronary syndrome experienced elevated risk of heart failure, gastrointestinal hemorrhage, and renal dysfunction with no mitigating cardiovascular benefit.

Study results presented at ACC.14 show treatment with PCSK9 inhibitor evolocumab significantly reduces LDL-cholesterol levels in patients with hypercholesterolemia.

Weight gain in pregnancy is a frequent concern for expectant mothers. Though the exact amount they should gain depends on their pre-pregnancy weight, most American women gain more weight than the Institute of Medicine (IOM) recommends.

Critics allege several major errors in the results of a study that found testosterone therapy is associated with an increased risk for myocardial infarction and stroke.

Hyponatremia is associated with poorer overall survival, time to treatment failure, and disease control in patients with metastatic renal cell cancer, according to a study published in European Urology.

As they age, children who are diagnosed with diabetes shift from care supervised by parents or caregivers to self-care. Ultimately, they must leave their pediatric care providers and find internists and other caregivers whose practices target adults.

As bioimpedance spectroscopy effectively estimates body fluid status, it could replace physical examinations for hyponatremia patients.

Some experts are concerned that efforts to legalize medical marijuana may lead to an increase in the incidence of low testosterone and related conditions such as gynecomastia.

Polycystic ovarian syndrome (PCOS) is the most common problem among women of reproductive age.

This closed-loop insulin delivery system monitors blood glucose continuously and utilizes an algorithm that senses glucose levels and autonomously delivers the required insulin dose. In contrast, conventional insulin pumps contain computer chips that allow patients to program insulin doses for scheduled delivery throughout the day.

Patients with diabetes often develop thiamine deficiency secondary to elevated blood sugar. This deficiency is so common that some experts have referred to it as an epidemic.

Morbidly or severely obese individuals develop migraine disorders significantly more often than patients who carry less weight.

Sodium picosulfate, a commonly prescribed medication for bowel prep prior to colonoscopy, is associated with increased risk of hyponatremia in older adults compared to polyethylene glycol.

Statins can cause diabetes, but other side effects are rare, according to a study published in the European Journal of Preventive Cardiology.

A once-weekly self-injection pen has been approved by the FDA to supplement diet and exercise for type 2 diabetes patients.

Early warning signs of atherosclerosis and other heart diseases may be evident in women who develop gestational diabetes, according to a study published in the Journal of the American Heart Association.

A study in the Journal of the American Dental Association suggests that periodontal disease and diabetes go hand in hand.

Patients undergoing two-year gonadotrophin treatment reported significantly improved physical, social, and psychological quality of life scores.

With mounting evidence in support of long-suspected mind-body connections, psychiatrists must consider physical activity as both prevention and treatment.

Inconsistencies between ClinicalTrials.gov and medical journals' reporting are raising questions about the editing and disseminating process.

Researchers have found a way to correct post-meal hypoglycemia in gastric bypass patients, according to a study published in Gastroenterology.

For patients with kidney transplants, a urine test could detect dysfunction easier than by invasive measures, according to a study published in the March issue of the Journal of the American Society of Nephrology.

Hyponatremia is associated with increased mortality and rehospitalization in patients hospitalized for heart failure.

The true prevalence of resistant hypertension is unknown, but it is estimated to occur in up to 20% of patients with chronic hypertension.

Researchers concluded that blood sampling analysis as the only method of diagnosis for hypogonadism is leading to under- and overdiagnosis of low-T.

Whether direct-to-consumer advertising is a good or bad thing remains a matter for debate, but what is not up for discussion is the need for due diligence on the part of physicians in managing patients who are motivated by those ads to seek medical attention.

The US Food and Drug Administration (FDA) approved Myalept, a drug form of the hormone leptin, for the treatment of lipodystrophy.

Aveed (testosterone undecanoate), an injection drug designed to combat hypogonadism, has been approved by the FDA after being rejected 3 times.

Although less than 2.4% of end-stage renal disease patients are expected to experience renal recovery, a research team found sustained recovery occurs more often than previously believed.

Despite ridicule and derision from their peers, many legitimate biomedical scientists have pursued drugs, treatments, and interventions to restore youth, extend life, or both.