Endocrinology

A review of painful diabetic neuropathy treatments concluded that, while there is no one true effective treatment for all forms of neuropathic pain, many options are still to be explored.

Reports had suggested that mitochondria in adipocytes may potentially have central roles in regulating substrate metabolism, energy expenditure, and the disposal of reactive oxygen species.

Joint inflammation could be reduced in rheumatoid arthritis patients by targeting a specific enzyme, according to research from the Washington University School of Medicine in St. Louis.

Several studies have reported that controlling blood pressure with medication improves cardiovascular outcomes.

The National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) reported that one in 10 American adults had some level of chronic kidney disease (CKD), and that kidney disease is the 9th leading cause of death in the US.

In recent years, growing understanding of diabetes has led to its recognition as a multifaceted disease that cannot simply be dichotomized into its 2 most common subgroups.

A bill before the territory's legislature would fine parents if their children are persistently overweight. Fines could reach as high as $800.

What disorders can give rise to pigmentary changes like this in an obese young man?

Several trials have been conducted, and many more are yet to be completed, that have the goal of addressing whether intensive blood glucose control and intensive blood pressure (BP) control have any long-term benefit on all-cause mortality and major cardiovascular events. Contradictory data have been published with respect to the short- and long-term benefits of aggressive BP and blood glucose control versus conventional treatments for BP and glucose control. This review presents the main points of some of the important trials to date on this subject.

The Food and Drug Administration said Friday it has approved the use of Lucentis (ranibizumab injection) 0.3 mg to treat diabetic retinopathy (DR) in patients with diabetic macular edema (DME).

How valid is the information and advice dispensed by Dr. Oz and other TV doctors?

Hypophysitis is a rare, complex condition in which inflammation infiltrates the pituitary gland. It used to be considered a condition solely affecting peripartum women, but better diagnostics have identified this condition in other patients.

Weightlifting and exercise are beneficial in an educational group for breast cancer survivors, researchers from the University of Pennsylvania determined in a recent study.

Each year, the American Heart Association's (AHA's) Scientific Sessions is the organization's largest yearly gathering of healthcare professionals and researchers in the field of cardiovascular disease and stroke. Providing 5 days of comprehensive education with more than 4000 presentations by world leaders in cardiovascular disease, the AHA 2014 Scientific Sessions featured the results of landmark and long-awaited clinical trials.

Drug therapy is recognized as an effective way to lower lipids and control hypertension, and for its effect on reducing the incidence of myocardial infarction. However, the impact of personal habits, such as eating, drinking, smoking, and exercise, on the incidence of coronary heart disease without reliance on prescription medications and their potential side effects may be less well established.

As electronic health records become more prevalent in the healthcare community, the number of software options doctors can choose from seems to range as widely as the practices themselves.

One day following sigmoidoscopy for an anal stricture, this 61-year-old obese woman was admitted to the emergency department in shock. Earlier that morning, she had a barium enema without evidence of free air inferior to the diaphragm. Acute abdominal pain developed several hours later.

As the National Institute of Health's National Diabetes Education Program (NDEP) institutes a new strategic plan, the group also welcomes a new leader who is familiar with the goals of the program.

The Food and Drug Administration has approved a new medication to improve glycemic control in adults with type 2 diabetes.

This observational cohort study from New Zealand found that "gossipy" magazines are often subtly taken from your waiting room, while the "non-gossipy" magazines remain.

Gynecomastia-the growth of breast tissue in men-can be an embarrassment for adolescents, but for professional bodybuilders it can be a career-ender. Two plastic surgeons said steroid use is to blame and surgery-not liposuction-is the best treatment.

When it comes to ordering the correct test for Vitamin D, too many doctors just can't get it right, a new study found. A Seattle team found 66% of tests ordered for one type of test were made in error, delaying care and potentially putting patients at risk. But it took the laboratory specialists 2 years of trial and error--and a lot of patience--to get the doctors to order the right tests.

According to the results of a recent study, ethnicity may play a large role in the mortality rate of patients with lupus

Researchers at Huntsman Cancer Institute (HCI) at the University of Utah recently discovered the mechanism potentially triggering pancreatic cancer from the defects resulting from extrusion, the process through which cells are squeezed out of overcrowded tissue to die.

The self-described naturopath who made millions after his dubious weight-loss product was touted as "magic" on "The Dr. Oz Show" has agreed to a multimillion-dollar settlement with the Federal Trade Commission.

Researchers recently evaluated the clinical utility of fecal concentration of elastase 1 as a means of identifying exocrine pancreatic insufficiency in patients with chronic pancreatitis.

Adult male hypogonadism (HG) is the most common form of diminished gonadal activity in men. Most clinicians prescribe testosterone replacement therapy to treat primary HG, but other therapeutic options are available.

Renal clearance can be significantly elevated in the critically ill. Treating these patients with renally cleared drugs can present a problem. Drugs-whisked through the body with greater than expected efficiency, a process called augmented renal clearance (ARC)-reach only suboptimal levels and, consequently, patients experience no improvement or actual clinical decline. ARC is often associated with elevated urinary creatinine clearance.

In March 2014, the Society of Surgical Oncology Susan G. Komen for the Cure Symposium focused on the literature on the epidemiology, molecular pathology, and therapy considerations of triple-negative breast cancer. The Annals of Surgical Oncology has published a summary of this work ahead of print.

JAMA Psychiatry has published a study ahead of print examining the relationship between PTSD and T2DM in Nurses' Health Study II participants. The study questioned whether PTSD increased the risk of T2DM among civilians, and the magnitude of change. The findings indicated a positive association.