Internal Medicine

Researchers in Saint Louis are examining the ways in which a drug already approved for multiple sclerosis could ease some of the pain associated with chemotherapy for cancer patients.

Researchers at the University of Buffalo are hoping a familiar friend from the past will help them battle some potential problems in the present and future.

Intestinal bacteria levels may be a good marker for determining risk of type 2 diabetes and obesity.

Even as recently as a decade ago, an HIV diagnosis could have been equivalent to a death sentence. But now, researchers are working to make a cure for the virus a reality.

The brains of hyperglycemic patients with Type 1 diabetes produce elevated levels of the neurotransmitter glutamate, which may increase their risk of depression.

Treatment for 12 weeks with empagliflozin led to significant reductions in HbA1c levels and blood pressure compared to placebo.

Although medications for alcohol use disorders are not widely utilized, a review published in a recent issue of JAMA highlighted several drugs that can effectively reduce alcohol consumption.

Data from a large cohort of Swedish men suggest that regular vigorous exercise starting around age 30 may increase the risk of atrial fibrillation, particularly among those who stop exercising later in life.

Patients with psoriasis could see relief from their condition following the results of a study that examined the impact of the stimulation of the aryl hydrocarbon receptor.

A retrospective cohort study of Medicare beneficiaries hospitalized for heart failure with a left ventricular ejection fraction between 30-35% found improved 3-year survival rates among those who received a prophylactic implantable cardioverter-defibrillators compared to those with no ICD.

The continuous use of macrolide antibiotics for prophylaxis is associated with a significant reduction in chronic obstructive pulmonary disease exacerbations.

Revising the definition of chronic kidney disease progression that is currently used in clinical trials could speed the development of new therapies.

A new study finds that regular exercise can boost the effect of testosterone replacement therapy among men who suffer from late-onset hypogonadism.

Though chronic obstructive pulmonary disease (COPD) exacerbations remain a top cause of US hospitalizations, 62% of patients surveyed by the COPD Foundation did not know much about them, and 16% had no knowledge on flare-ups.

New research has reached the unexpected conclusion that non-steroidal anti-inflammatory drugs (NSAIDs) may rank among the top causes of drug-induced anaphylaxis.

A recent review found that tonabersat, a novel benzoylamino benzopyran compound, is well-tolerated, but no better than placebo for migraine prophylaxis.

Men with HIV have more noncalcified plaque in their arteries than their uninfected counterparts.

Study results show hepatic decompensation is more common in people who have both HIV and hepatitis C virus (HCV) compared to those infected only with HCV, an indication that early HCV treatment among coinfected patients is needed.

Study results suggest that patients with long-term HIV who also have hemophilia may have an increased proportion of immune cells in their blood that target HIV.

Saliva tests for detecting anti–hepatitis C antibodies may not be as effective in patients who also have an HIV infection.

Scientists have mapped the structure of a hepatitis C virus surface protein that is responsible for binding to host liver cells, leading to virus entry.

Since the risk of herpes zoster rises sharply after age 50, the significant global health burden of shingles pain is expected to increase as the population ages.

Among women, financial security determines the quality of adjustment to a diabetes diagnosis.

A more effective way to track the early progression of multiple sclerosis has been developed, according to research published online in Radiology.

Study shows bariatric surgery can not only help obese patients lose weight, but also reduce their risk of developing atrial fibrillation.

Phase III trial shows that transplanted purified human pancreatic islets safely restored sustained near-normoglycemia and provided protection from severe hypoglycemia in patients with long-standing type 1 diabetes and iatrogenic hypoglycemia.

Researchers find that the ratio of total cholesterol to HDL is a significant predictor for CVD in type 1 diabetes patients who are not using lipid-lowering drugs, and that the ratio of total cholesterol to HDL is a more reliable marker for risk when considering primary prevention.

Researchers have identified a previously unrecognized mechanism for SGLT2 inhibitors in the regulation of glucagon and gluconeogenic gene expression.

Most children with hepatitis C contract the virus through transmission from their chronically infected mothers, either in the womb or at birth, particularly when an expectant mother also is HIV-positive.

Patients with type 1 diabetes who had more depressive symptoms measured at baseline and over time appear to be at an increased risk of mortality, even after allowing for likely mediators.