Internal Medicine

Glucocorticosteroids have been shown to be effective for treating chronic rhinosinusitis associated with allergic rhinitis and nasal polyps. There are several formulations of topical and oral agents available to clinicians.

Do asthma and COPD share enough characteristics such as reduced rate of airflow resulting from increased inflammation, along with similar responses to some forms of treatment, reduce the importance of differential diagnosis?

Research into the pathogenesis of chronic rhinosinusitis has shed new light on the association between asthma and CRS while also providing new insight into CRS disease endotypes, enabling clinicians to individualize treatment regimens.

Although overall mortality related to breast cancer in women is declining, patients with locally advanced breast cancer still pose a challenge to oncologists.

New evidence-based consensus recommendations provide guidance for practitioners on non-surgical treatment options that are appropriate or inappropriate for knee osteoarthritis patients.

Thomas Dayspring, MD, FACP, FNLA, NCMP, discusses the promises and pitfalls of the 2013 American College of Cardiology/American Heart Association Guideline on the Treatment of Blood Cholesterol to Reduce Atherosclerotic Cardiovascular Risk in Adults.

Family physicians should place as great an emphasis on walking as they do on monitoring medication and laboratory data, and strongly recommend increased ambulatory activity to their patients.

Researchers at Yale University have pinpointed the cells and cellular processes that trigger life-threatening pulmonary hypertension, which have been little understood until now.

Scientists have identified and blocked the trigger for autism and other mental illnesses in stem cells that test positive for fragile X syndrome.

A minimally-invasive, surgically-implanted esophagus band developed at Stony Brook University Hospital effectively reduces symptoms of gastroesophageal reflux disease (GERD).

New research suggests that chronic insomnia is a 24-hour brain condition, rather than a nighttime disorder.

A pilot program that uses text message medication reminders has led to reduced asthma exacerbations and fewer hospitalizations among participating inner-city adolescents.

During experiments with cell-to-cell and cell-free transmissions, researchers showed that existing drugs are effective in suppressing the spread of HIV.

Although the mechanisms of disease severity for this form of asthma are not fully understood, progress has been made in identifying promising targets for new treatments.

Successful applications of nanotechnology in the field of immunology will enable new generations of vaccines, adjuvants, and immunomodulatory drugs that aim to improve clinical outcomes in response in a range of infectious and non-infectious diseases.

Scientists in Sweden have identified CD14hiHLA-DRdim, which they believe is the primary macrophage responsible for the pro-inflammatory symptoms of Crohn's disease.

One patient-centered medical home pilot was associated with improvement in only one of 11 quality areas and was not associated with reductions in hospital utilization or costs of care over 3 years.

Researchers concluded the asthma drug omalizumab can be used to successfully desensitize patients with multiple food allergies

Medical researchers have suggested that dairy products protect against metabolic syndrome (MetS), decreasing the risk of diabetes, heart disease, altered glucose homeostasis, and dyslipidemia.

A 40-member coalition partly comprised of physician experts on opioid addiction treatment and overdose prevention is asking the US Food and Drug Administration to rescind its approval of extended-release Zohydro (hydrocodone bitratrate), given the drug's perceived dangers to the public.

Due to its ambiguous etiology, the low cost-to-benefit ratio associated with many laboratory tests used in assessment and diagnosis, and the low-to-moderate strength of evidence supporting many pharmacologic approaches to treatment, chronic urticaria can be one of the most difficult inflammatory skin conditions for clinicians to manage.

A review of the various guidelines on the treatment of chronic urticaria shows there is limited evidence demonstrating the efficacy of many commonly used medications, with the strongest evidence supporting the use of one or more second-generation antihistamines.

Research shows that although mast cells are key effector cells in the pathogenesis of urticaria, targeting individual mast cell mediators is often not therapeutically effective

If there is one absolute truth in medicine, it is that the truth will change over time.

With reimbursement increasingly tied to quality measures and other metrics, the question of whether best practices actually produce improved outcomes has taken on greater importance for clinicians and their patients.

Improved control of allergic rhinitis with allergy immunotherapy can mitigate the development and severity of other allergic and respiratory diseases, leading to a reduction in the use of outpatient services.

New research suggests that patients with allergic rhinitis face significantly lower risks for heart attacks, cerebrovascular disease, and all-cause mortality.

Regular consumption of white fish may reduce the cholesterol concentration, waist circumference, and blood pressure components of metabolic syndrome.

Researchers identify several independent risk factors for the development of severe and/or symptomatic hyponatremia in patients on oxcarbazepine therapy.

The missing link between environmental and genetic risk factors for type 2 diabetes suggests a new scientific approach is needed, which is where the emerging field of nutrigenetics comes into play.