Internal Medicine

A recent study from the University of Miami suggests the Moderna and Pfizer COVID-19 vaccines were not associated with reductions in any sperm parameters, including semen volume, sperm concentration, sperm motility, and total motile sperm count.

Patients with chronic kidney disease reported poor quality of life, particularly in domains related to their condition.

It could take up to 10 years to develop new treatments for inflammatory bowel disease.

This past year has brought unique challenges for sickle cell disease patients and communities of color. The ongoing vaccination campaign is yet another challenge that healthcare communities must find ways to overcome.

A sickle cell expert reflects on the state of care and access for sickle cell communities.

A personalized topical cream applied for 1 week was shown to reduce Staphylococcus areus colonization and improve clinical outcomes.

Improvements in neovascularization and best-correct visual acuity were generally not sustained following treatment discontinuance.

A randomized trial comparing 3 dietary approaches, including 2 involving fasting, suggests the recently popularized approach does not provide any substantial benefits compared to a traditional diet.

Older age, macroalbuminaria, and high diastolic blood pressure are among some of the risk factors significantly associated with onset of chronic kidney disease.

Adding platelet-rich plasma to narrowband–ultraviolet B is likely a safe, effective, and efficient means of treating atopic dermatitis.

Small molecule treatments have been historically effective at treating IBD.

More frequent testing and reduction of the rate of progression as the end point may allow investigators to more efficiently assess efficacy of glaucoma therapy.

More studies are needed to determine whether bi-level positive airway pressure ventilation can help prevent acute chest syndrome.

Data from the large-scale, population-based study corroborate previous single-center study findings.

Sustained virologic response following direct acting antiviral treatment substantially reduced the all-cause mortality rate in patients with HCV.

More than half of the patients in the study were treated for inflammatory bowel disease with infliximab.

Patients included in the study had a median of 3 prior CDI episodes and 4 risk factors for recurrent infections.

Dapagliflozin and the SGLT2 inhibitor class may have untapped potential far beyond the reduction of heart failure hospitalization risk.

Of the 44 new recommendations, 7 were strongly recommended.

A systematic review of clinical trials notes that topical eye drops may lead to favorable retinal and visual outcomes, despite heterogeneity across multiple studies.

The UNITI studies have shown ustekinumab is effective at inducing and maintaining clinical remission in Crohn’s disease patients.

The COVID-19 pandemic had forced vitiligo patients to delay treatments; however, not much is known about the effects of delaying on disease course.

Using both tests to screen for colorectal cancer was more effective than just using colonoscopies alone.

Direct-acting antivirals has increased the need to treat children HCV patients before they begin to engage in dangerous behaviors.

Misha Rosenbach, MD, gives an overview of climate change and its relevance to dermatology.

Treatment with plasminogen, human-tmvh was associated with improvements in existing lesions and prevention of new lesions in supporting data.

Vedolizumab treatment was associated with lower IMC recurrence rate after ICI resumption.

There are no guidelines on sickle cell patient referral to pulmonologists, associated outcomes, and best therapeutic interventions.

Jordana Hoppe, MD, highlights some key points about the genetic condition.

Meaningful change thresholds in POEM and DLQI scores have been established for adolescents and adults.