Multiple Sclerosis

Embattled Mylan scored a victory when Teva's patents for Copaxone were invalidated. The decision comes on the eve of a trial in which Teva will fight two other pharmaceutical companies over the right to produce glatiramer acetate treatments for multiple sclerosis.

Neurofilament lightchain level may be a biomarker for other conditions, but it is weak as an independent risk factor for multiple sclerosis, researchers report.

Early treatment benefits MS patients, another study has found.

“In this current investigation, the two most statistically significant findings were that higher HbA2 levels correlated with higher RBC levels and prominently lesser MSSS [multiple sclerosis severity score].”

RNS60, a charge-stabilized nanostructure, shows potential as a beneficial therapy for demyelinating conditions, such as multiple sclerosis (MS), according to the results of a recent study.

In a post hoc statistical analysis of data from 61 consecutive patients diagnosed with intermediate uveitis, the central foveal thickness cut-off value for starting systemic corticosteroid treatment was determined to be 215.5 μm. This value was found to have a sensitivity of 62.5% and a specificity of 96.4%.

There are differences in the tissue sodium signal and the fluid-attenuated sodium signal in the brain lesions of patients with acute multiple sclerosis (MS) and those with chronic MS, according to a recent study.

Quantitative magnetic resonance imaging (qMRI) may be a good tool for assessing disease status among patients with secondary progressive multiple sclerosis (SPMS), according to the results of a study published in the journal PLOS One

Even though almost one-quarter of the participants had suboptimal adherence, the researchers say, “we observed a higher proportion of optimal adherence than previously reported in the MS literature.”

Aquatic exercise appears to improve balance for people with multiple sclerosis (MS) and hemiplegia according to a recent review of 8 published studies. “It was concluded that exercises in water improved postural control in patients with multiple sclerosis.”

Despite limitations, the results of a new study suggest that prospective research addressing the question of reserve-related activities in patients with MS should be pursued.

“In the clinical studies, daclizumab demonstrated statistically significant benefits on clinical, radiographic, and patient-reported outcome measures in patients with RRMS.”

Researchers in Germany reviewed the use of alemtuzumab, a monoclonal antibody used to treat relapsing remitting multiple sclerosis, over the last two years and identified important first steps in patient selection, preparation, infusion courses, and monitoring.

While a low-fat, plant-based diet did not result in improvements in brain magnetic resonance imaging (MRI) of multiple sclerosis (MS) patients, it did bring about less fatigue, better body mass index (BMI) measures, and improved metabolic biomarkers

Researchers call for “major policy changes" in order to “avoid many of the long-term economic and personal costs that result from unnecessary irreversible disability.”

Venturing into largely unexplored territory, researchers from the University of Southampton conducted interviews with MS patients to determine their emotional response to their interactions with healthcare professionals, as it pertained to their prognoses. The study determines increased sensitivity, awareness, and attention may be needed among HCPs to best communicate with their MS patients.

Dimethylfumarate, a multiple sclerosis drug metabolite, could be a safe and effective therapy for Parkinson’s disease and slow its onset.

Following a diet that mirrors the habits of fasting can reduce the symptoms of multiple sclerosis.

Multiple sclerosis symptoms such as fatigue, depression, and paresthesia can be alleviated using yoga and aquatic exercises.

The multiple sclerosis immunosuppressant drug mitoxantrone might be linked to an increased risk for breast and colorectal cancer.

Researchers have identified a specific genetic mutation that may increase the likelihood of developing a rapidly progressing form of multiple sclerosis.

Fewer than half the participants in a recent study benefited from medications to treat tremor in multiple sclerosis, showing the condition is under-treated, an Alabama research team reported.

There are key differences in the gut microbial community composition in children with early-onset multiple sclerosis compared to healthy children without multiple sclerosis.

While having a number of choices to pick from when treating patients with multiple sclerosis can be advantageous there can also be challenges that need to be addressed by both doctors and patients

The past few years have seen the development and approval of a wide range of multiple sclerosis treatments. This has meant doctors have many more options when looking to help their patients.

You may have seen reports on the “treatment” on TV or heard that some of Beverley Hills’ richest citizens are raving about it, but whole body cryotherapy (WBC) doesn’t yet have the data to back up the many health benefits claimed by its boosters.

Researchers used pre-clinical models of MS, as well as samples from patients with MS, in order to demonstrate that diet and gut flora may influence the activity of astrocytes, the cells that control inflammation and neurodegeneration in the brain.

As new treatments are developed for multiple sclerosis one of the questions has become how do you measure their success. A possible metric being developed is No Evidence of Disease Activity or NEDA.

There is still much more to be learned about the effects of depression and cognitive impairment in patients with multiple sclerosis but there are steps being taken to address these issues and help better inform patients of the impact both can play in their lives.

Patients diagnosed with multiple sclerosis may feel their cognitive abilities slip in their everyday lives but without the proper testing their level of impairment may not be properly diagnosed.