Ophthalmology

Baseline evidence of deep capillary nonperfusion in eyes with clinically referable NPDR may predict short-term complications with high accuracy.

Investigators stress the need for timely surgical intervention to ensure favorable visual outcomes in patients with severe complications, including retinal detachment and vitreous hemorrhage.

Investigators from the University of Pennsylvania suggest the associations, particularly beta peripapillary atrophy, and tilted optic discs, should be accounted for when investigating glaucoma in high-risk black populations.

Age less than 3 months at surgery was associated with an elevated risk of glaucoma-related adverse events in aphakic eyes, but children with pseudophakia were less likely to develop a glaucoma-related adverse event.

An analysis of the China Stroke Primary Prevention Trial revealed the correlation was more notable when stratified by triglycerides levels and smoking status.

A nationwide study from the United Kingdom identified a low overall prevalence of stress-induced burnout by cataract surgery but reported a reduction in the feelings of personal achievement and a significant proportion willing to give up surgical responsibilities.

An analysis of the NIH All of Us Research Program suggests patients with glaucoma did not fare worse during the early stages of the COVID-19 pandemic, but still endured stress, social isolation, and probable depression.

Results of the LAMP2 trial indicate a delay of myopia onset and progression, rather than prevention, with 0.05% atropine eyedrop use, leading study investigators to call for further research.

Announced by Regeneron, aflibercept injection is the first FDA-approved pharmacologic treatment for preterm infants with ROP.

New 6-month findings from a First-in-Human glaucoma treatment trial indicate the drug delivery platform continued to show a 45% reduction in mean intraocular pressure.

Aflibercept treatment resulted in statistically significant anatomic improvement, but no improvement in visual acuity among patients with NPDR without CI-DME at 4 years of analysis.

In a Dutch population, greater sedentary behavior was associated with an increased risk of DED, but data suggest the association was only significant for those with less than recommended physical activity.

Two-year data suggest the average cost of aflibercept monotherapy was approximately $26, 500 compared with approximately $14, 000 for the bevacizumab-first group in eyes with center-involved DME.

The FDA and CDC are urging the immediate discontinuation of EzriCare Artificial Tears as they investigates a multistate cluster of potential bacterial contamination.

The geographic range of practitioner to million persons has increased since 2007, with disparities in practitioner distribution associated with lower socioeconomic status.

A lower DME resolution rate was associated with a thicker baseline CST and better baseline best-corrected visual acuity in eyes treated with aflibercept.

Repeated injections with preoperative povidone-iodine application was associated with reduced meibomian gland loss, increased tear volume, and reduced signs of inflammation.

Eyes treated with pegcetacoplan showed a significantly slower GA lesion progression rate compared with sham, and slower growth rate toward the fovea.

6-year results from the LiGHT trial suggest SLT is a safe treatment for eyes with open-angle glaucoma and ocular hypertension, providing drop-free IOP control.

Hydroxychloroquine dosing higher than 6 mg/kg was associated with a 15-year risk of nearly 22%, while retinopathy risk with shorter duration of use was significantly lower.

An analysis of a commercial claims database offers insight into the increase in vision-threatening eye disease among people with diabetes aged younger than 65 years from 2009-2018, with results also detailing trends in anti-VEGF therapy during the same period.

The research suggests additional glaucoma surgery was required more frequently after trabeculectomy than after Baerveldt glaucoma implant surgery.

Circumpapillary structure measurements showed a dose-dependent increase with the induction of negative pressure.

Eyes with concurrent uveitis in a Swedish cohort had worse BCVA prior to and following cataract surgery, although visual improvement was greater compared to control eyes.

Based on 2021 data from NHATS, vision impairment is more prevalent among those who are older, Hispanic, non-White, less educated, and lower income.

Higher preoperative visual acuity in patients with dTRD was associated with higher vision after PPV, suggesting the importance of early intervention.

Five years of treatment follow-up in the Fight Retinal Blindness registry provided evidence that SRF protected against the development of subfoveal and extrafoveal macular atrophy.

Both rates of macular vessel density loss and ganglion cell complex thinning are associated with central visual field loss in eyes with early glaucoma.

A post-hoc analysis suggests that increased dietary nitrate intake was associated with a decreased risk of late AMD, but this association was attenuated after the addition of plant-based dietary patterns.

A group of investigators, researchers and policymakers discuss the issues, innovations and aspirations that may define 2023 advances.