Rheumatoid Arthritis

There are five different tumor necrosis factor (TNF) inhibitors available for the treatment of RA. Researchers say that despite showing similar efficacy, they differ in molecular structures and signaling disruption.

Johns Hopkins researchers have linked a specific bacteria involved in gum disease to the processes at hand in rheumatoid arthritis. It may be premature, however, to consider flossing an aspect of joint health.

Autoimmune disease has been known to increase the risk of epilepsy, but it's new knowledge that a mother's rheumatoid arthritis impacts their offspring's epilepsy risk.

“This is a subset of the RA population that we should probably give intensive treatment to," Dr. Harrold says of RA patients diagnosed with certain prognosis factors. "Not only clinical adverse sequelae, but also in their social environment, like being able to work or function.”

Asked to assume equal cost-effectiveness, the patients were given eight facets of treatment and asked to rank them between 1 and 8, with 1 being the most important to them and 8 being the least.

Researchers who evaluated adverse events in a large sample of patients taking NSAIDs for arthritis came to a surprising conclusion: celecoxib is the safest of three drugs studied.

Used for treatment of inflammation in rheumatic diseases, glucocorticoids are known to cause osteoporosis. The American College of Rheumatology has put forth new recommendations to hopefully decrease the frequency of bone fractures.

Prescribing rheumatologists discussed drug interactions, costs, contraindications, and severity of side effects with less than 50% of the patients in the study to whom they had prescribed disease-modifying antirheumatic drugs.

With ever-growing data that the inflammation in rheumatic conditions can go hand-in-hand with cardiovascular inflammation, two different studies seek to broaden rheumatology’s approach to dangerous conditions it may influence.

A new study out of Ireland examined the prevalence of extra-articular manifestations in axial spondyloarthritis, and found that women were at significantly higher risk for inflammatory bowel disease and uveitis than men.

Certain types of inflammation go hand-in-hand. Columbia University researchers hypothesized that treatment that lowered arthritis disease activity would also decrease the risk of heart failure.

A single-center cross-sectional study has found elevated rates of fibromyalgia in patients with various forms of arthritis, including psoriatic arthritis. It joins previous studies that observed that the two painful conditions sometimes coincide.

Researchers from the UK say they have developed a blood test that can detect osteoarthritis and rheumatoid arthritis long before painful symptoms become noticeable.

Sirukumab, a rheumatoid arthritis treatment that has performed well in recent studies, is now awaiting approval in both the United States and Europe.

The FDA today approved its fourth biosimilar, a tumor necrosis factor inhibitor similar to adalimumab.

Erelzi, a biosimilar of Enbrel (etanercept), has received FDA approval. Biosimilars are defined by the organization as being “highly similar to an FDA-approved biological product” while demonstrating “clinically meaningful differences in terms of safety and effectiveness.”

Roughly 20% of people with rheumatoid arthritis (RA) also suffer from chronic kidney disease (CKD), though no clear explanation exists as to whether or not that is coincidental.

Enthesitis refers to the instance of inflammation at the point where a tendon joins to a bone. Looking for further insight into the mechanisms behind inflammatory rheumatism, researchers from delved into the roots of Achilles enthesitis and may have emerged with a new approach to treating many rheumatic conditions.

Atop a growing body of research that examines how rheumatoid arthritis (RA) symptoms are dictated by the body’s circadian rhythms, a recent study seems to explain why so many people-RA sufferers included-wake up each day with stiff joints.

Interleukin-1β (IL-1beta), a cytokine that plays in important role in the body’s immune response, turns out to be part of the body’s early defense system for bacterial infections. Anti-inflammation treatments for autoimmune conditions like rheumatoid arthritis (RA) often times inhibit IL-1beta to mitigate the inflammation that it initiates when infection is detected.

The blistering pace of mobile innovation has opened countless doors for clinical application. Built on Apple's ResearchKit platform, GSK's PARADE app seeks to study rheumatoid arthritis patients in their daily lives.

Patients with psoriasis, psoriatic arthritis, and rheumatoid arthritis still face challenges research has yet to meet, according to the authors: “Given the commonality of comorbidities across all three diseases, there is a degree of overlap in their management.”

A review of well over 100,000 patients in Texas found that breast and prostate cancer patients with rheumatoid arthritis lived roughly two years less than those without.

A pair of recent studies look in an interesting place to find commonality among rheumatoid arthritis sufferers: their guts.

Professor Aida Babaeva compared cardiovascular effects of immunotherapy plus standard treatments to those evident with the standard treatment alone, claiming the anticytokines doubled chances of reaching target blood pressure and more than halved risk of cardiovascular events.

A new study finds electronic stimulation from implantable bioelectronic devices capable of reducing production of inflammatory agents in rheumatoid arthritis sufferers, a finding its authors consider groundbreaking.

Saying the Guidelines fill a “significant clinical void,” the organization celebrated awareness of the rheumatic condition with a series of stringently approved recommendations for its treatment.

The US Food and Drug Administration's (FDA's) Arthritis Advisory Committee recently voted unanimously to recommend the approval of biosimilars to adalimumab (Humira) and etanercept (Enbrel).

You may have seen reports on the “treatment” on TV or heard that some of Beverley Hills’ richest citizens are raving about it, but whole body cryotherapy (WBC) doesn’t yet have the data to back up the many health benefits claimed by its boosters.

Analysis of a Danish registry found that a switch from infliximab (Remicade) to a biosimilar called Remsima did not appear to change disease activity status or increase the risk of flares in patients with psoriatic arthritis or rheumatoid arthritis.