Rheumatology

Authors call for further investigation of pathophysiological pathways between rheumatoid arthritis and primary open-angle glaucoma.

Iberdomide, a high-affinity cereblon modulator, works by affecting leukocyte development and autoimmunity.

Limited physical function, fatigue, mental health issues (resulting from chronic disease), and medication issues can further affect the ability of children with rheumatic disease from performing well in school.

Recent studies suggest that a gap in cardiovascular risk remains between patients with rheumatoid arthritis and the general population.

A retrospective study analyzed patients with systemic sclerosis to determine prevalence, severity, and mortality within this patient population.

The Director of Policy and Advocacy for the US Pain Foundation addresses the important changes made to the updated draft of the CDC Clinical Practical Guideline for Prescribing Opioids 2022.

“Understanding the impact of axSpA on pregnancy outcomes is a vital component of improving management of women with axSpA at every stage of their lives,” investigators stated.

Authors of the study on PRP in knee osteoarthritis addressed the concerns shared by physicians in response to the method of their research.

Treat-to-target is a key strategy used in the treatment of many chronic conditions. Test your knowledge of its use in rheumatoid arthritis.

Because Sjögren's Syndrome is often undetected or misdiagnosed, investigators developed the Sjögren's Syndrome Screening Questionnaire (SSSQ).

New data support the continued assessment of the investigative drug for adults with SLE.

Investigators in Israel perform the largest retrospective review of patients with rheumatic fever in a developed country, spanning 25 years of research.

The rationale for using a newer monoclonal antibody therapy, anifrolumab, to manage patients with systemic lupus erythematosus.

Indications for belimumab, a monoclonal antibody, as therapy for patients with systemic lupus erythematosus.

The results lead investigators to question the usefulness of prehabilitation before total knee replacement to improve functional outcomes in patients with osteoarthritis.

“Incorporating patient perspectives will not only help better tailor therapies in this heterogeneous population but also identify treatment targets that are relevant to the individual patients," investigators explained.

ACR partners with the Vasculitis Foundation to establish a new guideline that addresses diagnostic issues relating to Kawasaki disease, a rare vasculitis that inflames the blood vessels.

With several targeted therapies demonstrating positive trial results in lupus nephritis, the treatment paradigm appears to be shifting.

“Access to mental health services is a critical component of comprehensive care for patients suffering from rheumatologic disease,” investigators stated.

Methotrexate is the first-line treatment for rheumatoid arthritis. As with all drugs, there is a risk of experiencing adverse effects. Do you know what type of adverse effects are most likely with methotrexate and who is likely to experience them? Take this quiz to find out.

Karen Onel, MD, one of the lead investigators of the ACR's recent JIA treatment guidelines updates, explains important changes, treating patients with glucocorticoids, and the continued unmet needs in pediatric rheumatology.

Free or total 25(OH)D serum levels were not associated with psoriasis disease severity in this small study of biologic-naïve patients.

Take 5 minutes to catch up on Rheumatology Network's highlights from the week ending March 12, 2021.

Investigators examined the effect that pulsed low-intensity ultrasonography had on symptom relief and tibiofemoral articular cartilage thickness among patients with knee osteoarthritis.

Trauma patients and patients treated with combination ABX therapy were at an increased risk of C difficile infections.

“Kawasaki disease continues to be an area of evolving understanding in clinical treatment,” said Mark Gorelik, MD, lead investigator of the guideline.

Daniel J. Lovell, MD, MPH, explains the recent ACR guidelines updates regarding the treatment and management of juvenile idiopathic arthritis and the clinical significance of the changes.

Resources that can help educate patients with lupus about their diagnosis and encourage them to take a more proactive role in self-care.

Types of tests used to evaluate patients for signs of lupus or disease progression.

Roy Fleischmann, MD, discusses the usage of biosimilars in the United States and hypothesizes about what is in store for the future.