Ulcerative Colitis

Patients can control and reduce their risk for contracting colon cancer and colitis by maintaining a balance of two major isoforms, according to findings published in the journal eLife.

The development of new medications for any condition requires attention to detail in a number of areas, especially safety and efficacy. A recent drug developed for irritable bowel syndrome (IBS) looked to be effective in both areas prior to its approval.

The new Rome IV criteria classify the functional bowel disorders into five distinct categories, including irritable bowel syndrome (IBS), functional constipation, functional diarrhea, functional abdominal bloating/distention, and unspecified functional bowel disorder. A new category for opioid-induced constipation, which is distinct from the functional bowel disorders, has been added.

Rome IV updates include more specific definitions and diagnostic criteria for functional gastroduodenal disorders such as functional dyspepsia, belching disorders, and nausea and vomiting disorders.

The Rome Foundation announced the release of updated and revised Rome IV diagnostic criteria for more than 20 different gastrointestinal disorders at DDW 2016.

Endoscopic retrograde cholangiopancreatography is a common procedure in adult patients but a recent study looked at whether the procedure was safe for younger patients and whether it provided the same level of efficacy.

Golimumab injections continue to prove effective and safe for patients with moderate-to-severe ulcerative colitis, according to a recent study.

Treatment isn’t enough to keep ulcerative colitis relapses at bay; dietary factors play in an important role in flares as well. New research identifies foods that patients should stay away from.

Patients who stop infliximab 12 months after they started are at higher risk of relapse if those patients earlier had ulcerative colitis.

Could a special type of intestinal cell be at the root of inflammatory bowel disease? Researchers from Rutgers University Newark (RU N) believed so, and wanted to determine how to alter the cells’ behavior to eliminate the disease.

Using fecal microbiota transplants (FMT) has sent ulcerative colitis (UC) patients into remission, reported a presentation given at the European Crohn’s and Colitis Organization (ECCO) Congress.

A recent fecal matter transfer (FMT) transferred non-pathogenic viruses from a healthy patient to three pediatric ulcerative colitis patients, according to findings published in mBio.

Microbial changes are a contributing factor to inflammatory bowel disease (IBD) development, according to findings published in Cellular and Molecular Gastroenterology and Hepatology.

The pharmaceutical company Shire won a patent trial concerning mesalamine (Lialda), an ulcerative colitis drug, according to a company press release.

Researchers have developed a fast, simple, and minimally invasive screening test for ulcerative colitis that uses infrared technology.

Inflammatory bowel diseases (IBD) may be countered with worm infection in the gut microbiome, according to successful mice and human studies presented in the journal Science.

Tofacitinib (Xeljans/Pfizer), an oral ulcerative colitis (UC) drug, successfully met key endpoints in two Phase III studies enrolling adult patients with moderate to severe active UC.

Previously associated primarily with assessing blood alcohol level, breath tests can now aid in accurately distinguishing irritable bowel syndrome (IBS).

Men diagnosed with multiple sclerosis often have higher blood pressure than women, in addition to higher levels of diabetes, epilepsy, depression, and anxiety.

Medical economists estimate Crohn's disease is responsible for $3.48 billion in total national costs (expected to increase to $3.72 billion in 2025).

The presence of anti-microbial antibodies that have accumulated for years before a person is diagnosed with Crohn’s disease spells complications and a difficult course of treatment.

During a fecal matter transfer (FMT), non-pathogenic viruses were transferred from a healthy patient to three pediatric ulcerative colitis (UC) patients, according to findings published in mBio.

Rare structural variants in genes could be contributing to the pathogenesis of ulcerative colitis.

Using a minimally invasive screening method for ulcerative colitis (UC) is a quick and cost-effective approach to disease detection.

Anorexia nervosa, chronic fatigue syndrome, and irritable bowel syndrome (IBS) might not be the typical threesome, but these three conditions do share a common origin.

The FDA has approved Inflectra (infliximab-dyyb/Celltrion, Inc), the biosimilar for Remicade (infliximab) for the treatment of patients suffering from serious autoimmune diseases.

Autoimmune diseases like rheumatoid arthritis (RA) and Crohn’s disease are “gonna be defeatedâ€, according to findings published in the Proceedings of the National Academy of Sciences.

The field of gastroenterology is as wide as the the amount of the body that it covers. Because of this there are certain challenges doctors face whether they treat the entire gastrointestinal system or just specific parts.

For patients dealing with a variety of conditions fecal microbiota transplantation may be the best option for treatment. Explaining the procedure to patients can sometimes be a delicate conversation for doctors with good results so far.

As the treatment for Crohn's disease moves away from steroids and surgery and towards less severe and more effective medications patients with the condition can look forward to a higher quality of life than they had in the past.