The HCPLive conference coverage page features articles, videos, and expert-led live coverage from major medical meetings throughout the year.
SEQUOIA-HCM Substudy Details Effects of Aficamten on Cardiac Structure and Remodeling
Ahmad Masri, MD, MS, discusses the results of a SEQUOIA-HCM substudy leveraging cardiac magnetic resonance to assess structural changes associated with aficamten use in HCM.
ESC Congress Study Highlights Safety of Aficamten in Hypertrophic Cardiomyopathy
Ahmad Masri, MD, MS, discusses an integrated safety analysis of aficamten using data from 3 clinical trials.
Siddharth Patel, MD, MPH: Abelacimab Could Help Reduce Procedure-Related Bleeding
Siddharth Patel, MD, MPH, discusses how an AZALEA-TIMI 71 analysis presented at ESC Congress 2024.
EMPACT-MI Kidney: SGLT2 Initiation Can Preserve Kidney Function in Post-MI Population
EMPACT-MI study shows empagliflozin is safe post-acute MI and reduces heart failure events, with kidney protection across kidney function levels.
Don't Miss a Beat: Finerenone's Role in Heart Failure from ESC Congress Data
In this episode, Muthiah Vadugnathan, MD, MPH, and Stephen Greene, MD, discuss finerenone and MRA data from ESC Congress 2024.
PALISADE: Plozasiran Offers Hope for Treating Familial Chylomicronemia Syndrome
ESC 2024: Phase 3 PALISADE trial shows plozasiran significantly lowers triglycerides and pancreatitis risk in FCS; NDA planned by year-end.
Kausik Ray, MD, MPhil: INTERASPIRE and the Expanding Knowledge Base for Lipoprotein(a)
Kausik Ray, MD, MPhil, discusses the results of the INTERASPIRE study and how it improves our understanding of the effects of elevated Lp(a).
Long-Term Data from ESC 2024 Reinforces Safety, Efficacy Profile of Mavacamten in oHCM
MAVA-LTE trial data show mavacamten's sustained benefits in symptomatic obstructive HCM, with long-term improvements in LVOT, NT-proBNP, and quality of life.
FINEARTS-HF: Finerenone Could Find Role as Second Pillar in HFmrEF/HFpEF
FINEARTS-HF results suggest finerenone may join SGLT2 inhibitors as a second pillar in treating HFmrEF/HFpEF, cutting total heart failure events by 16%.
OCEANIC-AF: Asundexian Patients Have Nearly 4x Stroke, Embolism Risk vs Apixaban Patients
Asundexian failed to prove noninferiority to apixaban for its primary efficacy outcome in the phase 3 OCEANIC-AF trial.
Rahul Aggarwal, MD: Sotagliflozin Benefit Grows with Increasing Diabetes Duration
Rahul Aggarwal, MD, discusses the findings of a SCORED analysis examining sotagliflozin's effects based on diabetes duration.
FLOW: Semgalutide Provides Consistent CV Benefit Across Spectrum of Kidney Disease
Kenneth Mahaffey, MD, discusses FLOW trial data showing semaglutide improves cardiovascular outcomes in patients with type 2 diabetes, regardless of CKD severity.
M-TEER Reduces Cardiovascular Risk, Improves Quality of Life in HF with Mitral Regurgitation
RESHAPE-HF2 shows mitral transcatheter edge-to-edge repair (M-TEER) reduces heart failure hospitalizations and improves quality of life vs optimal medical therapy alone.
Single Blood Test Could Predict Cardiovascular, Stroke Risk in Women for Up to 30 Years
A single blood test using hsCRP, LDL-C, and Lp(a) levels can predict cardiovascular risk for women up to 30 years, emphasizing personalized care.
In Women, History of Cancer Linked to Subclinical Atherosclerosis
Sara Diaz Saravia, MD, discusses a study from ESC Congress 2024 examining the utility of cancer history in women as a predictor of subclinical atherosclerosis.
Common Pitfalls to Avoid When Interpreting Clinical Trials, with Deepak Bhatt, MD, MPH, MBA
Deepak Bhatt, MD, MPH, MBA, discusses common pitfalls for clinicians when interpreting trial data based on a presentation he led at ESC Congress 2024.
Endometriosis Linked to Elevated Risk of Heart Attack, Stroke in Women
Women with endometriosis experienced a 20% greater risk of cardiac outcomes compared with women without endometriosis.
STOP-or-NOT: No Benefit to Discontinuing RASi Prior to Major Surgery
The STOP-or-NOT trial found similar outcomes for continuation or discontinuation of RAS inhibitors before noncardiac surgery, supporting individualized decision-making.
Vutrisiran Reduces Cardiovascular Risk, Improves Quality of Life in ATTR-CM
HELIOS-B trial shows vutrisiran reduces all-cause mortality and CV events in ATTR-CM, with benefits consistent regardless of tafamidis use.
ABYSS Trial: No Difference in Outcomes Continuing or Stopping Beta-Blockers Following MI
The ABYSS trial suggests no clear benefit of continuing beta-blockers post-MI in patients with preserved LVEF, echoing REDUCE-AMI findings.
Smoking Cessation Halves MACE Risk, Reduction Offers Little Protection
Patients with stable CAD who quit smoking reduced the risk of a major event by nearly 50%, while a reduction in smoking habits demonstrated minimal effects.
ESC Congress 2024 Lipidology Preview, with Professor Kausik Ray
Kausik Ray, MD, discusses what trials and new data in lipidology he is most looking forward to from the upcoming ESC Congress.
Diabetes Dialogue: Sotagliflozin for T1D and Other ADCES 2024 Highlights
This episode focuses on sotagliflozin in type 1 diabetes and other highlights from the ADCES 2024 annual meeting.
Laurence Sperling, MD: Navigating the Changing Landscape of Lipidology
Laurence Sperling, MD, offers perspective on multiple topics within the evolving field of lipid management and dyslipidemia.
Diabetes Dialogue: Navigating ADCES 2024
The first of 2 episodes on ADCES 2024, this episode focuses on sessions and presentations hosts Isaacs and Bellini participated in during the meeting.
ESC Congress 2024 Clinical Trials to Watch, with Deepak Bhatt, MD, MPH, MBA
Deepak Bhatt, MD, MPH, MBA, discusses 7 trials to watch from hotline or late-breaking sessions at the upcoming European Society of Cardiology Congress 2024.
Previewing the Family Heart Global Summit, with Laurence Sperling, MD
Laurence Sperling, MD, provides an overview of the Family Heart Global Summit, including previewing the meeting and discussing where interested attendees can learn more.
Brett King, MD, PhD: Value of LEVEL UP Data and Pushing New Standards in Dermatology
Brett King, MD, PhD, discusses the LEVEL UP trial and how it represents the field of dermatology's desire to advance care and advocate for new standards of care.
Sickle Cell Disease Linked to Higher Risk of Retinal Vascular Occlusion
Patients with hemoglobin SS sickle cell disease type may experience a significantly elevated risk of retinal vascular occlusion.
Fathers with Type 1 Diabetes May Be More Likely to Pass on Disease than Mothers
An analysis of more than 11,000 people with T1D found people were more likely to report an affected father than an affected mother.