The HCPLive conference coverage page features articles, videos, and expert-led live coverage from major medical meetings throughout the year.
Budesonide/Formoterol Considered for As-Needed Asthma Therapy in Phase 3 Studies
The longtime therapy Symbicort was tested for safety and efficacy versus SABA in 8000-plus patients on an as-needed treatment basis.
Resurgence of Black Lung Disease in Coal Miners
Miners who have worked 10 or more years are at greater risk for developing black lung disease and progressive massive fibrosis.
Medicaid Expansion Associated with Decline in ICU Stays, Early Increase in Insurance Rates
Under Medicaid expansion, declines in ICU admission may mean that increased access to insurance has led to improvements in clinical outcomes.
NORD Lifetime Achievement Award Winner: Don't Be Afraid to Take a Chance
Dr Campbell wins NORD Lifetime Achievement Award and discusses key points in rare disease.
Antibiotics Lengthen Hospitalization, Costs for Asthma Exacerbation Patients
The administration of the treatment to asthma patients is fairly common, despite guidelines advocating against it under certain circumstances.
Quitting Smoking, Not Cutting Back, Linked to Better Lung Health
Smokers who quit had lower disease risk than the group identified as stable, low-rate smokers.
Dupilumab Manages Asthma Symptoms, Reduces OCS Dosing in QUEST, VENTURE Trials
Sanofi and Regeneron reported promising results from a pair of pivotal phase 3 trials for the investigative add-on therapy.
GBS|CIDP Foundation International: Working to Ensure No One Suffers Alone
At NORD’s 2018 Rare Impact Awards, Rare Disease Report® sat down with Estelle Benson, founder of GBS|CIDP Foundation International, to discuss what the organization is doing to fight GBS.
Socioeconomic Status, Racial Disparity at the Heart of US Pollution
From food deserts to hazardous jobs that inhibit exposure and limit the means to prevent it, people of low SES are at greatest environmental health risk.
Prenatal Vitamin C Can Protect Infants' Lungs from Mother's Smoking Habits
Researchers intend to follow observed infants into early childhood to gauge the vitamin's influence on pediatric asthma rates.
Acute Blood Allergy Testing Associated with Fewer Pediatric Asthma Hospitalizations
Children given immunocap radioallergosorbent tests when hospitalized for asthma avoided re-hopsitalization twice as long as children not given the test.
Flavonoids May Slow Lung Function Decline Specifically in Never, Ex-Smoker Population
A type of flavonoid found in dark-pigmented fruits like red grapes and blueberries may slow the lung function decline that occurs with aging.
Fluticasone Furoate Gets FDA Approval for Pediatric Asthma Maintenance
The inhaled corticosteroid from GSK is indicated for pediatric asthma patients aged 5-11 years old.
Mediterranean Diet Limits Deaths Associated with Pollution Exposure
Older people adhering to the antioxidant-rich diet were less likely die from cardiovascular conditions when exposed to greater ambient air pollution.
Mepolizumab COLUMBA Study Reports Consistent 3-Plus Year Benefits
The monoclonal antibody reported quick and consistent exacerbation rate reduction in patients with severe eosinophilic asthma.
Trelegy Ellipta IMPACT Results Bolster Results Versus Dual Therapies
The once-daily, triple-drug inhaler therapy reported improvements in exacerbation rate and risk to first event.
Multidisciplinary Pulmonology Clinic Improves Low-Income Patient Access
Over 16 months, a greater rate of patients reported returning visits, proper inhaler use understadning, and overall satisfcation.
Inpatient Opioid Use May Increase Outpatient Opioid Prescription Use
Reducing use of opiates near the end of hospital stay, especially 24 hours prior to discharge, may reduce outpatient prescription of opioids.
In Utero Household Air Pollution Exposure Increases Infants' Risk of Poor Lung Function
Infants whose mothers were exposed to carbon monoxide in the second and third trimester were at highest risk for reduced lung function when they were tested at 1 month of age.
CPAP Shows Heart Rate Reduction for OSA Patients with Prediabetes
The therapy showed reduction in nighttime resting heart rate comparable to that of beta blockers.
Increased Risk of Asthma Development Linked to Ozone Exposure at Birth
The hazard ratios for ozone measured at bone as a single pollutant showed statistically significant higher risks for development of asthma, allergic rhinitis and eczema.
FoundationOne CDx: A Broad Companion Diagnostic Test for Cancer Tumors
Vincent Miller, MD, chief medical officer of Foundation Medicine, discusses FoundationOne CDx, an FDA-approved diagnostic that is clinically validated for solid tumors.
How GSSI, A Nonprofit, is Fighting Gastroparesis
Patrick Dunegan, Rare Impact Awardee, explains how GSSSI, a 501c3 nonprofit organization, is working to fight gastroparesis, a gastric motility disorder known to be very debilitating for those who suffer from it.
Vivek Patel, MD: Retinal Pathology and Alterations in the Brain
Researchers are using hi-def retinal and neuroimaging techniques to elucidate the relationship between pathology in layers of the retina and downstream brain alterations.
Dabigatran Improves Cardiovascular Outcomes After Noncardiac Surgery
Patients treated with dabigatran following myocardial injury after noncardiac surgery were 20% less likely to die of a cardiovascular cause.
Lofexidine Phase 3 Studies Demonstrate Reduced Opioid Withdrawal Symptoms
The data may be helpful for clinicians in developing treatment courses for patients exhibiting withdrawal symptoms from short-acting opioids.
David Walling, PhD: Misconceptions and New Developments Around Schizophrenia
David Walling, PhD, discussed the biggest misconceptions about patients with schizophrenia, including the high rate of suicide among this population.
Self-Reported Functioning Measures in MDD Patients Identifies Working Patients With Impaired FC
Employed patients who were also impaired on functional capacity measures, showed larger overall treatment response than unemployed patients regardless of functional capacity measure scores.
Cocaine, Marijuana Use Linked to Worse Myocardial Infarction Mortality Outcomes
Patients who abused substances reported significantly greater cardiovascular and all-cause mortality risk from type 1 MI — despite also reporting lower risks for traditional factors.
David Walling, PhD: Aripiprazole Lauroxil NanoCrystal Dispersion for Schizophrenia
David Walling, PhD, discussed the results from a pharmacokinetic and safety study that evaluated aripiprazole lauroxil NanoCrystal Dispersion therapy initiation.