The HCPLive conference coverage page features articles, videos, and expert-led live coverage from major medical meetings throughout the year.
CP101 Prevented Recurrence of C Difficile Infection in PRISM-EXT Trial
Data show the proportion of individuals with sustained clinical cure through Week 8 was 80.3% with CP101 treatment.
Guiding Appropriate Ketamine, Esketamine Use in Psychiatry
The lead author of treatment recommendations weighs in on their current use and future research.
Raseen Tariq, MBBS: FMT for Refractory Host Versus Graft Disease
Initial studies have shown a 73% efficacy for FMT in treating patients with HVGD.
Lack of Association Observed Between BMI and Mortality Among C Difficile Hospitalizations
BMI did not have an association with increased risk for death in any BMI category, according to study investigators.
Miguel Regueiro, MD: Safety Data on Ozanimod for Ulcerative Colitis
A look into the efficacy of ozanimod in patients with UC and the potential risk for cardiovascular events.
SER-109 Results in Increase in Microbe-Producing Metabolites
The live microbiota therapeutic has shown promise in treating patients with recurrent CDI.
Taha Qazi, MD: Male Sexual Dysfunction Following Ulcerative Colitis Surgery
Patients who have IPAA are more than twice as likely to suffer from male sexual dysfunction.
TNF-Antagonist Therapy Linked to Better Outcomes for Post-Operative Crohn’s Disease
Patients treated with TNF- antagonists had a higher deep remission rate compared to patients treated with ustekinumab.
DDW Research Shows No Efficacy for Vedolizumab in Treating NAFLD
Patients with IBD are often at an increased risk of developing NAFLD.
Bariatric Surgery Linked to Improved Outcomes After Myocardial Infarction
New data from DDW 2022 show inpatient mortality rates were lower in patients with history of bariatric surgery.
Ken Blount, PhD: Effect of RBX2660 on Microbiome and Bile Acid Composition
Dr. Blount discusses the DDW 2022 poster of distinction on the investigational live biotherapeutic.
How Evolving Psychiatric Definitions Set the Tone for Care
Amid significant psychotherapy innovation and consideration to broader aspects of mental illness definition, Jonathan Alpert, MD, PhD, emphasizes the need for improved clinical trial standards.
Long-Term Assessments Needed to Evaluate Impact of Accelerated Aging on EoE Progression
Post-treatment, data show molecular age remained significantly greater than chronological age at a median difference of 18.6 years.
Adjunctive Cariprazine with Antidepressants Benefits Adult Major Depressive Disorder
New phase 3 data presented at APA 2022 support the agent as an adjunctive in older patients without benefit from monotherapy antidepressant medication.
Ustekinumab, Ozanimod Have Comparable Profiles for Ulcerative Colitis
The data presented at DDW show similar safety and efficacy for the 2 treatments.
How Mental Illness Definitions Are Still Being Uncovered and Refined
Montefiore psychiatry chair Jonathan Alpert, MD, PhD, discusses suggested updates to the DSM-5—with consideration to social determinants and patient-reported functioning.
RBX2660 Reduces Risk of CDI Recurrence at Week 8
Recurrence commonly occurred during the first 2 weeks regardless of treatment.
The Pediatric Disaster Psychiatry Care Team
Linda Chokroverty, MD, discusses the significance of timing, communication and care coordination when children are affected by disasters or trauma.
Understanding Socially-Determined Mental Health and the Impact of COVID-19
APA president-elect Rebecca W. Brendel, MD, JD, discusses the need to prepare for a "twin mental health pandemic" while continuing to appropriately facilitate innovations in psychiatric care.
Zuranolone Benefits Major Depression, Postpartum Depression in Clinical Program
Anita Clayton, MD, reviews the available phase 2 and 3 clinical data for the novel, once-daily oral investigative drug.
The Need for Disaster Psychiatry Care
Linda Chokroverty, MD, discusses the role psychiatrists play in managing the mental health effects of disasters, and how children specifically may be impacted.
Acid Suppression Results in a Decrease in Mortality for GERD Patients Following Lung Transplantation
Both post-transplant PPI and histamine-2 receptor antagonist use were independently associated with reduced risk of 1-year mortality.
Eco-Anxiety and Contributing Mental Health Factors Among BIPOC
A pair of psychiatrists discuss how climate change and other social determinants of health are affecting the mental wellbeing of indigenous people.
Higher Adherence to DASH Diet Linked to Stronger Protection Against NAFLD Risk
DASH diet was inversely associated with NAFLD risk, independent of BMI changes.
Ribavirin Not Effective, Safe for Genotype 3 HCV
The treatment did not improve sustained virologic response but did increase the rate of treatment-related adverse events.
Anti-TNF, Ustekinumab Have Similar Efficacies Against Crohn’s Disease
There remains a need for longer-term observational studies comparing the 2 treatments.
Who Makes Up the Modern Dementia Care Team?
It takes even more than a village to provide the comprehensive care needed for aging, neurocognitive patients, says Rajesh R. Tampi, MD, MS.
Second-Generation Long-Acting Injectables Significantly Improve Long-Term Severe Schizophrenia Outcomes
A 6-year mirror analysis of risperidone, once-monthly paliperidone palmitate or once-monthly aripiprazole concludes suggesting the regimens may serve as an alternative to clozapine.
Franziska Trudzinski, MD: Identifying Gender-Specific Pulmonary Disorders in COPD
Dr. Trudzinski speaks of the importance of diagnosing sex-specific pulmonary and extra-pulmonary comorbidities in women with COPD, as well as the lack of research regarding COPD prevalence in women.
MRx-4DP0004 Well Tolerated in Adult Patients with Asthma
Safety and efficacy data for the oral asthma therapy was presented at a late-breaking session at ATS 2022.