The HCPLive conference coverage page features articles, videos, and expert-led live coverage from major medical meetings throughout the year.
John Botson, MD: Pegloticase Plus Methotrexate For Gout
A clinical rheumatologist breaks down how the combination therapy can be used to treat uncontrolled gout.
Filgotinib Effective for Patients With Rheumatoid Arthritis
The drug is well-tolerated in methotrexate inadequate response patients with rheumatoid arthritis.
Tocilizumab Shows Similar Efficacy to Other Targeted Immune Modulators
Patients who cannot tolerate cDMARDs may experience additional value from tocilizumab compared to adalimumab.
Philip Mease, MD: Taking Conferences Virtual in the Age of COVID-19
Dr. Philip Mease explains the next steps for testing the efficacy and safety of upadacitinib for patients with psoriatic arthritis.
Dennis McGonagle, PhD: The Future of Guselkumab for Psoriatic Arthritis
Dr. Dennis McGonagle said guslekumab is also being tested in patients with inflammatory bowel disease.
Philip Mease, MD: The Relationship Between Psoriatic Arthritis and IBD
Dr. Philip Mease discusses some of the treatments currently being tested for effectiveness against COVID-19.
Tofacitinib Reduces Psychiatric Disorder Rates in Rheumatoid Arthritis Patients
Rheumatoid arthritis patients with probably major depressive disorder or generalized anxiety disorder were more likely to suffer from worse fatigue and pain.
Philip Mease, MD: Upadacitinib Showing Promise Treating Psoriatic Arthritis
Dr. Philip Mease explains the relationship between rheumatoid arthritis and psoriatic arthritis.
Methotrexate and Pegloticase Treatment Improves Uncontrolled Gout
More patients maintain therapeutic response when treated concomitantly with methotrexate and pegloticase when compared to those who use pegloticase alone.
Serious Infection More Likely in Older Rheumatoid Arthritis Patients
A team investigated data from trials of tofacitinib, adalimumab, and placebo.
Secukinumab Reduces Spinal Pain for Axial Spondyloarthritis
Study drug also recently showed promise in treating psoriatic arthritis.
Ixekizumab Improves Signs and Symptoms of Psoriatic Arthritis
The safety profile is consistent with previous studies of the ixekizumab.
Upadacitinib Improves Rheumatoid Arthritis Symptoms Over Abatacept
The safety profile of upadacitinib is consistent with phase 3 rheumatoid arthritis studies.
Tofacitinib Bests Placebo in Psoriatic Arthritis Trial
Remission and LDA rates generally increased over time in patients with psoriatic arthritis receiving tofacitinib.
Upadacitinib Outperforms Placebo, Adalimumab for Psoriatic Arthritis
The late-breaking data reveal the safety and efficacy of upadacitinib versus placebo and adalimumab.
Belimumab Safe and Effective Treating Systemic Lupus Erythematosus
Asian countries regularly see higher rates of SLE prevalence globally.
Higher Doses of Upadacitinib Increase Rate of Serious Infections
The incidence rate of serious infection events and opportunistic infections was higher among the upadacitinib 30 mg group than the 15 mg group.
Netakimab Rapidly Improves Axial Disease
The findings are based on data from a 24-week observation from an ongoing phase 3 PATERA study.
Nanoparticle Treatment Showing Promise Against Rheumatoid Arthritis
In a late-breaking abstract, investigators test nanoparticle treatment using in vivo models.
Positive Results Treating Active Psoriatic Arthritis with Upadacitinib
In an abstract presented at EULAR 2020, investigators find more serious adverse events in the upadacitinib treatment arms compared to placebo.
Ixekizumab Improves Psoriatic Arthritis Pain, Fatigue
Patients report sustained improvements in pain and fatigue from taking ixekizumab every 2 or 4 weeks over 3 years.
RA Patients With ACPA or RF Positivity Less Likely to Discontinue Abatacept
The findings are important to understand treatment persistence and switch patterns in rheumatoid arthritis patients with poor prognostic factors in a real-world setting.
Gut Microbiome Hints at Lupus Nephritis Disease Activity
Dr. Gregg Silverman said identification of Ruminococcus gnavus could allow earlier diagnosis of lupus nephritis.
Tanezumab Outperforms Placebo, Tramadol in Improving Chronic Back Pain
Findings suggest 5-10 mg of tanezumab significantly improve pain versus placebo in patients with chronic low back pain.
Upadacitinib Improves Rheumatoid Arthritis Pain, Function Over Adalimumab
The results highlight a significant improvement in rheumatoid arthritis signs and symptoms for those who used upadacitinib over placebo and adalimumab.
Upadacitinib Reduces Key Biomarker for Rheumatoid Arthritis
In a study presented at EULAR, investigators find 14-3-3η baseline levels did not correlate with baseline mTSS.
Guselkumab Effective Treating Dactylitis and Enthesitis
In both DISCOVER trials, investigators find guselkumab effective against active psoriatic arthritis domains.
Apremilast Effective Treating Genital Ulcers Linked to Active Behcet's Syndrome
The treatment has already proven to reduce oral ulcers associated with Behcet’s syndrome.
Different Forms of Adalimumab Safe, Effective in RA Patients
Patients are unaffected by the switch from ADL-EU to ADL-PF.
Advancing Biologic Research in Asthma
How clinical data for the interleukin-targeting class will begin to dictate more treatement decisions and research progression.