On the HCPLive news page, resources on the topics of disease- and specialty-specific medical news and expert insight can be found. Content includes articles, interviews, videos, podcasts, and breaking news on health care research, treatment, and drug development.
FDA Approves High-Concentration Formulation Biosimilar Adalimumab-Adaz
The approval was based on positive results from the phase I pharmacokinetics bridging study, which showed comparable PK and similar safety and immunogenicity of adalimumab 50 mg/mL and adalimumab high-concentration formulation.
Phase 3 DISSOLVE Trials Prove SEL-212's Urate-Lowering Ability in Chronic Gout
March 21st 2023An announcement from Selecta Biosciences and Sobi provide the latest update on DISSOLVE clinical program, with new data indicating SEL-212 met the primary endpoint of achieving serum urate control during month 6.
Bruce Feinberg, DO: Common Hesitancies Observed Among Providers Switching to Biosimilars
Bruce Feinberg, DO, noted that although patients and providers ultimately understand that a biosimilar should theoretically be just as effective as a biologic, prescribers may still be wary of switching patients to a different product when they have historically experienced an excellent response to the original treatment.
Bruce Feinberg, DO: Differences Among Specialties in Biosimilar Uptake
Bruce Feinberg, DO, explained how Cardinal Health used its 2023 Biosimilars Report to better understand the provider's insight on industry changes that are occurring due to the expansion of biosimilars.
Abatacept Misses Mark for Preventing Type 1 Diabetes in Phase 2 Trial
March 20th 2023In a recent phase 2 trial, abatacept failed to significantly reduce progression to diabetes or abnormal glucose tolerance among a cohort of stage 1 relatives of people with type 1 diabetes considered to be at risk of progression.
Nexvax2 Does not Result in Gluten-Induced Symptom Reduction for Celiac Patients
The mean change from baseline to the day of the first masked gluten challenge in total gastrointestinal scores for the non-homozygous Nexvax2 group was 2.86 compared to 2.63 for the non-homozygous placebo group.
Rising Gestational Diabetes Rates Could Be Result of Changes in Screening Practices
March 20th 2023An analysis of more than 500,000 pregnancies over a 15-year period suggests much of the increase in gestational diabetes rates observed during the study period can be attributed to changes in screening practices.