News

The phase 3 DISCOVER-1 and DISCOVER-2 studies were used to evaluate dactylitis resolution in guselkumab-treated patients with psoriatic arthritis through 1 year.

A remote hypertension management program at Mass General Brigham was associated with significant improvements in blood pressure control despite systemic disruptions in care due to the COVID‐19 pandemic.

While this population was previously thought to be unaffected, studies within the last few years have shown that women with hemophilia experience joint and bleeding problems.

Polypharmacy, defined as ≥5 concomitant drugs, was significantly higher in patients with psoriatic arthritis when compared with controls (49% vs 17%, respectively).

A multinational study provides new insight into the impact of suboptimal sleep duration on risk of incident peripheral artery disease.

There was a lower probability of initiating psycholeptics and having postpartum psychiatric emergencies in the early discontinuer and late discontinuer groups compared to the continuers.

A 13-week trial examining use of the Control-IQ closed-loop insulin delivery system in children aged 2-6 years, results of PEDAP indicate use of the closed-loop system was associated with a 3 hour per day increase in time in range relative to standard care.

A recent study indicated that lebrikizumab treatment for 16 weeks was effective for adolescents and adults with moderate-to-severe atopic dermatitis.

Practicing oral hygiene improves health issues from gum disease to cardiac disease, and Lebovic believes nasal hygiene can have that impact as well.

Adult patients with traumatic brain injury-induced fibromyalgia were randomized 1:1 to receive hyperbaric oxygen therapy or pharmacological intervention.

Children living in areas with greater neighborhood deprivation in the US have a higher likelihood of being diagnosed with primary hypertension, according to an analysis of more than 65,000 children.

After a year of treatment with once-weekly antihemophilic factor (recombinant), Fc-VWF-XTEN Fusion Protein-ehtl, results show patient pain was significantly reduced and quality of life significantly increased.

"The anticipation would be–wash your hands, brush your teeth, clean your nose–and allow that process to help the patients who suffer from allergy symptoms," lead investigator Dr. Arman Kalmakarian says.

New phase 3 trial data was announced by Dermavant Sciences indicating strong results for both efficacy and safety of tapinarof treatment for atopic dermatitis.

Combination therapy of brolucizumab and monthly aflibercept monthly appeared well-tolerated and may be considered for eyes with macular fluid on every-8-week brolucizumab.

The overall survival after adjusting for tumor stage showed tumor adipose feature was independently prognostic as both a binary feature and as a semiquantitative categorical feature.

No sign of harmful impacts related to the mandatory biosimilar switching policy for patients with inflammatory bowel diseases treated with infliximab was observed in the cohort study.

An analysis of data from a 50-year prospective study provides insight into the effects of different pregnancy complications on all-cause mortality later in life.

New research was conducted into treating Stevens-Johnson syndrome/toxic epidermal necrolysis patients with plasmapheresis before intravenous immunoglobulin therapy.

The prevalence of CDI in southern China was 11.0% and 13.6% in northern China.

New research indicates cooccurring edentulism and diabetes mellitus were linked to accelerated cognitive decline among participants in a nationally representative sample of older adults.

Results shows female adolescents are more likely to transition into and out of insulin resistance, whereas adolescent males are more consistently normal.

A recent study found no association between exposure to rituximab biosimilars and hospitalization for hypersensitivity reactions compared to the biologic at initiation, at switch, or over time.

Higher serum 25(OH)D level was related to an increased risk of early AMD in those aged 60 years or younger, and decreased risk of late AMD in individuals older than 60 years.

In addition to sharing how a novel machine learning method may one day soon predict lung disease susceptibility, Kalhan describes the science behind the ALA Lung Health Cohort Research Study.

A significant decrease in indirect costs was observed in patients switching from intravenous to subcutaneous CT-P13, which was attributed to lower total costs overall.

The analysis of AMD progression found significant associations between worse initial visual acuity, the presence of wet AMD subtype in fellow eyes, and thyroxine treatment with disease development.

An analysis of more than 800,000 children with more than 3.5 million person-years of follow-up indicate those in the upper range of average BMI had a 26% greater risk of developing hypertension, with each per unit increase in BMI associated with a 4% increase in risk of hypertension.

Clostridium difficile and Clostridium perfringens were found in 83% of newborns nursed by formula milk in the second week of life, but all infants by the end of the third week of life.

A new study indicated that body surface area predicted erythema-type chronic graft-vs-host disease survival more accurately than NIH Skin Scores.