News

A systematic review and meta-analysis of data from more than a dozen RCTs provide a comprehensive overview of the effects of metformin plus oral contraceptives compared to oral contraceptives alone in women with polycystic ovary syndrome without obesity.

The NDA has been granted Priority Review with a PDUFA goal date of August 19, 2023. The FDA is not currently planning to hold an Advisory Committee meeting.

In an interview with Maria Teresa García-Romero, MD, MPH, a discussion was held regarding the need for a morphea severity tool for pediatric patients.

A research letter addresses the challenges of accurately diagnosing asthma, atopic eczema, and allergic rhinitis in children under 5 years old and the use of Read codes and prescription data as diagnostic criteria.

Age less than 3 months at surgery was associated with an elevated risk of glaucoma-related adverse events in aphakic eyes, but children with pseudophakia were less likely to develop a glaucoma-related adverse event.

Many conditions have a genetic element, meaning that relatives have a heightened risk. How much do you know about the hereditary nature of rheumatoid arthritis and what that means for first-degree relatives? Test your knowledge with this quiz.

According to the data, sleep quality, fatigue, and social well-being contribute to depression among young adults with autism, with social well-being being a significant predictor of depression over a 2-year period.

A new analysis cautions against the use of the Amsler grid test, suggesting its performance is not at a level recommended for monitoring in a patient population with an a priori risk of nAMD.

Anisha Dua, MD, MPH, emphasized the looming workforce shortage, the challenges of attracting medical students to this field, and how practices changed during the COVID-19 pandemic.

Data from the phase 2 CLUE trial provide insight into the safety and efficacy of tigulixostat as a serum urate-lowering therapy in patients with gout with hyperuricemia.

New research into global trends in atopic dermatitis over 3 decades assessed regional and income differences in adolescent eczema patients.

Using data from a pair of major studies, investigators from the Harvard T.H. Chan School of Public Health shed new light on the impact of low-carbohydrate diet scores in people with type 2 diabetes.

Mental health outcomes for those with hidradenitis suppurativa who have had a previous surgery were explored in recent research.

Acceptability of the vaccine was high among the completers and some non-completers that felt it was safe and offered them protection.

Anisha Dua, MD, MPH, defines IgG4 and explains why IgG4-related disease is often difficult to diagnose, in part because it regularly affects a variety of organ systems.

The new analysis on the screening tool in primary care patients with COPD highlights the need for further research to optimize CAPTURE's performance and impact on clinical outcomes.

An analysis of the China Stroke Primary Prevention Trial revealed the correlation was more notable when stratified by triglycerides levels and smoking status.

In this Q&A, Rubén Queiro, MD, PhD, discussed the findings of a study that evaluated the retention rate and safety of ixekizumab in patients with psoriatic arthritis in real clinical practice conditions.

Once-weekly efanesoctocog alfa is a safe and effective treatment for patients with severe hemophilia A, providing better outcomes than current treatment options by significantly reducing bleeding rates and improving physical health, pain, and joint health.

A nationwide study from the United Kingdom identified a low overall prevalence of stress-induced burnout by cataract surgery but reported a reduction in the feelings of personal achievement and a significant proportion willing to give up surgical responsibilities.

From new ACG GERD guidelines to the efficacy of colonoscopies, our latest issue addresses topics changing practice and stirring conversation.

A review of changes to clinical, dietary and screening strategies for patients with GERD.

A northern Europe-based trial highlights the potential impact of streamlined and community-supported colonoscopy screening for cancer.

A recent randomized controlled trial showed the limitations of either option, despite being a cornerstone of care.

Analysis from a multicenter, randomized, double-blind, parallel group study comparing the drugs as induction and maintenance therapies in biologic-naïve patients.

An analysis of data from more than 20,000 adults with a documented COVID-19 infection from Los Angeles, CA has brought forth results the investigators suggest prove the association between COVID-19 infection and increased risk of type 2 diabetes, regardless of vaccination status.

New data show the FDA's rationale for approving drugs with unmet efficacy end points in pivotal trials has been inconsistent since at least 2018.

There have been only 12 unique studies evaluating this treatment for the primary and secondary prevention of CDI, with only 1 conducted prospectively.

An analysis of actigraphy data obtained from the MESA Sleep Ancillary Study indicates irregularities in sleep patterns, particularly in duration and timing of sleep, were linked to increased markers of subclinical atherosclerosis, including increased coronary artery calcium burden.