Considerations Regarding Patient Selection for JAK Inhibitors

Key Takeaways

• JAK inhibitors are effective for moderate to severe alopecia, especially in patients unresponsive to conventional therapies.
• Ideal candidates are those with significant hair loss affecting quality of life.
• Caution is necessary for patients with malignancies, active infections, or immunocompromised status due to immune modulation.
• Patients with thromboembolic history or cardiovascular risks need thorough evaluation before treatment initiation.