Cardiology

However, researchers at IDWeek 2012 said that although the drug showed a biological and a clinical effect during a phase III study, it did not meet the primary efficacy outcome.

Researchers at IDWeek 2012 presented new information and guidance on the diagnosis and management of three of the most deadly infectious diseases: pneumonia, meningitis, and endocarditis.

Investigators at more than one dozen sites will enroll hundreds of neurologically injured patients to study the effects of low serum sodium concentrations prior to therapy.

Hyponatremia is frequently seen in patients with hepatic impairment and portal hypertension, and is associated with wide range of severe complications and comorbidities. Pharmacologic treatment with vasopressin receptor antagonists offer management options beyond standard therapy.

In the first long-term active-comparator trial of efficacy and augmentation in restless leg syndrome (RLS), outcomes with pregabalin were better than those observed with pramipexole.

Although the intra-cerebral hemorrhage (ICH) score at hospital admission is typically used to estimate the potential prognosis in stroke patients, a new study suggests that the 24-hour ICH score is a more accurate assessment.

According to a randomized, controlled clinical trial reported at the Emerging Science session, pregabalin was found effective in relieving chronic neuropathic pain and pain-related sleep disturbances associated with spinal cord injury.

Results from the FREEDOMS II trial found oral fingolimod administered at a daily dose of 0.5 mg to reduce relapse rates by almost 50% in patients with relapsing-remitting multiple sclerosis (RRMS).

Mark F. Mehler, MD, discussed how brain and behavior are becoming better understood through the emerging discipline of epigenetics.

The 2012 Annual Meeting of the American Academy of Neurology presented a phase 3 randomized, double-blind clinical trial which found that levodopa-carbidopa intestinal gel was more effective than standard oral levodopa-carbidopa.

In this video about hyponatremia, Dr. Paul Kattupalli reviews some of the important things healthcare professionals need to remember when treating patients with hyponatremia.

An investigational oral drug for multiple sclerosis (MS), called ONO-4641, reduced the number of lesions detected on magnetic resonance imaging (MRI) scans

Updated guidelines for prevention of chronic migraine headache were unveiled during the 2012 Annual Meeting of the American Academy of Neurology.

A new study presented at the 2012 Annual Meeting of the American Academy of Neurology suggests that the drug florbetaben can be used as a biomarker with positron emission tomography (PET) imaging to diagnose AD by detecting amyloid plaques in the brains of living people suspected of having AD.

Dr. Sacco highlights some of the key takeaway points that he will speaking about during the Robert Wartenberg Lecture at this year's AAN Annual Meeting. He also discusses his involvement in the Northern Manhattan Study, which evaluates stroke in African and Hispanic Americans.

Tolvaptan, a vasopression V2 receptor antagonist used to increase low levels of sodium in the blood, could be a cost effective way of managing patients who have hyponatremia.

The Million Hearts program, which led to February being named American Heart Month, and Wear Red Day, established by the American Heart Association to focus attention on women's heart issues, are both intended to reduce the toll of cardiovascular disease.

Research on people recruited randomly from the community suggests that, after adjusting for various demographic, behavioral, and physical characteristics, there is no association between sleep apnea and hypertension.

Poor sleep is connected to a significantly increased risk for major cardiovascular and metabolic disorders, such as obesity, diabetes, and coronary artery disease, researchers at the University of Pennsylvania's Perelman School of Medicine have found.

People with one or more risk factors for cardiovascular disease in middle age are significantly more likely to suffer a major cardiovascular event, such as heart attack or stroke, for decades afterwards, a large-scale analysis of previous studies indicates.

Participants in the London marathon have a spotty understanding of the causes and potential dangers of exercise-associated hyponatremia, researchers at the Centre for Sports and Exercise Medicine at the University of London have found.

Regular monthly contact with a nurse increases the quality of life for patients with diabetes or hypertension, a recent study has found.

A study of over 10 million runners of marathons and half-marathons has found that participating in these events is associated with a low risk of cardiac arrest compared with other athletic activities.

The likelihood of having a heart attack increases dramatically in the first 24 hours after the death of a loved one and remains elevated for days and weeks afterward, researchers have found.

Hyponatremia is independently associated with a long-term increase in mortality and rehospitalization for chronic heart failure patients, researchers at the Duke Clinical Research Institute have found.

The anticoagulant dabigatran has been linked to a heightened risk of myocardial infarction in a wide range of patients when compared to other medications.