Endocrinology

Using nutritional supplement mixtures consisting of arginine, glutamine, and beta-hydroxy-beta-methylbutyrate (HMB) may speed up wound healing in diabetic foot ulcers.

Though many patients indicate side effects as the reason they stop taking their prescribed statins, clinical trials have not documented high discontinuation rates due to adverse drug reactions.

A group of researchers have determined that thyroid cancer is an over-diagnosed disease.

Researchers have published their findings from the NIH-sponsored Look AHEAD clinical trial in three areas relevant to type 2 diabetes management.

Patients who are unaware that they have diabetes may have less contact with healthcare professionals, receive less aggressive treatment, or have a poorer understanding of the disease and the actions required to treat it - all of which may be responsible for their increased risk of morbidity and mortality.

In clinical testing, the MD-Logic Artificial Pancreas system significantly improved overnight glucose control and decreased the duration of hypoglycemia in type 1 diabetes patients.

Research findings from a group of Midwest-based investigators suggest bipolar disorder (BD) is linked to different illness burdens in binge eaters compared to obese patients who do not experience compulsive episodes of uncontrollable overeating.

HIV-infected patients face increased risk of myocardial infarction, as well as higher risk for ART-associated dyslipidemia and insulin resistance.

The US Food and Drug Administration (FDA) has approved Noven Pharmaceuticals Inc.'s once-daily Brisdelle (paroxetine) capsules to reduce moderate to severe hot flashes and night sweats that can last up to five years in menopausal women.

Recognizing that melatonin secretion from the gastrointestinal (GI) tract improves abdominal pain in irritable bowel syndrome (IBS) but decreases with age, Polish researchers from the Medical University of Lodz aimed to define the effect of administering melatonin in postmenopausal women with different predominating IBS symptoms.

By adopting a comprehensive set of case management policies for the care of diabetic and hyperglycemic patients, Johns Hopkins Hospital improved in-hospital mortality rate, reduced length of stay, and reduced hyperglycemia.

Exposure to insulin glargine and metformin did not cause increased risk of cancer or worse cancer outcomes.

Results of a three-year trial of the experimental GLP-1 receptor agonist albiglutide showed that it had a better effect on HbA1c, fasting blood glucose, and body weight than two comparator drugs.

Prescription-strength doses of vitamin D improve highly prevalent comorbidities among diabetic women, such as depression and pain, and also improve risk factors such as excess weight and high blood pressure.

While the current ADA guidelines recommend targeting HbA1c levels to below 8% for high-risk patients with diabetes, reducing the level to 5.7% dose not raise CVD or overall mortality risk, according to a recent study.

A novel algorithm for patient self-adjustment of prandial insulin dose could make it easier for patients who are poorly-controlled on basal insulin to add meal-time insulin.

In patients with type 2 diabetes currently taking metformin, treatment with combination exenatide plus insulin glargine decreased fasting glucose and resulted in greater weight loss compared to treatment with insulin lispro plus insulin glargine.

Study shows dulaglutide improved glycemic control in patients at 52 weeks compared to sitagliptin, but with a higher rate of adverse events.

Study shows a combination of liraglutide and the genetically modified insulin analog degludec was safe and improved HbA1c levels, weight loss, and hypoglycemia outcomes in patients with type 2 diabetes.

The Diabetes Resource Guide highlights 20 websites that feature articles on topics such as ways to address and improve lifestyle factors (such as diet), how to live day to day with diabetes, information about diabetes medications, online forums, and more.

Hypertriglyceridemia combined with insulin resistance may lead to increased platelet activation in women with polycystic ovary syndrome (PCOS).

Insulin sensitivity improved after three nights of adequate sleep in nondiabetic men after days of inadequate sleep.

Study results suggest that tight glycemic control is associated with decreased length of stay and improved mortality.

Results of a recent meta-analysis suggest lower rates of hypoglycemia with insulin degludec in obese patients when compared with insulin glargine.

Study shows that 12 weeks of vitamin D supplementation in obese adolescents does not affect cardiometabolic risk factors.

At ENDO 2013, an expert panel discussed the consensus statement on the evaluation and treatment of hypertriglyceridemia and the evidence supporting the recommendations.

Study results show improvements in body composition, intrahepatic lipids, and cardiovascular risk markers in obese men treated with growth hormone for six months compared with placebo.

In cell culture and mice studies, bazedoxifene inhibited estrogen-induced gene expression and cell proliferation in cancer cells, including those that were tamoxifen-resistant.

Initial data show similar efficacy but different costs among injectable insulin treatments for patients who fail oral antidiabetic drugs.

A recent study suggests that skipping breakfast in overweight women may lead to insulin resistance.