Hormonal Disorders

The latest endocrine case report from Brady Pregerson, MD, features a woman in her mid-30s presenting with swollen glands lasting for the past 3 days and an associated sore throat. Can you determine the correct diagnosis?

An analysis of nearly 400 patients suggests undergoing thyroid radiofrequency ablation in ambulatory settings was associated with increased risk of intraoperative, postoperative, and perioperative side effects than those performed in operating room settings.

An analysis of more than 650 thyroid eye disease patients is providing clinicians with insight into the most common comorbidities and risk factors associated with increased disease severity in patients with TED.

An analysis of data from OPTIC and OPTIC-X provide insight into the effects of teprotumumab in longer duration thyroid eye disease and among patients who were nonresponders in the original trial.

Results of a bioavailability, crossover study suggest use of proton pump inhibitors did not interfere with the absorption of levothyroxine sodium oral solution.

Analysis of claims data from the Symphony database offers clinicians greater insight into the impact of diabetes, both type 1 and type 2, on thyroid eye disease in US patients.

A systematic review and meta-analysis presented at AACE 2021 details the risk of cardiovascular disease in patients with thyroid cancer who have undergone thyroidectomy.

Data from a phase 1 trial comparing dosing 15 and 30 minutes prior to breakfast suggests the wait time between intake of the novel liquid formulation of levothyroxine, Tirosint-SOL, and breakfast could be shortened to 15 minutes.

Data from LINC3 and LINC4 provide insight into the impact of dosing titration schedules on risk of hypocortisolism-related adverse events associated with osilodrostat use in patients with Cushing's disease.

A study from ENDO 2021 indicates moderate-to-severe COVID-19 infections are associated with atypical thyroid inflammation.

A randomized, 3-arm study is giving further insight into the effects of levothyroxine monotherapy compared against a thyroid combination therapy and desiccated thyroid extract for management of hypothyroidism, particularly in patients with Thr92AlaD2 polymorphism.

An analysis of more than half a million thyroid hormone users indicates more than 30% were also concurrently receiving a medication known to interfere with thyroid function tests.

An analysis of data from the TRUST trial supports guideline recommendations against levothyroxine for reducing depressive symptoms in older adults with subclinical hypothyroidism.

Check out this Emergency Department Minute Quiz from Brady Pregerson, MD. Can you determine the correct diagnosis?

How good are your diagnostic skills? Test them with this month's Visual Dx quiz!

Study suggests generic levothyroxine achieved similar rates of patients with thyrotropin levels in the ideal range as brand name levothyroxine.

Results of the study offer clinicians greater insight and could improve decision-making in regards to treatment choices for hypothyroidism.

A study from e-ECE 2020 suggests thyroid inflammation could put patients at greater risk for developing an anxiety disorder.

A survey of more than 600 physicians found many endorsed the use of thyroid ultrasonography for clinically unsupported reasons.

New research is comparing the long-term risk of death from solid cancers in patients treated with radioactive iodine, antithyroid drugs, or surgery for hyperthyroidism.

New data disputes the findings of previous observational studies examining the effects of levothyroxine on cardiac function.

New research is defining how primary care providers view their role in long-term survivorship care of patients with thyroid cancer.

A new case study published in The Journal of Clinical Endocrinology & Metabolism, reports on an 18-year-old patient with COVID-19 infection and subacute thyroiditis.

The common synthetic thyroid medication L-thyroxine has been shown to be ineffective in reducing symptoms in patients with subclinical hypothyroidism (SCH), according to a study published in the Annals of Internal Medicine.

New research shows teprotumumab can be a beneficial treatment for patients suffering from thyroid eye disease (TED), even across age, gender and risk factor-based subgroups. In an interview with HCPLive®, Raymond Douglas, MD, PhD, director of the Orbital and Thyroid Eye Disease Center at the Cedars-Sinai Medical Center, explained the importance of the teprotumumab in treating this patient group and how the coronavirus disease 2019 (COVID-19) might impact thyroid eye disease patients.

The FDA announced yesterday that it has approved the first treatment for thyroid eye disease:  teprotumumab-trbw (Tepezza, Horizon Therapeutics).

Restoring normal thyroid function may reverse cold-induced thermogenesis, say researchers writing in the journal Thyroid.

Adults with subclinical hypothyroidism do not need thyroid hormone therapy in most cases, states a BMJ Rapid Recommendation issued this month.

Thyroid hormones have a wide range of effects of the cardiovascular system. Too much or too little thyroiid hormones can induce or exacerbate existing cardiovascular disorders. In this article, we highlight the treatment recommendations for thyroid-related CVD events.

Study of levoketoconazole for Cushing’s syndrome shows significant improvements in acne, hirsutism in women, and peripheral edema.