Type 2 Diabetes

Cardiology Review editor-in-chief Debabrata Mukherjee, MD, reviews the contents of this month's issue.

Women with a history of depression could be more likely to develop gestational diabetes according to the results of a recent study.

This short slide show summarizes results of 8 phase III clinical trials, revealing favorable class efficacy and also differences that should be considered before treatment selection.

Studies have identified lower-than-normal BMIs to be associated with higher mortality in comparison with normal body weight and overweight individuals in patients with coronary artery disease. This has given rise to the term "obesity paradox" in which being overweight/obese confers a survival advantage in individuals that have been diagnosed with a medical condition. Against this backdrop, this study attempted to evaluate whether there is an association between BMI and death risk among patients with type 2 diabetes mellitus.

It's probably too early to pass judgment but data from clinical trials point to decreased bone mineral density and increased treatment-emergent fractures in patients taking the new antidiabetes drugs.

SGLT2 inhibitors have been studied in combination therapy with a range of antihyperglycemic agents. Check your math, here, with our 6 "add-on" questions.

Recent studies have shown strong links between patients who are obese and also have issues with sleep as part of their diabetes diagnosis.

Making full use of its "breakthrough therapy" accelerated review protocol the US Food and Drug Administration in 2014 approved 51 new therapies, the most in 18 years.

Doctors around the world face their own individual challenges depending on where they are working with patients. In Africa those challenges include not only difficulty affording medication, but in some cases having proper ways to properly store them.

A Danish study found reduced endogenous levels of glucagon-like peptide-1 in persons with prediabetes. Perhaps the incretin system defect comes first.

There are 10 FDA-approved DPP-4 inhibitors--single agents and combination products. Do you speak their language? Find out with these 5 questions.

The FDA approved a second drug to treat diabetic retinopathy in patients with diabetic macular edema.

Approximately 14% of patients infected with human immunodeficiency virus (HIV) also have type 2 diabetes mellitus. That number is expected to rise as the population of HIV-infected patients ages and develop associated chronic comorbidities.

Superficial fat necrosis is a rare complication of insulin injections that can manifest with severe, persistent, and well-localized pain.

Spot check your memory for these disease details.

Trade names often mask the essential nature of a medication, but some of the new agents that treat type 2 diabetes take it to a new level. Here, 5 chances to see what you know.

A new post-hoc analysis suggests that what’s good for hyperglycemia may also be good for hyperuricemia.

At 52 weeks, dulaglutide resulted in significantly greater reductions in HbA1c, FPG, and weight compared with the DPP-4 inhibitor sitagliptin.

In obese patients with type 2 diabetes uncontrolled by lifestyle and two oral agents, albiglutide significantly lowered A1c as part of 3-drug therapy.

Conditions associated with long-term diabetes affect myriad organs and systems. Which one of these comorbidities is not associated with the disease?

A prototype model of a temporary tattoo like device is able to accurately monitor glucose levels, according to research published in Analytical Chemistry.

A recent Centers for Disease Control and Prevention (CDC) study revealed 86 million Americans suffer from prediabetes, a modifiable risk factor for cardiovascular disease (CVD), and nearly half of prediabetic patients were reported to develop frank diabetes.

Jamal Rana, MD, Oakland, CA, presented research results on metabolic dyslipidemia and the risk of coronary heart disease (CHD) in adults with diabetes and low LDL-cholesterol.

Chronic illness treatment typically involves some level of long-term use of pharmacotherapy. While these medications may prove efficacious in contesting the disease, their full benefits often go unmet, because nearly 50% of patients do not to take the medications as prescribed.

What are some of the esophageal complications seen in patients with long-standing hyperglycemia?

With the number of patients diagnosed with diabetes continuously rising efforts are being made to find new ways to treat the condition beyond insulin and other traditional medications.

Like most medical fields endocrinology has seen changes in doctor recruitment, patient relationships, and overall care. The future of the field is discussed by the president of the Endocrine Society

Medical research is learning new ways to use the gut microbiota every day. From gastroenterology to oncology there are constantly new ideas on how it can help improve a patient's health.

Does bariatric surgery prolong life? Past research has shown that this surgery initiates sustainable weight loss, sends type 2 diabetes into remission, and reduces cardiovascular disease.

Researchers from Joslin Diabetes Center at Harvard Medical School may have uncovered an explanation for why patients with diabetes are more likely to develop anxiety and depression than patients with other chronic conditions requiring similar levels of management.